Abutilon indicum (Môv) : medicinal properties in alcoholic extraction

Venkateswarlu K et al, Evaluation of Antiulcer Activity of Hydro Alcoholic Extracts of Abutilon indicum, Helianthus annuus & Combination of Both against Ethanol & Pyloric Ligation Induced Gastric Ulcer in Albino Wistar Rats, British Jl of Pharmaceut Res, 5(1): 42-51, 2015.-Abstract: Abutilon indicum & Helianthus annuus consists of various compounds which have different therapeutic activities. Objective: The main aim of the present study was to compare the antiulcer activity of hydroalcoholic extracts of A. indicum H. annuus & combination of both against Ethanol induced gastric ulcer & pylor…

Shanmugapriya S et al, Formulation & evaluation of Abutilon indicum & Boerhaavia diffusa for the determination of nephroprotective activities, Sci Transactions in Env. & Technovation, 2015-Abstract: In vivo anti nephrotoxic activities of the whole plants of Abutilon indicum & Boerhaavia diffusa, their formulation & individual extracts were determined in in-vivo models against nephrotoxicity in rats, induced with Gentamicin. A control group (water, group I, n = 6) was compared with rats administrated 40 mg/kg Gentamicin, once daily for 21 days (Groups II, III, IV, V & VI). The effect of etha…

Subramani R., Pharmacognostical phytochemical including GC-MS investigation of ethanolic leaf extracts of Abutilon indicum (Linn). Asian Jl. Pharm.Ana; (4): 88-92.2011-Abstract: Abutilon indicum (Linn) family (Malvaceae) popularly known as Atibala is used as one of the most important drugs in Traditional System of Medicine to treat various ailments. The plant is used due to its various properties as; demulcent, diuretics, anti-diabetic, anthelmintics, astringent, laxative, expectorant, antibacterial & antifungal activities. The Present research describes the simplest method of identificatio…

Krisanapun C et al, Aqueous extract of Abutilon indicum Sweet inhibits glucose absorption & stimulates insulin secretion in rodents, Nutr Res, 29(8) :579-87,

Khanduri CN, Fertility Control of Female Rat Through Abutilon Indicum Seeds, INT Jl OF TECHNOL ENHANCEMENTS & EMERGING ENGINE RES, 2, :3 89 ISSN 2347-4289,

KRISANAPUN C, Thesis: HYPOGLYCEMIC EFFECT & MECHANISMS OF ACTION OF EXTRACT FROM ABUTILON INDICUM SWEET,

Krisanapun C et al, Antidiabetic Activities of Abutilon indicum (L.) Sweet are Mediated by Enhancement of Adipocyte Differentiation & Activation of the GLUT1 Promoter, eCAM, doi:10.1093/eCAM/neq004,

Stefek M, Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract. Interdiscip.Toxicol, (2): 69-77. 2011,

PORCHEZHIAN E, Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats, Phytomed, 12(1):62-64-Abstract: The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- & paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- & paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination. The plant extract may interfere with free-radical formation, which may conclude in hepatoprotective action. Acute t…

Pingale SS et al, Evaluation of acute toxicity for Abutilon indicum, Der Pharmacia Lettre, 3(3):37-42, 2011, -Abstract: The present study investigated the acute toxicity of Abutilon indicum plant material in Swiss mice. The plant material was administered orally at dose ranging from 2gm to 10gm/Kg body weight as well as 10g/Kg body weight plant material as well as 10ml/Kg juice of fresh leaves & the animals were observed continuously for the first 4 hours for any behavior changes and they were then kept under observation up to 14 days after drug administration to find out the mortality. Fro…

Kaushik P et al, Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin-Induced Experimental Diabetes in Rats, Inter J of Pharmacogn & Phytochem Res, 2010; 2(2); 45-9,

Sharma A et al, Phytochemical & Pharmacological Profile of Abutilon Indicum L. Sweet: A Review, Int Jl. Pharm. Sci. Rev. Res., 20(1), 2013; 120-7,

Shrikanth VM et al, In-vitro anti snake venom potential of Abutilon indicum Linn leaf extracts against Echis carinatus (Indian saw scaled viper), Jl of Pharmacogn & Phytochem, 2014; 3 (1): 111-7-Abstract:  The present study evaluates the in vitro anti venom potential of Abutilon indicum leaves extract against Echis carinatus (Saw Scaled Viper) venom. The leaf extracts of A. indicum were used to evaluate the enzyme inhibiting activity of protease, phosphomonoesterase, phosphodiesterase, acetylcholinesterase, phospholipase A2, hyaluronidase & L-amino acid oxidase toxic enzymes present in snak…

Kaka Saheb J et al, Effect of Abutilon indicum Extract in Gentamicin Induced Nephrotoxicity. Inter Jl of Pharmaceut Res & Devt 2011; 3(7): 73-9.

Jacob Jesurun RS et al, Nephroprotective effect of ethanolic extract of abutilon indicum root in gentamicin induced acute renal failure, Inter Jl of Basic & Clin Pharmacol, 5 :3 2016-Abstract: The present study was to evaluate the nephron protective effect of abutilon indicum root in gentamicin induced acute renal failure in Wistar albino rats. Methods: Experimental evaluation was done in gentamicin induced acute renal failure. 24 rats were divided into 6 in each group. Group 1 was given normal saline (10 ml/kg) per oral, group 2 with gentamicin (100 mg/kg, ip for 5 days), group 3 with gen…

Chakraborty AK et al, Phytochemical Screening & in vivo Fertility Enhancing Activity (Aphrodisiac) of Abutilon indicum Roots on Male Wistar Rats, Asian Jl of Chem Sci, 2456-7795, 2 ;2-Abstract: The plant Abutilon indicum (Linn) is an important medicinal plant used in our Traditional System of Medicine to treat various health aliments. The plant has been traditionally used for used as demulcent, aphrodisiac, laxative, diuretic, pulmonary & sedative. The plant is found in India, Sri Lanka, topical regions of America & Malaysia. The aim of the present study was to carry out the preliminary phy…

Chaturvedi M et al, Formulation & Evaluation of Polyherbal Anthelmintic Preparation, Ethnobotanical Leaflets 13: 329-31. 2009.-ABSTRACT: The present study was done with the aim to formulate an anthelmintic preparation & to evaluate anthelmintic activity of formulation containing traditionally used herbs viz, Plumbago zeylanica (leaves), Hyoscyamus niger (roots) & Abutilon indicum (leaves) using adult earthworm Pheretima posthuma. The aqueous & ethanolic extract of the crude drug of different concentration were tested which involve determination of paralysis time & time to kill the worms. Pi…

Gupta D et al, EFFECT OF ETHANOLIC EXTRACTS OF ABUTILON INDICUM, ZEA MAYS & COMBINATION ON CALCIUM OXALATE UROLITHIASIS IN RAT, Jl of Drug Delivery & Therapeutics, 7(7):183-5, 2017 Abstract: In the present study the effect of calcium oxalate urolithiasis urinary risk factor of ethanolic extract of Abutilon indicum, Zea mays & their combination have been studied in albino rats. From this study it is deduced that the possible effect of the ethanolic extract of A indicum, Z mays & their combination can be assigned to be positive effect on the main urolithiasis risk factor,

Yasmin S et al, Antioxidant potential & radical scavenging effects of various extracts from Abutilon indicum & Abutilon muticum, Pharmaceut Biol, 48(3) : 282-289, 2010-Abstract: Abutilon indicum L. (Malvaceae) & Abutilon muticum DC. (Malvaceae) are traditional medicinal herbs used for analgesic, anthelmintic, hepatoprotective, & hypoglycemic properties. These effects may be correlated with the presence of antioxidant compounds. Extracts in organic solvents from the aerial parts & roots of both species were prepared & evaluated for their total antioxidant capacity (TAC), total phenolic conte…

Naik LS et al, antimicrobial activity & phytochemical analysis of Abutilon indicum leaf extract. Int. J. PharmTech Res, (1): 88-95.2015,

Rajesh J et al, FORMULATION, CHARACTERIZATION AND EVALUATION OF METHANOLIC EXTRACT OF ABUTILON INDICUM LOADED SOLID LIPID NANOPARTICLES AGAINST MICROORGANISMS CAUSING DIABETIC FOOT & URINARY TRACT INFECTION, Jl GTP Sci, 5(4) -(2014) 093–2102,

WAHAB S et al, The Structural, Biological, & In-Silico Profiling of Novel Capryloyl Tetra-Glucoside & Aliphatic Ester Constituents from the Abutilon indicum Offers New Perspectives on the Treatment of Pain & Inflammation, Plants (Basel), 11(19):2583, 2022-Abstract: Abutilon indicum L. (Malvaceae), more often referred to as Peeli booty, Kanghi, & Kakhi, is a perennial shrub found in many countries of Asia. Traditionally, this plant is used as a diuretic to treat inflammation, discomfort, urethral infections, & gout. Inflammation & pain are key topics of interest for researchers throughout th…

Adisakwattana S et al, Influence of the methanolic extract from Abutilon indicum leaves in normal & streptozotocin-induced diabetic rats, Afr Jl of Biotechnol, 8 (10) :2011-5, 2009,

Lakshmi S M et al, Protective Effect of Abutilon indicum L. (Malvaceae) Against Cisplatin Induced Nephrotoxicity in Rats, Innov Journal of Life Sci,

Ahmad J et al, Antioxidant Potential of Abutilon indicum (L.) Sw. Plant Pathol Microb, 2012, 3:3,

Ravi R et al, Anti-inflammatory Action of Abutilon indicum (L.) Sweet Leaves by HRBC Membrane Stabilization, Research Jl. Pharm. & Tech.2(2): 2009,

Archna S et al, Phytochemical & pharmacological profile of Abutilon indicum L. Sweet: à review. Int. Jl. Pharm. Sci. Rev. Res.; (1): 120-7.2013,

Mohite MS et al, Review on Pharmacological Properties of Abutilon indicum. Asian Jl. Pharm. Res. 2012; 2(4) :156-60,

Seetharam YN et al, Hypoglycemic activity of Abutilon indicum leaf extracts in rats, Fitoterapia. 73(2):156-9. 2002

Ambarsing et al, Chemical investigation & biological activity of phytoconstituents from methanol extract of Abutilon indicum leaves, Jl of Chem & Pharmaceut Res, 2012, 4(8):3959-65,

Kasthuri A et al, Adsorption of Chromium Ion by Acid Activated Abutilon Indicum-Kinetic, Mechanistic, Thermodynamic & Equilibrium Studies, Inter Jl of Current Res,

Paranjape AN et al, An EVALUATION OF ACUTE TOXICITY STUDY OF ROOT OF ABUTILON INDICUM [L] SWEET, Oriental Pharm & Experiment Med, 2006 6(4), 330-5,

Gaind KN et al, Phytochemical investigation of Abutilon indicum; Planta Med. 1976; 30(2):174-88.

Muthu C et al, Medicinal plants used by traditional healers in Kancheepuram District of Tamil Nadu, India, Jl of Ethno Biol & Ethnomed, 2006, 2:43-DOI: 10.1186/1746-4269-2-43

Tiwari S et al, identification of New Bioactive Compounds from Fruit of Abutilon indicum through GCMS Analysis, Biol Forum – An Inter Jl 8(1): 548-54, (2016,

Thakor P et al, Extraction & purification of phytol from Abutilon indicum: cytotoxic & apoptotic activity, RSC Adv., 2016,6-Abstract: Abutilon indicum is widely used as a medicinal plant in the Indian system of medicine. In the present study, we have evaluated the apoptosis inducing ability of leaf extract of AI. Hydromethanolic leaf extract showed cytotoxicity on Schizosaccharomyces pombe cells by affecting the growth & viability. Phytochemical analysis of the extract revealed the presence of secondary metabolites. A 2D TLC method was used for the separation of the active cytotoxic compoun…

Goyal N et al, Analgesic effects of various extracts of the root of Abutilon indicum Linn, Jl of Pharm & Bio Allied Sci, 1(1) :43-46, 2009,

Subramanian A et al, Larvicidal & adult emergence inhibition activity of Abutilon indicum (Linn.) (Malvaceae) leaf extracts against vector mosquitoes (Diptera: Culicidae), Jl of Biopesticides, 4 (1): 27 - 35 (2011)-Abstract: The crude leaf extracts of Abutilon indicum were evaluated for larvicidal, pupal deformities & adult emergence inhibition activity against vector mosquitoes viz., Aedes aegypti, Anopheles stephensi & Culex quinquefasciatus. Larvicidal activity was carried out using WHO protocol. Hexane extract with LC 50 value of 261.31 ppm after a period of 24 hr was found to be effect…

Kousalya M et al, EVALUATION OF ACUTE TOXICITY STUDY OF ROOT OF ABUTILON INDICUM [L] SWEET, INTER Jl OF FRONTIERS IN SC & Technol, 2 :3, 2014,

Saranya D et al, GC-MS & FT-IR Analyses of Ethyl-acetate Leaf extract of Abutilon indicum (L.) Sweet., Int. Jl. Adv. Res. Biol. Sci. 3(2): 193-7, 2013,

SARASWATHY R et al, PHYTO CHEMICAL INVESTIGATION, ANALGESIC & ANTI-INFLAMMATORY ACTIVITY OF ABUTILON INDICUM LINN, Inter Jl of Pharm & Pharmaceut Sci, 3, Suppl 2, 2011,

Kumar Giri R et al, Lipid lowering activity of Abutilon indicum (L.) leaf extracts in rats, Jl of Pharm Res, 2009, 2(11),1725-7,

Subramani R., Pharmacognostical phytochemical including GC-MS investigation of ethanolic leaf extracts of Abutilon indicum (Linn). Asian Jl. Pharm.Ana; (4): 88-92.2011-Abstract: Abutilon indicum (Linn) family (Malvaceae) popularly known as Atibala is used as one of the most important drugs in Traditional System of Medicine to treat various ailments. The plant is used due to its various properties as; demulcent, diuretics, anti-diabetic, anthelmintics, astringent, laxative, expectorant, antibacterial & antifungal activities. The Present research describes the simplest method of identificatio…

Krisanapun C et al, Aqueous extract of Abutilon indicum Sweet inhibits glucose absorption & stimulates insulin secretion in rodents, Nutr Res, 29(8) :579-87,

Mahanthesh MC et al, PHARMACOGNOSTICAL EVALUATION & ANTICONVULSANT ACTIVITY OF STEM OF ABUTILON INDICUM LINN SWEET, Int Jl of Pharm & Pharmaceut Sci, 8(8):58-70, 2016-Abstract: To investigate the pharmacognostical characteristics and in vivo anticonvulsant activity of chloroform, ethanol (90%) & aqueous extracts of Abutilon indicum stem. Methods: The AI stem were successively extracted using chloroform, ethanol & aqueous solvent (water). The extracts were screened for phytochemicals using HPTLC & GC-MS techniques. The extracts were also screened for acute toxicity & anticonvulsant activity,…

Chandrasekhar VM et al, Anti-diarrhoeal activity of Abutilon indicum Linn leaf extracts, Jl OF NAT REMEDIES, 4/1 (2004) 12-6-Abstract: The present study is aimed to evaluate the leaf extracts of Abutilon indicum for acclaimed anti-diarrhoeal activity using albino rats. Materials & methods: Anti-diarrhoeal activity of Abutilon indicum was evaluated by gastro intestinal motility, castor oil-induced diarrhoea & prostaglandin E 2 -induced enteropooling in rats. Loperamide was used as a standard drug. Results: The study revealed that, the methanolic extract & aqueous extract possessed significan…

Khanduri CN, Fertility Control of Female Rat Through Abutilon Indicum Seeds, INT Jl OF TECHNOL ENHANCEMENTS & EMERGING ENGINE RES, 2, :3 89 ISSN 2347-4289,

Golwala D.K et al, Anticonvulsant activity of Abutilon indicum leaf. Inter Jl of Pharm & Pharmaceut Sci, 2010; 2(1):66-71,

Khan MTJ et al, Antibacterial & Irritant Activities of Organic Solvent Extracts of Agave americana Linn., Albizzia lebbek Benth. Achyranthes aspera Linn. & Abutilon indicum Linn - a Preliminary Investigation. Pakistan Jl Zool. 2010; 42:93-7-Abstract: Hexane, chloroform & ethanol extracts of leaves of Agave americana L., seeds of Albizzia lebbek Benth & Achyranthes aspera L., & the whole plant of Abutilon indicum were tested for the antibacterial activity against Gram positive & Gram-negative bacteria. Ethanol & chlorofonn extracts of A americana & A aspera & ethanol extract of A lebbek exhi…

Sayeed R et al, Wound Healing activity of Abutilon Indicum, Pharmacogn Mag, 4:15, 2018-Abstract:  ethanolic extract of Abutilon indicum was studied for wound healing activity-using incision, excision & dead space wound models in albino rats. The ethanolic extract was studied at a dose of 400-mg/kg-body weight. Significant increase in wound contraction rate, skin breaking strength, granuloma strength & dry granuloma weight were studied. The decrease in epithelisation period was observed as compared to control & standard. The pro healing action may be due to increase in collagenation depositi…

Saini A et al, Evaluation of Root & Leaf Extract of Abutilon indicum Linn. for Antifungal activity, Inter Jl of Chem & Pharmaceut Sci, 2(3); 717-21, 2014,

Mat Åwska et al, Flavonoid compounds in the flowers of Abutilon indicum (L.) Sweet (Malvaceae). Acta Pol Pharm. 2002;59(3):227-9.

Chakraborty GS et al, Antinociceptive Activity OF Abutilon indicum (Linn) Sweet Stem Extracts, Arch Pharm Sci & Res, 2(1):241-5, 2010,

Bothara SB et al, Anti-Inflammatory Activity of Abutilon indicum Linn. Leaf, Res Jl Pharm & Tech, 3 :1, 2010-Abstract: The present study reveals that the ethanolic & aqueous extracts of Abutilon indicum Leaf using two different doses of each extract in acute (Carrageenin induced hind paw edema) and subacute (Formaldehyde induced hind paw edema) inflammation induced in rats, p.o. administration. In acute inflammation the % protection AIE 300 mg/kg-64.04 % & 100 mg/kg-59.55%, while AIA 300 mg/kg-46.66 % &100 mg/kg-32.88 %. In Subacute inflammation the % protection in 3 rd h are AIE 300 mg/kg-…

SUNIL M et al, Phytochemical Analysis & Antioxidant Evaluation of the Ethanolic Extract of the Leaves of Abutilon indicum, Cureus, 15(10): e47703, 2023-Abstract: in Indian traditional medicine, the Abutilon indicum plant, colloquially known as "Country mallow" or "Phuthi", has been vouched for its efficacy in treating conditions such as bronchitis & diabetes. The study aimed to explore the chemical constituents and antioxidant strength of the ethanolic extracts derived from the leaves of this plant (ELEAI). Objectives: To qualitatively pinpoint the phytochemicals in the ethanolic extract of…

Ponnudural K et al, EVALUATION OF ANTI - INFLAMMATORY ACTIVITY OF 75 PERCENT V/V METHANOLIC EXTRACT OF ABUTILON INDICUM (LINN.) SWEET LEAVES, Biol, 2011-Abstract: The active constituent of leaf extract of the plant (Abutilon indicum) contains various components such as essential oils in particular eugenol which is reported to possess antioxidant potential. Eugenol is the one of the constituents of plant under investigation. Therefore, based on the abo ve facts, it is clear that no scientific studies have been carried out in Abutilon indicum regarding the anti - inflammatory and gastro prote…

KRISANAPUN C, Thesis: HYPOGLYCEMIC EFFECT & MECHANISMS OF ACTION OF EXTRACT FROM ABUTILON INDICUM SWEET,

Gurumurthy H. et al. IN-VITRO ANTIBACTERIAL STUDY ON LEAF EXTRACTS OF ABUTILON INDICUM LINN. Eur J EAF Chem, 10(2) :1892-6, 2011,

Satish Kumar S et al, Evaluation of Analgesic & Anti-Inflammatory activity of Abutilon indicum, Intern Jl of Drug Devt & Res, 2013, 5(1): 99-102.

Shirish S et al, Evaluation of acute toxicity for Abutilon indicum, Der Pharmacia Lettre, 2011, 3(3):37-42,

Ranjan Kumar C et al, Lipid lowering activity of Abutilon indicum (L) leaf extracts in rats, Jl of Pharma Res, 2(11) :17-25, 2009-Abstract: Lipid lowering effect of the successive extracts of the leaf of Abutilon indicum (L.) was evaluated in triton & diet induced hyperlipidemic models of Wistar albino rats. The ethanolic & water extract at 400mg/kg dose levels inhibited the elevation in serum cholesterol & triglyceride levels on Triton WR 1339 administration rats. The extracts at the same dose level significantly attenuated the elevated serum total cholesterol & triglycerides with an incre…

Tirumalasetty J et al, Evaluation of Anti-anxiety Property of Alcoholic Extract of Abutilon indicum Leaves in Albino Mice, Int. Jl. Pharm. Phytopharmacol. Res. 2013; 2 (6): 397-399-Abstract: Various studies were conducted for anti-stress & antioxidant property of the plant Abutilon Indicum but not on anti-anxiety action. This study is done to elucidate the anti-anxiety property of the plant A Indicum. Alcoholic Extract of A Indicum leaves (AEAIL) were prepared using Soxhlet’s apparatus. Five groups of mice, each include five animals. Group I was taken as control and Normal saline was given …

ROSHENI N et al, EVALUATION OF ANTICATARACT POTENTIAL OF Abutilon indicum: AN IN Vitro STUDY, Indian Jl. Sci. Res. 7(1) : 81-84, 2216-abstract: Cataract, à leading cause of blindness & poor vision, is a major public health problem worldwide. Diabetes & hyperglycemia have long been recognized as risk factors for cataract. Because there is sufficient evidence that oxidative stress plays a role in the mechanisms of cataractogenesis, there is an increasing interest in developing suitable antioxidant nutrients, both of synthetic & plant origin that could be effective in delaying or preventing th…

Kaladhar D et al, Evaluation of Anti-inflammatory & Anti-proliferative Activity of Abutilon indicum L. Plant Ethanolic Leaf Extract on Lung Cancer Cell Line A549 for System Network Studies, Jl Cancer Sci Ther 6: 195-201-Abstract: In the present study, an evaluation was performed to know the anti-inflammatory-&-anti-proliferative activity-of ethanolic-leaf extract of Abutilon indicum for potential chemopreventive agent against lung cancer. Experimentation is also conducted on lung cancer cell line A549 along with interaction studies of Apaf-1 gene. The ethanolic leaf extract of A. indicum is…

Pattewar AM et al, COMPARATIVE EVALUATION OF IN-VITRO ANTIHELMINTHIC ACTIVITY OF DIFFERENT EXTRACTS OF ABUTILON INDICUM, Pharm Utility, 6: 3, 2012,

Pullaiah CP et al, SUPPLEMENTATION OF ETHANOLIC EXTRACT OF ABUTILON INDICUM (L) SWEET PREVENTS UROLITHIASIS IN EXPERIMENTAL RATS, Int Jl of Pharmacometrics & Integr BioSci, 1(1) :7-13, 2015.-Abstract: The present study was designed to evaluate the antiurolithiatic activity of Abutilon indicum extract in ethylene glycol (EG) & Vit. D 3 induced urolithiasis in rats. The protective effective of AI extract was studied in dose dependent manner by using 200mg/kg & 400mg/kg against ethylene glycol (EG) & Vit. D 3 induced urolithiasis in rats for 28 days. The antiurolithiatic effect was evaluated b…

Dashputre NL et al, Immunomodulatory Activity of Abutilon Indicum Linn on Albino Mice, Inter Jl of Pharm Sci & Res, 1(3) :178-84, 2010-Abstract: To study the immunomodulatory activity of aqueous & ethanol extracts of leaves of Abutilon indicum Linn. (Family: Malvaceae) on albino mice. Methods: The ethanolic & aqueous extract of leaves of A indicum was administered orally at the dosage levels of 200 mg/kg/day & 400 mg/kg/day body weight in mice. The assessment of immunomodulatory activity on specific & non-specific immunity were studied by heamagglutination antibody (HA) titer, delayed type …

Tripathi P et al, Anti-inflammatory activity of Abutilon indicum extract. Nat Prod Res. 2011-Abstract: Abutilon indicum Linn. had been broadly used for its reported biological activities in indigenous system of medicine. The ethanolic extract of the whole plant of A.I was evaluated for its anti-inflammatory activity at doses 250, 500 and 750 mg kg⁻¹ using the carrageenan-induced paw oedema in healthy Wistar albino rats. Results of in vivo activity led to the conclusion that the ethanolic extract of AI showed predominantly significant activity in a dose-dependent manner, which is comparable …

Ramasubramaniaraja R et al, Pharmacognostical phytochemical including GC-MS investigation of ethanolic extracts of Abutilon indicum-Linn, Asian Jl of Pharmaceut Analysis, 1:4, 2011-Abstract: Abutilon indicum popularly known as Atibala is used as one of the most important drugs in Traditional System of Medicine to treat various ailments. The plant is used due to its various properties as; demulcent, diuretics, anti-diabetic, anthelmintics, astringent, laxative, expectorant, antibacterial & antifungal activities. The Present research describes the simplest method of identification of phytoche…

Reddy U et al, PROTECTIVE EFFECT OF ABUTILON INDICUM L. (MALVACEAE) AGAINST ACETAMINOPHEN INDUCED NEPHROTOXICITY IN RATS, Home Arch, 1:2, 2013-Abstract: Acetaminophen overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms. The effects of ethanolic extract of Abutilon Indicum [200 mg per kg of body weight (mg/kg) & 400 mg/kg] on Acetaminophen induced nephrotoxicity were evaluated. Rats were divided into five groups containing 6 rats each. The control group received distilled water while other groups were treated with extract alone (400 mg/kg), Acetaminophen…

DHARMESH K et al, ANTICONVULSANT ACTIVITY OF ABUTILON INDICUM LEAF, Inter Jl of Pharm & Pharmaceut Sci, 2 :1, 2010,

Dashputre NL et al, Evaluation of Anti-Ulcer Activity of Methanolic Extract of Abutilon indicum Linn Leaves in Experimental Rats, Intern Jl of Pharmaceut Sci & Drug Res, 2011; 3(2): 97-100,

Sri Kumaran N et al, Biosynthesis of Silver nanoparticles Using Abutilon indicum (Link): An Investigation of Anti-Inflammatory and Antioxidant Potential Against Carrageenan Induced Paw Edema in Rats, Asian Jl of Pharmaceutics, 2017, 11(2),

Deshraj SC et al, ANTIBACTERIAL & ANTIFUNGAL ACTIVITY OF STEM BARK OF ABUTILON INDICUM (LINN.) SWEET, Int Jl of Pharmaceut Res & Devt, 2015-Abstract: Antibacterial and antifungal activity of methanolic extract of stem bark of A. indicum (10 mg/ml) was evaluated against Staphylococcus aureus, Escherichia coli and Candida albicans & Aspergillus niger respectively. Methanolic extract of AI stem bark showed significant antibacterial activity by showing zone of inhibition of 15.03 ± 0.05 & 12.36 ± 0.55 on nutrient agar medium plate against Staphylococcus aureus & Escherichia coli when compared t…

Padma Vairavasundaram R et al, Antimycotic activity of the components of Abutilon indicum (Malvaceae), Drug Invention Today 2009, 1(2),137-9,

Krisanapun C et al, Antidiabetic Activities of Abutilon indicum (L.) Sweet are Mediated by Enhancement of Adipocyte Differentiation & Activation of the GLUT1 Promoter, eCAM, doi:10.1093/eCAM/neq004,

Gharia A. K et al, Anthelmintic Activity of Some Essential Oils. Orient Jl Chem 2002;18(1)-Abstract: Essential oils are well known as flavouring agents. They are also widely studied in connection with their germicidal property against bacterial & fungal diseases. Essential oils also exhibit Anthelmintic activity. Here Anthelmintic activity of essential oils of Bothriocloa pertusa, Abutilon indicum, Xanthium strumarium, Mentha spicata, Cinnamomum Zeylanicum, Santalum album, Parthenium hysterophorus were studied on earth worm, tape worm, hook worm & nodular worm & was observed that essential …

Atul T, Study of some Essential Oil to show Antifungal activity with Special Reference to Abutilon Indicum & Lantana Camara, Res Jl of Pharmaceut Sci, 3(2), 1-2, 2014-Abstract: recent decades, antimicrobial plants gained a great importance because of increase resistance towards antibiotics acquired by various microorganisms by the use of EOs in both food & medicinal industries. EO sare the volatile substance which is normally formed as groups of cells which is found on any part of plant body. The function of EOs is exactly not well recognized but it was believed that i n t h i s a variety o…

Patil AS et al, Screening the In vitro Calcium Oxalate Crystal Inhibition Potential of Abutilon indicum L.: A Common Weed Plant from the Indian Medicine System, Austin Jl Biotechnol Bio-Eng. 2014;1(6): 4,

Ramesh B et al, ANTICANCER ACTIVITY OF GREEN SYNTHESIZED SILVER NANOPARTICLES OF ABUTILON INDICUM L. LEAF EXTRACT, Asian Jl of Phytomed & Clin Res. 3(4), 2015, 124 - 31.

Abdul M et al, Cytotoxic & Antimicrobial Activity of the Crude Extract of Abutilon Indicum, Inter Jl of Pharmacogn & Phytochem Res, 2(1);1-4, 2010,

Stefek M, Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract. Interdiscip.Toxicol, (2): 69-77. 2011,

Ahmed M et al, Analgesic principle from Abutilon indicum. Pharmazie. 2000; 55(4):314-6-Abstract: Bioactivity guided isolation of Abutilon indicum yielded eugenol [4-allyl-2-methoxyphenol], which was found to possess significant analgesic activity. At doses of 10, 30, & 50 mg/kg body weight, eugenol exhibited 21.30 (p < 0.05), 42.25 (p < 0.01) & 92.96% (p < 0.001) inhibition of acetic acid induced writhing in mice. At a dose of 50 mg/kg body weight, eugenol showed 33.40% (p < 0.05) prolontion of tail flicking time determined by the radiant heat method.

Rahuman AA et al, Isolation & identification of mosquito larvicidal compound from Abutilon indicum, Parasitol Res, 102 :5, 2008-DOI 10.1007/s00436-007-0864-5,

Khan RS et al, Cytotoxic constituents of Abutilon indicum leaves against U87MG human glioblastoma cells, Nat Prod Res 2015 25;29(11):1069-73. Epub 2014-Abstract: The study was aimed to identify cytotoxic leads from Abutilon indicum leaves for treating glioblastoma. The petroleum ether extract, methanol extract (AIM), chloroform & ethyl acetate sub-fractions (AIM-C and AIM-E, respectively) prepared from AIM were tested for cytotoxicity on U87MG human glioblastoma cells using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. These extracts exhibited considerable activity (IC…

Umamaheshwari M et al, Anticataract & antioxidant activities of Abutilon indicum Linn. against glucose-induced cataractogenesis using goat lenses. Jl. Nat. Prod. Plant Res; (1): 153-61. 2012-

Sammia Y et al, Antioxidant potential & radical scavenging effects of various extracts from Abutilon indicum & Abutilon muticum. Pharmaceut Biol, 2010;48(3):282-289.

Singh D et al, Modulatory Influence of Abutilon Indicum Leaves on Hepatic Antioxidant Status & Lipid Peroxidation against Alcohol-Induced Liver Damage in Rats, Pharmacologyonline 1: 253-62, 2008, Na

PORCHEZHIAN E, Hepatoprotective activity of Abutilon indicum on experimental liver damage in rats, Phytomed, 12(1):62-64-Abstract: The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- & paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- & paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination. The plant extract may interfere with free-radical formation, which may conclude in hepatoprotective action. Acute t…