Achyranthes aspera (Mounted Kavalié) : medicinal properties in alcoholic extraction

Achyranthes aspera (Mounted Kavalié, Kolan, Jandam, Mounted Cavalier, Tights, constable, Kavalié-monté, Cavalier-monté, Collant, gendarme) — family Amaranthacées.

Scientific synonyms : Achyranthes aspera var. aspera Auct, A. aspera var. argebtea-Griseb, A. argentea sensu Duss, A. fructicosa Lam, var. pubescens-Moq in DC, Centrostachys aspera-(L)-Stand..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 22 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 107 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Hepatitis, cirrhosis, normalisation of liver function tests: SGPT, SGOT, SALP, GGT, bilirubin, LPO

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kartik R (2010)

     Excerpt Administration of AAE suppressed hepatic diagnostic and oxidative stress markers as revealed by decrease in NDEA & CCl (4) -induced elevated levels of SGPT, SGOT, SALP, GGT, bilirubin, & LPO. In this study, we assessed the antioxidant potential and suppressive effects of Achyranthes aspera by evaluating the hepatic diagnostic markers on chemical-induced hepatocarcinogenesis.

   • According to Tahiliani A (2000)

     Excerpt A study was made to evaluate the role of Achyranthes aspera on the changes in serum thyroid hormone concentrations & glucose levels in male rats. The effects of the extract on body weight, hepatic protein content, lipid peroxidation (LPO), superoxide dismutase (SOD) & catalase (CAT) activities & on serum triiodothyronine (T3), thyroxine (T4) & glucose levels were evaluated.

   • According to Manjunatha BK (2012)

     Excerpt Manjunatha BK et al: Hepatoprotective Potency of Achyranthes aspera: An In-vivo Study.

   • According to Chakrabarti R (2012)

     Excerpt Immunostimulatory & growth promoting properties of Achyranthes aspera seeds were studied with larvae of common carp Cyprinus carpio. SGOT a&SGPT levels were significantly (P < 0.05) higher in control group compared to the treated groups.

   • According to Goyal BR (2008)

     Excerpt In the present investigation, we have studied the bronchoprotective effect of ethanolic extract of Achyranthes aspera Linn in toluene isocyanate (TDI) induced occupational asthma in Wistar rats. Liver homogenate was utilized for assessment of oxidative stress and lung histological examination was performed to investigate the inflammatory status in the airway.

2. 2

   Type II diabetes mellitus

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to KUMAR A (2011)

     Excerpt The ethanolic leaves extract of Achyranthes aspera was evaluated for in-vivo antidiabetic activity against Streptozotocin induced diabetic rats. In the present study we have tried to evaluate hypoglycemic effects of Achyranthes aspera (Apamarga) in Streptozotocin induced hyperglycemia.

   • According to Mandar Z (2011)

     Excerpt Decreased Hb% & O2 carrying capacity of blood in diabetes further hamper the diabetic wound healing; hence the actions of AA on haemopoietic system may complement its hypoglycemic & antihyperlipidemic activity in control of diabetes & its complications. However, literature search in this direction failed to give any report on its haematinic activity; hence focus of present study was to explore actions of AA on haemopoietic system of alloxan induced diabetic rats.

   • According to Author (2016)

     Excerpt aspera has potent antidiabetic effect in alloxan induced diabetic mice & could therefore be used as a remedy for the treatment of diabetes mellitus. Achyranthes aspera is an annual, stiff erect herb, about 0.3 to 0.9m high & found commonly as a weed throughout India.

   • According to Xue S (2009)

     Excerpt Xue S et al: Protective effect of sulfated Achyranthes bidentata Blume polysaccharides on streptozotocin induced oxidative stress in rats.

   • According to Uma B (n.d.)

     Excerpt Achyranthes Aspera Linn known as Chirchira (Hindi), Agadha (Marathi) is an indigenous herb found in India. The herb has been reported to have variety of activities like antifertility, antihyperlipidemic, antidiabetic, immunomodulatory, Anticarcinogenic, diuretic & cardiotonic, analgesic, anti-inflammatory, hypnotic, antifungal & antibacterial activity.

3. 3

   Cancer: adjuvant treatment of colorectal and liver carcinoma

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kartik R (2010)

     Excerpt In this study, we assessed the antioxidant potential and suppressive effects of Achyranthes aspera by evaluating the hepatic diagnostic markers on chemical-induced hepatocarcinogenesis. The hepatic diagnostic markers namely serum glutamic Oxaloacetic transaminase (AST), serum glutamic pyruvate transaminase (ALT), serum alkaline phosphatase (ALP), gamma glutamyl transpeptidase (GGT), & bilirubin (BL) were also assayed, a& the histopathological studies were investigated in control, positive control, and experimental groups.

   • According to Tahiliani A (2000)

     Excerpt A study was made to evaluate the role of Achyranthes aspera on the changes in serum thyroid hormone concentrations & glucose levels in male rats. The effects of the extract on body weight, hepatic protein content, lipid peroxidation (LPO), superoxide dismutase (SOD) & catalase (CAT) activities & on serum triiodothyronine (T3), thyroxine (T4) & glucose levels were evaluated.

   • According to Manjunatha BK (2012)

     Excerpt Manjunatha BK et al: Hepatoprotective Potency of Achyranthes aspera: An In-vivo Study.

   • According to SINGH S (2017)

     Excerpt 70% Ethanolic plant root extract of Achyranthes aspera showed Invitro anticancer activity against different human cancer cell lines such as liver & colon. The in-vitro test was performed against two human cancer cell lines namely liver (Hep-2) & colon (HT-29).

   • According to BACHIR H (2024)

     Excerpt RESEARCH HIGHLIGHTS: AA leaves have various phytochemicals which contribute to its medicinal properties Various extracts of the leaves of A.A possess antioxidant, antimitotic & antiproliferative potential The results of the study indicated that the leaves extract of A.A have strong potential to be used as a source of anti-cancer agent. The present research work was conducted to investigate the anticancer potential of AA leaves by focusing on the antioxidant, antiproliferative & antimitotic activities of leaf extracts.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.