Adenium obesum (Desert Rose) : medicinal properties in alcoholic extraction
Adenium obesum (Desert Rose, Rose du désert) — family Apocynacées.
Scientific synonyms : Adenium arabicum Balf.f., A-arboreum Ehrenb., A coetaneum Stapf A socotranum Vierh., A somalense Balf.f., A speciosum Fenzl, A tricholepis Chiov., Cameraria obesa (Forssk.) Spreng., Neriium obesum Forssk..
This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 34 scientific references for this species (full detail in the application).
Therapeutic indications in alcoholic extraction:
Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).
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Cancer: adjuvant treatment of carcinoma: lung, nasopharyngeal squamous cell carcinoma
Scientific references (short excerpts)
Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
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According to Hoffman JJ (1977)
Excerpt An ethanol extract of Adenium obesum exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx test system.
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According to Alsherhri A (2022)
Excerpt In addition, we also evaluated the anticancer activity of AOE, & it was observed that AOE was found to be cytotoxic against A549 lung cancer cells. Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications.
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According to Alsherhri A (2022)
Excerpt In addition, we also evaluated the anticancer activity of AOE, & it was observed that AOE was found to be cytotoxic against A549 lung cancer cells. Adenium obesum commonly known as “desert rose” belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications.
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According to Abul Farah M (2016)
Excerpt Adenium obesum is a plant of the family Apocynaceae that is rich in toxic cardiac glycosides; however, there is scarce information on the anticancer potential of its AgNPs. The biological properties of novel AOAgNPs were investigated on MCF-7 breast cancer cells.
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According to Qasem A Ali (2019)
Excerpt The extracts prepared from various areal parts of the Adenium obesum (Forssk.) Roem. The above findings indicate that AO ethanolic seeds extracts has cyto-genotoxic properties that could be further explored for the potential source of chemotherapeutic lead against cancer,.
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According to Hoffman JJ (1977)
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Osteoarthritis, arthritis, rheumatism, oedema
Scientific references (short excerpts)
Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
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According to Alsherhri A (2022)
Excerpt Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. Furthermore, ethanolic AOE demonstrated the anti-inflammatory potential of AOE in murine alveolar macrophages (J774A.1) as an in vitro model system.
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According to Alsherhri A (2022)
Excerpt Adenium obesum commonly known as “desert rose” belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. Furthermore, ethanolic AOE demonstrated the anti-inflammatory potential of AOE in murine alveolar macrophages (J774A.1) as an in vitro model system.
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According to Mouza KG et al (2015)
Excerpt To prepare different polarities crude extracts from the roots of Adenium obesum (AO) and to evaluate their total phenolics, total flavonoids & antioxidant activity by Folin-Ciocalteu reagent, aluminum chloride & 1, 1-diphenyl-2-picrylhydrazyl (DPPH) methods.
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According to Kiyohara H (2012)
Excerpt The results indicated that the extracts of Adenium obesum & Tephrosia nubica possessed antiviral activity (99.3 & 93.3% inhibition at the concentration of 10 μg/ml, respectively).
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According to Alsherhri A (2022)
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Oxidative stress
Scientific references (short excerpts)
Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
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According to Ebrahim N (2013)
Excerpt The aim of this study was to investigate & compare Adenium obesum L. Also, there is a good correlation between antioxidant activity (R2 = 0.9368) for water/ethanol series extracts,.
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According to Sulelman MHA (2021)
Excerpt Acacia seyal & Adenium obesum are used in traditional medicines by indigenous communities of the Asir region of Saudi Arabia. The antioxidant capacities in DPPH, H2O2, & FRAP assay & the TPC & TFC were determined by spectrophotometry, & their correlation with the IC50 of the DPPH & H2O2 & the EC50 of the FRAP capacities were analyzed by Pearson’s correlation.
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According to Alsherhri A (2022)
Excerpt Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. The antioxidant potential of ethanolic extract of AOE was examined by different antioxidant assays, such as antioxidant capacity by the DPPH, ABTS, superoxide, hydroxyl radical scavenging, & lipid peroxidation inhibition assays.
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According to Kershi RM (2014)
Excerpt Also, there is a good correlations between antioxidant activity (R2 = 0.9368) for water/ethanol series extracts.,. The extracts were analyzed for monomeric anthocyanins contents & antioxidant activities.
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According to Mouza KG et al (2015)
Excerpt To prepare different polarities crude extracts from the roots of Adenium obesum (AO) and to evaluate their total phenolics, total flavonoids & antioxidant activity by Folin-Ciocalteu reagent, aluminum chloride & 1, 1-diphenyl-2-picrylhydrazyl (DPPH) methods. In the case of antioxidant activity of different crude extracts from AO, by Soxhlet method, the highest one was equivalent to DPPH in methanol & the lowest one was in butanol.
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According to Ebrahim N (2013)
Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.
Evolution of this plant record
Under the CTA · public change history
+7 references · −7 references
Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Full bibliographic texts for new, corrected, or removed references expand below.
+7 references — show text
ENEOJO SA et al, Toxicological Evaluation of Ethanol Extract of Adenium obesum Stem Bark in African Catfish, Clarias gariepinus J. Appl. Sci. Environ. Manage. 18 (1) 49-52, 2014-Abstract: The toxicity of ethanol extract of Adenium obesum stem bark as a tool for aquaculture pond management prior to the stocking of desired fish species was evaluated in Clarias gariepinus over a 96-h exposure. The fish were exposed to 6.25 mgL-1, 7.50 mgL ⁻¹, 8.20 mgL ⁻¹, 8.80 mgL ⁻¹ & 10.00 mgL ⁻¹ of the extract & a control in an acute static toxicity bioassay after performing a range finding test to determin…
AddedHossain MA et al, A comparison of the antimicrobial effectiveness of different polarities crude extracts from the leaves of Adenium obesum used in Omani traditional medicine for the treatment of microbial infections, Asian Pac J of Trop Disease, 4(2):5934-7, 2014-Abstract: To study & compare different crude extracts from the leaves of Adenium obesum for antimicrobial potency & to perform different group tests. Methods: After processed, the leaves samples were used for extraction with methanol solvent by Soxhlet extraction method. The methanol crude extract was prepared by evaporating the so…
AddedEneojo SA et al, Hepatotoxicity of Ethanol Extract of Adenium obesum Stem Bark in Wistar Rats British J of Pharmaceut Res, 4(9): 1041-52, 2014-Abstract: Adenium obesum is a known medicinal plant thereby creating the need for the evaluation of its toxicity and histopathological effects on the liver of female Wistar rats orally administered ethanol extract of the plant’s stem bark. Place & Duration of Study: Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Nigeria, between January 2011 & January 2012. Methodology: Ethanol extraction of AO stem bark was performed prior to sc…
AddedEneojo SA et al, Haematotoxicity of ethanol extract of Adenium obesum (Forssk) Roem & Schult stem bark in Wistar rats, Trop Jl of Pharm Res, 13(11)1896, 2014-Abstract: To investigate the acute toxicity of ethanol extract of Adenium obesum stem bark in Wistar rats in relation to haematological parameters. Methods: This involved the administration of single dose of 300 mgkg-1, 2000 mgkg-1 & 5000 mgkg-1 of the extract by oral gavage separately to three different groups of female rats (n = 3) one after another based on the absence of mortality and/or morbidity during a 14-day observation perio…
AddedAlsherhri A et al, in-Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 13:847534, 2022-Abstract: Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC-MS) to identify the important phytochemical compounds. The GC-MS a…
AddedAlsherhri A et al, In Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 2022-Abstract: Adenium obesum commonly known as “desert rose” belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC–MS) to identify the important phytochemical compounds. The GC–MS analysis of …
AddedHossain MA et al, Evaluation of different extraction methods on antimicrobial potency of Adenium obesum stem against food borne pathogenic bacterial strains in Oman, Asian Pac Jl of Trop Disease, 4(2):5985-9, 2014-Abstract: To determine & compare the effect on antimicrobial potency of crude stems extract of Adenium obesum by Soxhlet & maceration extraction methods. Methods: The crude extracts were prepared from the coarse samples of stems with methanol by using Soxhlet & maceration extraction methods. Both the crude extracts from two extraction methods were dissolved in water & successively…
AddedENEOJO SA et al, Toxicological Evaluation of Ethanol Extract of Adenium obesum Stem Bark in African Catfish, Clarias gariepinus J. Appl. Sci. Environ. Manage. 18 (1) 49-52, 2014-Abstract: The toxicity of ethanol extract of Adenium obesum stem bark as a tool for aquaculture pond management prior to the stocking of desired fish species was evaluated in Clarias gariepinus over a 96-h exposure. The fish were exposed to 6.25 mgL-1, 7.50 mgL ⁻¹, 8.20 mgL ⁻¹, 8.80 mgL ⁻¹ & 10.00 mgL ⁻¹ of the extract & a control in an acute static toxicity bioassay after performing a range finding test to determin…
RemovedHossain MA et al, A comparison of the antimicrobial effectiveness of different polarities crude extracts from the leaves of Adenium obesum used in Omani traditional medicine for the treatment of microbial infections, Asian Pac J of Trop Disease, 4(2):5934-7, 2014-Abstract: To study & compare different crude extracts from the leaves of Adenium obesum for antimicrobial potency & to perform different group tests. Methods: After processed, the leaves samples were used for extraction with methanol solvent by Soxhlet extraction method. The methanol crude extract was prepared by evaporating the so…
RemovedEneojo SA et al, Hepatotoxicity of Ethanol Extract of Adenium obesum Stem Bark in Wistar Rats British J of Pharmaceut Res, 4(9): 1041-52, 2014-Abstract: Adenium obesum is a known medicinal plant thereby creating the need for the evaluation of its toxicity and histopathological effects on the liver of female Wistar rats orally administered ethanol extract of the plant’s stem bark. Place & Duration of Study: Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Nigeria, between January 2011 & January 2012. Methodology: Ethanol extraction of AO stem bark was performed prior to sc…
RemovedEneojo SA et al, Haematotoxicity of ethanol extract of Adenium obesum (Forssk) Roem & Schult stem bark in Wistar rats, Trop Jl of Pharm Res, 13(11)1896, 2014-Abstract: To investigate the acute toxicity of ethanol extract of Adenium obesum stem bark in Wistar rats in relation to haematological parameters. Methods: This involved the administration of single dose of 300 mgkg-1, 2000 mgkg-1 & 5000 mgkg-1 of the extract by oral gavage separately to three different groups of female rats (n = 3) one after another based on the absence of mortality and/or morbidity during a 14-day observation perio…
RemovedAlsherhri A et al, in-Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 13:847534, 2022-Abstract: Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC-MS) to identify the important phytochemical compounds. The GC-MS a…
RemovedAlsherhri A et al, In Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 2022-Abstract: Adenium obesum commonly known as “desert rose” belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC–MS) to identify the important phytochemical compounds. The GC–MS analysis of …
RemovedHossain MA et al, Evaluation of different extraction methods on antimicrobial potency of Adenium obesum stem against food borne pathogenic bacterial strains in Oman, Asian Pac Jl of Trop Disease, 4(2):5985-9, 2014-Abstract: To determine & compare the effect on antimicrobial potency of crude stems extract of Adenium obesum by Soxhlet & maceration extraction methods. Methods: The crude extracts were prepared from the coarse samples of stems with methanol by using Soxhlet & maceration extraction methods. Both the crude extracts from two extraction methods were dissolved in water & successively…
RemovedFirst public publication
+1 indication · −1 indication · +7 references · −7 references
Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Full bibliographic texts for new, corrected, or removed references expand below.
+7 references — show text
ENEOJO SA et al, Toxicological Evaluation of Ethanol Extract of Adenium obesum Stem Bark in African Catfish, Clarias gariepinus J. Appl. Sci. Environ. Manage. 18 (1) 49-52, 2014-Abstract: The toxicity of ethanol extract of Adenium obesum stem bark as a tool for aquaculture pond management prior to the stocking of desired fish species was evaluated in Clarias gariepinus over a 96-h exposure. The fish were exposed to 6.25 mgL-1, 7.50 mgL ⁻¹, 8.20 mgL ⁻¹, 8.80 mgL ⁻¹ & 10.00 mgL ⁻¹ of the extract & a control in an acute static toxicity bioassay after performing a range finding test to determin…
AddedHossain MA et al, A comparison of the antimicrobial effectiveness of different polarities crude extracts from the leaves of Adenium obesum used in Omani traditional medicine for the treatment of microbial infections, Asian Pac J of Trop Disease, 4(2):5934-7, 2014-Abstract: To study & compare different crude extracts from the leaves of Adenium obesum for antimicrobial potency & to perform different group tests. Methods: After processed, the leaves samples were used for extraction with methanol solvent by Soxhlet extraction method. The methanol crude extract was prepared by evaporating the so…
AddedEneojo SA et al, Hepatotoxicity of Ethanol Extract of Adenium obesum Stem Bark in Wistar Rats British J of Pharmaceut Res, 4(9): 1041-52, 2014-Abstract: Adenium obesum is a known medicinal plant thereby creating the need for the evaluation of its toxicity and histopathological effects on the liver of female Wistar rats orally administered ethanol extract of the plant’s stem bark. Place & Duration of Study: Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Nigeria, between January 2011 & January 2012. Methodology: Ethanol extraction of AO stem bark was performed prior to sc…
AddedEneojo SA et al, Haematotoxicity of ethanol extract of Adenium obesum (Forssk) Roem & Schult stem bark in Wistar rats, Trop Jl of Pharm Res, 13(11)1896, 2014-Abstract: To investigate the acute toxicity of ethanol extract of Adenium obesum stem bark in Wistar rats in relation to haematological parameters. Methods: This involved the administration of single dose of 300 mgkg-1, 2000 mgkg-1 & 5000 mgkg-1 of the extract by oral gavage separately to three different groups of female rats (n = 3) one after another based on the absence of mortality and/or morbidity during a 14-day observation perio…
AddedAlsherhri A et al, in-Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 13:847534, 2022-Abstract: Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC-MS) to identify the important phytochemical compounds. The GC-MS a…
AddedAlsherhri A et al, In Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 2022-Abstract: Adenium obesum commonly known as “desert rose” belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC–MS) to identify the important phytochemical compounds. The GC–MS analysis of …
AddedHossain MA et al, Evaluation of different extraction methods on antimicrobial potency of Adenium obesum stem against food borne pathogenic bacterial strains in Oman, Asian Pac Jl of Trop Disease, 4(2):5985-9, 2014-Abstract: To determine & compare the effect on antimicrobial potency of crude stems extract of Adenium obesum by Soxhlet & maceration extraction methods. Methods: The crude extracts were prepared from the coarse samples of stems with methanol by using Soxhlet & maceration extraction methods. Both the crude extracts from two extraction methods were dissolved in water & successively…
AddedENEOJO SA et al, Toxicological Evaluation of Ethanol Extract of Adenium obesum Stem Bark in African Catfish, Clarias gariepinus J. Appl. Sci. Environ. Manage. 18 (1) 49-52, 2014-Abstract: The toxicity of ethanol extract of Adenium obesum stem bark as a tool for aquaculture pond management prior to the stocking of desired fish species was evaluated in Clarias gariepinus over a 96-h exposure. The fish were exposed to 6.25 mgL-1, 7.50 mgL ⁻¹, 8.20 mgL ⁻¹, 8.80 mgL ⁻¹ & 10.00 mgL ⁻¹ of the extract & a control in an acute static toxicity bioassay after performing a range finding test to determin…
RemovedHossain MA et al, A comparison of the antimicrobial effectiveness of different polarities crude extracts from the leaves of Adenium obesum used in Omani traditional medicine for the treatment of microbial infections, Asian Pac J of Trop Disease, 4(2):5934-7, 2014-Abstract: To study & compare different crude extracts from the leaves of Adenium obesum for antimicrobial potency & to perform different group tests. Methods: After processed, the leaves samples were used for extraction with methanol solvent by Soxhlet extraction method. The methanol crude extract was prepared by evaporating the so…
RemovedEneojo SA et al, Hepatotoxicity of Ethanol Extract of Adenium obesum Stem Bark in Wistar Rats British J of Pharmaceut Res, 4(9): 1041-52, 2014-Abstract: Adenium obesum is a known medicinal plant thereby creating the need for the evaluation of its toxicity and histopathological effects on the liver of female Wistar rats orally administered ethanol extract of the plant’s stem bark. Place & Duration of Study: Department of Veterinary Pathology, Ahmadu Bello University, Zaria, Nigeria, between January 2011 & January 2012. Methodology: Ethanol extraction of AO stem bark was performed prior to sc…
RemovedEneojo SA et al, Haematotoxicity of ethanol extract of Adenium obesum (Forssk) Roem & Schult stem bark in Wistar rats, Trop Jl of Pharm Res, 13(11)1896, 2014-Abstract: To investigate the acute toxicity of ethanol extract of Adenium obesum stem bark in Wistar rats in relation to haematological parameters. Methods: This involved the administration of single dose of 300 mgkg-1, 2000 mgkg-1 & 5000 mgkg-1 of the extract by oral gavage separately to three different groups of female rats (n = 3) one after another based on the absence of mortality and/or morbidity during a 14-day observation perio…
RemovedAlsherhri A et al, in-Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 13:847534, 2022-Abstract: Adenium obesum commonly known as "desert rose" belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC-MS) to identify the important phytochemical compounds. The GC-MS a…
RemovedAlsherhri A et al, In Vitro Evaluation of Antioxidant, Anticancer, & Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum, Front Pharmacol, 2022-Abstract: Adenium obesum commonly known as “desert rose” belongs to the family Apocynaceae & has previously been reported for its anti-influenza, antimicrobial, & cytotoxic efficacies & well-known for their ethno-medicinal applications. In the present study, ethanolic extracts of A. obesum (AOE) were analyzed by gas chromatography-mass spectrometry (GC–MS) to identify the important phytochemical compounds. The GC–MS analysis of …
RemovedHossain MA et al, Evaluation of different extraction methods on antimicrobial potency of Adenium obesum stem against food borne pathogenic bacterial strains in Oman, Asian Pac Jl of Trop Disease, 4(2):5985-9, 2014-Abstract: To determine & compare the effect on antimicrobial potency of crude stems extract of Adenium obesum by Soxhlet & maceration extraction methods. Methods: The crude extracts were prepared from the coarse samples of stems with methanol by using Soxhlet & maceration extraction methods. Both the crude extracts from two extraction methods were dissolved in water & successively…
Removed