Aframomum melegueta (Pwèv-Djinen) : medicinal properties in alcoholic extraction

Aframomum melegueta (Pwèv-Djinen, Malagèt, Guinea pepper, Malaguette, Poivre de Guinée) — family Zingiberacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 55 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Plant fungi: carrot: Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum, Penicillium expansum

   Plant part used: SHEET.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Okoi AI (2013)

     Excerpt The microbial pathogens isolated were Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum and Penicillium expansum. The bioactive & antifungal effects of ethanol extracts of Aframomum melegueta and Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots.

   • According to Fasoyiro S (2007)

     Excerpt Fasoyiro S et al, Phytochemical characterization d the antimicrobial property of Aframomum danielli extract.

   • According to Akindele O (2022)

     Excerpt Bryophyllum pinnatum, Aframomum melegueta, Garcinia kola, Sphenocentrum jollyanum, Adansonia digitata, Sutherlandia frutescens, Hibiscus sabdariffa, Moringa oleifera, & Nigella sativa possess a combination of antiviral, immunomodulatory, anti-inflammatory, & COVID-19 symptoms relieving activities. The study provides baseline information on the pharmacological activities, toxicity, & chemical components of 9 African medicinal plants with antiviral, immunomodulatory, anti-inflammatory, & symptoms relieving activities, thereby making the plants candidates for further investigation for effectiveness against COVID-19,.

   • According to OGODO AC (2017)

     Excerpt The antibacterial & Antimycotic activity of Aframomum melegueta seeds were investigated against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella species, Klebsiella species, Bacillus species, Fusarium species, Rhizopus species, Aspergillus species, Penicillium species & Mucor species isolated from spoiled bread & tomatoes using agar well diffusion method. The antifungal activity showed that Rhizopus sp was the most inhibited by both ethanol & aqueous extracts respectively (20mm & 16mm), followed Penicillium sp.

   • According to Okigbo RN (2006)

     Excerpt flavus, Fusarium oxysporum Rhizopus stolonifer, Botryodiplodia theobromae & Penicillium chrysogenum. Effects of leaf extracts of Ocimum gratissimum & Aframomum melegueta on spore germination & mycelial reduction of the most occurring fungal pathogen causing soft rot of Yam tuber were investigated.

2. 2

   Fungal infection: Fusarium sp., Rhizopus sp., Aspergillus sp., Penicillium sp., Mucor sp.

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Okoi AI (2013)

     Excerpt The bioactive & antifungal effects of ethanol extracts of Aframomum melegueta and Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots. The microbial pathogens isolated were Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum and Penicillium expansum.

   • According to OGODO AC (2017)

     Excerpt The antibacterial & Antimycotic activity of Aframomum melegueta seeds were investigated against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella species, Klebsiella species, Bacillus species, Fusarium species, Rhizopus species, Aspergillus species, Penicillium species & Mucor species isolated from spoiled bread & tomatoes using agar well diffusion method. aeruginosa, Klebsiella sp, Penicillium sp & Rhizopus sp have 20mg/mL, Fusarium sp, Aspergillus sp & Mucor sp have 30mg/mL while Bacillus sp was the most susceptible with MIC of 5mg/mL.

   • According to Fasoyiro S (2007)

     Excerpt Fasoyiro S et al, Phytochemical characterization d the antimicrobial property of Aframomum danielli extract.

   • According to Akindele O (2022)

     Excerpt Bryophyllum pinnatum, Aframomum melegueta, Garcinia kola, Sphenocentrum jollyanum, Adansonia digitata, Sutherlandia frutescens, Hibiscus sabdariffa, Moringa oleifera, & Nigella sativa possess a combination of antiviral, immunomodulatory, anti-inflammatory, & COVID-19 symptoms relieving activities. The study provides baseline information on the pharmacological activities, toxicity, & chemical components of 9 African medicinal plants with antiviral, immunomodulatory, anti-inflammatory, & symptoms relieving activities, thereby making the plants candidates for further investigation for effectiveness against COVID-19,.

   • According to Okigbo RN (2006)

     Excerpt Effects of leaf extracts of Ocimum gratissimum & Aframomum melegueta on spore germination & mycelial reduction of the most occurring fungal pathogen causing soft rot of Yam tuber were investigated. flavus, Fusarium oxysporum Rhizopus stolonifer, Botryodiplodia theobromae & Penicillium chrysogenum.

3. 3

   Bacterial infection: Bacillus sp., Klebsiella spp., Salmonella spp., E. coli, Pseudomonas aeruginosa, Shigella spp., Staphylococcus aureus

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to OGODO AC (2017)

     Excerpt The antibacterial & Antimycotic activity of Aframomum melegueta seeds were investigated against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella species, Klebsiella species, Bacillus species, Fusarium species, Rhizopus species, Aspergillus species, Penicillium species & Mucor species isolated from spoiled bread & tomatoes using agar well diffusion method. The result showed that the ethanol extract exhibited higher antibacterial activity more than the aqueous extract with Bacillus sp having the highest zone of inhibition (28mm, 23mm), followed by Salmonella sp.

   • According to Okoi AI (2013)

     Excerpt The bioactive & antifungal effects of ethanol extracts of Aframomum melegueta and Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots. melegueta, indicating high antifungal potency of the plants.

   • According to Fasoyiro S (2007)

     Excerpt Fasoyiro S et al, Phytochemical characterization d the antimicrobial property of Aframomum danielli extract.

   • According to Akindele O (2022)

     Excerpt Bryophyllum pinnatum, Aframomum melegueta, Garcinia kola, Sphenocentrum jollyanum, Adansonia digitata, Sutherlandia frutescens, Hibiscus sabdariffa, Moringa oleifera, & Nigella sativa possess a combination of antiviral, immunomodulatory, anti-inflammatory, & COVID-19 symptoms relieving activities. The study provides baseline information on the pharmacological activities, toxicity, & chemical components of 9 African medicinal plants with antiviral, immunomodulatory, anti-inflammatory, & symptoms relieving activities, thereby making the plants candidates for further investigation for effectiveness against COVID-19,.

   • According to DOHERTY VF (2010)

     Excerpt Antibacterial activity of Aframomum melegueta was tested on salmonella spp, Escherichia coli, Shigella spp & Klebsiella spp. coli & Shigella spp are 30mm, 15mm, 20mm, & 15mm respectively with ethanolic extract.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.