Agave americana (Ox tongue) : medicinal properties in alcoholic extraction

Agave americana (Ox tongue, Sachparèy, Sarsaparilla, Lang bèf, Langue-à-bœuf, Salsepareille) — family Agavacées.

Scientific synonyms : Agave altissima name Zumagl., A complicata Trel. ex Ochot., A cordillerensis Lodé & Pino, A felina Trel., A fuerstengergii Hacobi, A gracilispina (Rol.-Goss.) Engelm. ex Trel., Aingens A.Berger, A melliflua Trel..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 50 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Shegute T (2020)

     Excerpt Purpose: To determine the phytochemical constituents & in vitro antibacterial activity of leaf extracts of AA against Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella species, & Escherichia coli. americana leaf extracts on selected bacterial strains & to determine the phytochemical components.

   • According to Khan MTJ (2010)

     Excerpt Vacuum liquid chromatography isolated fractions from chloroform extract of A aspera displayed antibacterial activity against Bacillus subtilis, Escherichia coli & Pseudomonas aeruginosa. Hexane, chloroform & ethanol extracts of leaves of Agave americana L., seeds of Albizzia lebbek Benth & Achyranthes aspera L., & the whole plant of Abutilon indicum were tested for the antibacterial activity against Gram positive & Gram-negative bacteria.

   • According to Sahnoun M (2018)

     Excerpt Agave americana extract was analyzed by reverse phase HPLC for characterization. These findings provided a rational reason to establish apigenin capability as a therapeutic target for postprandial hyperglycaemia modulation & antifungal therapy.

   • According to Sahnoun M (2019)

     Excerpt Among phenolic compounds, Agave americana L. These findings provided a rational reason to establish the isolated compounds capability as therapeutic target for hyperglycaemia modulation & antifungal therapy.

   • According to Parmar VS (1992)

     Excerpt Parmar VS et al, New antibacterial tetra triacontanol derivatives from Agave americana L., Tetrahedron, 48(7):1281-4, 1992-/doi:10.1016/S0040-4020(01)90790-2-.

2. 2

   Cancer: adjuvant treatment for ovarian carcinoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Shireen F (2022)

     Excerpt Green silver nanoparticles (AgNPs) & crude ethanolic, methanolic, aqueous, & acetonic extracts from leaves of Agave americana, Mentha spicata, & Mangifera indica were scrutinized for possible antineoplastic & cytotoxic efficacy. americana revealed good antineoplastic activity (69%).

   • According to Khade KV (2015)

     Excerpt The present study was designed to determine the anticancer activity of the ethanolic extract of leaves of Agave americana L. MTT assay have been utilised to measure the antitumor activity of ethanolic extract of AA leaves by using PA-1 human cell line of ovarian teratocarcinoma.

   • According to Vaghela HN (2024)

     Excerpt The aim of this study was to formulate Phytosomes with antioxidant & SPF activity using ethanolic extracts of Agave americana-americana & AAM leaves. Over-exposure to the sun’s ultraviolet rays is a major environmental risk factor for skin cancer.

   • According to Pandey BR (2019)

     Excerpt This study focuses on the evaluation of phytochemical, antimicrobial, antioxidant properties of one of the ethnomedicinal plant Agave americana from Dhulikhel region of Nepal. Antioxidant activity was measured by DPPH assay é the cytotoxicity was evaluated using MCF-7 (human breast adenocarcinoma) cancer cell.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Misra AK (2018)

     Excerpt The anti-inflammatory effects were measured at regular intervals of time to see the percentage inhibition of paw edema & reduction of weight of granuloma with percentage protection to compare the effect of the extract with the control& standard. The plant contains flavonoids & genins which have been shown to have anti-edematous effects in the acute phase of inflammation.

   • According to Riaz S (2023)

     Excerpt With regard to inflammation in carrageenan-induced paw edema in rats, we aim to contrast the leaf extracts of Agave sisalana & Agave americana with standard drug Aliskiren. Agave species extract from Ae sisalana & A americana raised serum inflammatory indicators & promoted paw skin histology in groups that had been subjected to inflammation.

   • According to Lucila M (2022)

     Excerpt This review synthesizes the existing literature on the biologically active compounds of Agave species that are related in some way to inflammation, which will allow us to propose a line of research with this genus on the forefront to orient experimental designs for treating neuroinflammation & associated diseases. Reports show anti-inflammatory & antineuroinflammatory effects of these species, with flavonoids & saponins being mainly responsible.

   • According to Peana AT (1997)

     Excerpt Extracts of AA & genins isolated from them were evaluated for anti-inflammatory properties by testing their effects on carrageenin-induced edema. Lyophilized aqueous extracts obtained from Agave americana L (Agavaceae) collected in the north of Sardinia were characterized with regard to their steroidal sapogenin content.

   • According to El-Hawary SS (2020)

     Excerpt El-Hawary SS et al, Metabolomic Profiling of Five Agave Leaf Taxa via UHPLC/PDA/ESI-MS In relation to Their Anti-Inflammatory, Immunomodulatory & Ulceroprotective Activities.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.