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Alluim cepa (French onion) : medicinal properties in alcoholic extraction

Alluim cepa (French onion, Lonyon-frans, Oignon de France) — family Liliacées.

Scientific synonyms : Allium ascalonicum-Auct. non-L.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 18 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 51 scientific references for this species (full detail in the application).

Therapeutic indications in alcoholic extraction:

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

  1. Memory impairment in diabetic patients (red variety),

    Plant part used: Bulb.

    Scientific references (short excerpts)

    Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

    • According to Tamtaji Omid Reza (2017)

      Excerpt Conclusions: Our finding showed that oral administration of red Onion ethanolic extract improves learning & memory performances impaired by streptozotocin in diabetic rats. In addition, the induction of diabetes caused a significant impairment in memory consolidation compared with Health rats.

    • According to Gautam S (2015)

      Excerpt The present work was undertaken to investigate the effects and the molecular mechanism of the standardized ethanolic extract of Allium cepa (Onion) on the glucose transport for controlling diabetes mellitus. cepa extract also enhances the tyrosine phosphorylation of the insulin receptor-β, insulin receptor substrate-1, & the serine phosphorylation of Akt under both basal and insulin-stimulated conditions without affecting the total amount of these proteins.

    • According to AHMAD A (2025)

      Excerpt The results obtained showed that kaempferol identified with strong binding affinity with the selected diabetic target proteins and confirmed as the best bioactive compound with an overall interaction profile, antidiabetic property, & good oral drug likeness. Diabetes mellitus is a widespread metabolic disease affecting millions worldwide, while traditional medicine represents knowledge of healing practices inherited across generations and indigenous communities.

    • According to Galal EE (1965)

      Excerpt Galal EE et al; Antidiabetic activity of Egyptian Onion “Allium cepa” extract; Jl.

    • According to Compos KE (2003)

      Excerpt Compos KE et al; Hypoglycemic & antioxidant effect of Onion, Allium cepa: dietary Onion addition, antioxidant activity & hypoglycic effect on diabetic rats; Int Jl Food Sci Nutr.

  2. Hypercholesterolaemia, hyperlipidaemia, hypertriglyceridaemia: bulb fermented for 15 days: red-aggregatum variety

    Plant part used: Bulb.

    Scientific references (short excerpts)

    Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

    • According to Tamtaji Omid Reza (2017)

      Excerpt Conclusions: Our finding showed that oral administration of red Onion ethanolic extract improves learning & memory performances impaired by streptozotocin in diabetic rats. In addition, the induction of diabetes caused a significant impairment in memory consolidation compared with Health rats.

    • According to Gautam S (2015)

      Excerpt The present work was undertaken to investigate the effects and the molecular mechanism of the standardized ethanolic extract of Allium cepa (Onion) on the glucose transport for controlling diabetes mellitus. cepa extract also enhances the tyrosine phosphorylation of the insulin receptor-β, insulin receptor substrate-1, & the serine phosphorylation of Akt under both basal and insulin-stimulated conditions without affecting the total amount of these proteins.

    • According to AHMAD A (2025)

      Excerpt The results obtained showed that kaempferol identified with strong binding affinity with the selected diabetic target proteins and confirmed as the best bioactive compound with an overall interaction profile, antidiabetic property, & good oral drug likeness. Diabetes mellitus is a widespread metabolic disease affecting millions worldwide, while traditional medicine represents knowledge of healing practices inherited across generations and indigenous communities.

    • According to Galal EE (1965)

      Excerpt Galal EE et al; Antidiabetic activity of Egyptian Onion “Allium cepa” extract; Jl.

    • According to Compos KE (2003)

      Excerpt Compos KE et al; Hypoglycemic & antioxidant effect of Onion, Allium cepa: dietary Onion addition, antioxidant activity & hypoglycic effect on diabetic rats; Int Jl Food Sci Nutr.

  3. Infection: bacterial: Staphylococcus aureus, Salmonella Enteritidis,

    Plant part used: OTHERS.

    Scientific references (short excerpts)

    Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

    • According to Gautam S (2015)

      Excerpt The present work was undertaken to investigate the effects and the molecular mechanism of the standardized ethanolic extract of Allium cepa (Onion) on the glucose transport for controlling diabetes mellitus. cepa extract also enhances the tyrosine phosphorylation of the insulin receptor-β, insulin receptor substrate-1, & the serine phosphorylation of Akt under both basal and insulin-stimulated conditions without affecting the total amount of these proteins.

    • According to Tamtaji Omid Reza (2017)

      Excerpt Conclusions: Our finding showed that oral administration of red Onion ethanolic extract improves learning & memory performances impaired by streptozotocin in diabetic rats. Material & Methods: For induction of diabetes, streptozotocin (55 mg/kg) was injected intraperitoneally to male Wistar rats.

    • According to AHMAD A (2025)

      Excerpt The results obtained showed that kaempferol identified with strong binding affinity with the selected diabetic target proteins and confirmed as the best bioactive compound with an overall interaction profile, antidiabetic property, & good oral drug likeness. Diabetes mellitus is a widespread metabolic disease affecting millions worldwide, while traditional medicine represents knowledge of healing practices inherited across generations and indigenous communities.

    • According to Galal EE (1965)

      Excerpt Galal EE et al; Antidiabetic activity of Egyptian Onion “Allium cepa” extract; Jl.

    • According to Compos KE (2003)

      Excerpt Compos KE et al; Hypoglycemic & antioxidant effect of Onion, Allium cepa: dietary Onion addition, antioxidant activity & hypoglycic effect on diabetic rats; Int Jl Food Sci Nutr.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.

Evolution of this plant record

Under the CTA · public change history

Content

First public publication

New planttop 3 · ref count

By Emmanuel Nossin · ethnopharmacologist

Content

+9 indications · −9 indications · +2 synergies

Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Full bibliographic texts for new, corrected, or removed references expand below.

+9 indications−9 indications+2 synergies

By Emmanuel Nossin · ethnopharmacologist

Content

+2 indications · ~12 indications corrected · −1 indication

Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Full bibliographic texts for new, corrected, or removed references expand below.

+2 indications~12 indications corrected−1 indication

By Emmanuel Nossin · ethnopharmacologist