Aloysia citriodora (Vèvèn Sitwonnèl) : medicinal properties in alcoholic extraction

Aloysia citriodora (Vèvèn Sitwonnèl, Lemon verbena, Verveine citronnelle) — family Verbénacées.

Scientific synonyms : Aloysia Citriodora-Palau Lippia citriodora (P-)-Cav, Verbena trhylla-L’Her, Zappania citiodora-(P)-Lam..

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 55 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Neuropathic pain, sciatica

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Amin B (2018)

     Excerpt We examined the protective effects of ethanolic extract of Lippia citriodora on rats subjected to chronic constriction injury (CCI) of sciatic nerve & possible mechanisms of actions Materials & Methods: In this experimental study, the extract was administered 50, 100 & 200 mg/kg, Intraperitoneally (I.P) from the surgery time for 14 consecutive days. Conclusion: The results support the evidence that microglial activation & apoptosis are correlated with pain behaviors.

2. 2

   Bacterial infection: methicillin/penicillin-resistant Staphylococcus aureus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to AL-Maharik N (2024)

     Excerpt The EOs exhibited bactericidal properties, particularly against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), & showed highly effective fungicidal activity. The primary aim of this investigation was to determine the anticancer & antimicrobial properties of essential oils (EOs) extracted from the leaves of Aloysia citriodora Palau, which were procured from four separate locations in Palestine, in addition to analyzing their chemical composition.

   • According to JARADAT N (2021)

     Excerpt Interestingly, both EOs inhibited more potential activity against Methicillin-Resistant Staphylococcus aureus (MRSA) & Proteus vulgaris than Ciprofloxacin & Ampicillin antibiotics and also showed more potent antifungal activity against Candida albicans than Fluconazole. Aloysia citriodora Palau (AC) is commonly known as Lemon Verbena & has been utilized as a medicinal tea in folkloric medicine for the treatment of abdominal spasm, anxiety, & fever.

   • According to De las M recedes-OLIVA M, (2015)

     Excerpt Aloysia triphylla essential oil (EO) has antimicrobial activity on Staphylococcus aureus which is a pathogen responsible for severe infections & food contamination. aureus which main mechanism of action seems to be the cytoplasmic membrane disruption.

   • According to De las Mercedes Oliva M (n.d.)

     Excerpt The antimicrobial properties of Aloysia triphylla (L'Her.) Britton (cedrón) EO has been previously described. tropicalis which were resistant to fluconazol (150 mg/mL).

   • According to Etemad L (2016)

     Excerpt A wide range of biological activities are attributed to verbascoside including anti-inflammatory, antioxidant, anti-bacterial, anti-tumor, anti-fungal, photoprotective as well as chelating effects. Verbascoside (acteoside), a phenyl propanoid glycoside, comprises 0.5 to 3.5 % dry weight of Lippia citriodora leaves.

3. 3

   Hypoxia, dyspnoea, respiratory failure

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sanchez-Marzo N (2019)

     Excerpt Lippia citriodora has been traditionally used for respiratory, digestive, & muscular diseases, showing effects that are promoted by the antioxidant activity of its phytoconstituents.

   • According to Hosseinzadeh MH (2020)

     Excerpt In this study, protective effects of AC leaf extract against hypoxia-induced lethality in mice were evaluated by three experimental models of hypoxia, asphyctic, haemic & circulatory. Antihypoxic activity was especially pronounced in circulatory hypoxia where extract at 62.5 mg kg-1 prolonged the latency for death with respect to control group (p<0.01).

   • According to Ragone M (2007)

     Excerpt Aloysia citriodora is widely used for gastrointestinal disorders & as eupeptic in South America. The relaxation of 1mg/mL AEC was inhibited by hypoxia, but not that of 2mg/mL.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.