Alpinia zerumbet (Atoumo) : medicinal properties in alcoholic extraction

Alpinia zerumbet (Atoumo) — family Zingiberacées.

Scientific synonyms : Alpinia speciosa-(Wendl.)-K.Schum, Costus zerumbet-Pers, Catimbium speciosum-(W)-Hott, Renealmia nutans Andrews, Zerumbet speciosum-Wendl.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 60 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Adjuvant treatment of liver cancer, lung cancer, breast cancer, glioblastoma and leukaemia

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chuang CM (2011)

     Excerpt More importantly, the significant reduction in hepatic TG & total cholesterol (TC) implicated a crucial liver protective effect. In utilization of Alpinia zerumbet usually the angiocarps are discarded without further use.

   • According to ROMAN Jr Walter A (2017)

     Excerpt The hydroalcoholic extract inhibited cellular proliferation only at high concentrations, while the dichloromethane extract showed a moderate antiproliferative effect against leukemia & lung tumor cell lines. Pinostrobin showed potent activity against leukemia & breast tumor cell lines & moderate cytostatic effect against ovarian cell.

   • According to Satou T (2010)

     Excerpt In this report, GC-MS analysis was used to observe the tissue distribution of the multiple components of Alpinia zerumbet. zerumbet essential oil (AZEO) (alpha-pinene, p-cymene, 1, 8-cineole, a&limonene) was almost identical using either the injection or headspace injection method.

   • According to TESCHKE R (2018)

     Excerpt This diet includes shell ginger (Alpinia zerumbet (Pers.) B.L.

   • According to NARUSAKA M (2022)

     Excerpt Recently, PAC was isolated from leaves & pseudostems of the medicinal plant Alpinia zerumbet (Pers.) B.L. Proanthocyanidins (PACs) have various bioactivities, such as being anti-bacterial, anti-cancer, & anti-oxidant.

2. 2

   High blood pressure, oedema, fluid retention

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Nishidono Y (2019)

     Excerpt Nishidono Y et al, Anti-inflammatory kavalactones from Alpinia zerumbet, Fitoter, 140:104444, 2019-Abstract; Apinia zerumbet (Pers.) B.L. Moreover, the results of measurements of the anti-inflammatory activity revealed that the pericarps extract showed the strongest activity.

   • According to Yuandani (2023)

     Excerpt zerumbet (L.) Roscoe ex Sm., Alpinia galanga Linn., A. Among the bioactive metabolites, 6-, 8-,& 10-gingerols, 6-shogaol, & zerumbone from Zingiber species & cardamomin, 1′-acetoxychavicol acetate, yakuchinone, rutin, 1,8-cineole, & lectin from Alpinia species have demonstrated strong immunomodulating effects.

   • According to Humming W (2025)

     Excerpt The essential oil of Alpinia zerumbet (EOAz) has been used in the treatment of several medical conditions, including pain & inflammation, but scientific validation is scarce. The aim of this study was to investigate the antinociceptive & anti-inflammatory effects of EOAz in models of acute orofacial pain in rats & in inflammatory parameters in vitro.

   • According to HOU J (2024)

     Excerpt We reported here an interesting source of Alpinia zerumbet Polysaccharides (named AZPs) from the residues after extracting essential oil by steam distillation from AZ fructus. The results indicated that AZP-2 significantly decreased the production of NO & ROS in the inflammatory model established by lipopolysaccharide (LPS) stimulated RAW264.7, particularly at the concentration of 200 μg/mL.

   • According to HAQUE A (2017)

     Excerpt (family, Zingiberaceae) is a potent medicinal herb widely known as shampoo ginger & its rhizome is used in numerous ethnomedicinal applications including antipyretic, anti-inflammatory, antibacterial, anti-diarrheal, antidiabetics, carminative, & diuretic.

3. 3

   Hypercholesterolaemia, hypertriglyceridaemia, hyperlipidaemia

   Plant part used: SEED.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Xiao T (2020)

     Excerpt Alpinia zerumbet has been used as a flavor additive in food and a traditional medicine for centuries, especially in Guizhou Province, China, & it prolongs people’s lives with multiple beneficial effects. Moreover, 33 reports explain the antihypertensive & antiatherosclerotic effects of the plant by ameliorating inflammation & endothelial dysfunction, increasing vasodilation, improving hyperlipidemia, downgrading the glucose status, & working as an antioxidant.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.