Artemisia annua (Chinese mugwort) : medicinal properties in alcoholic extraction

Artemisia annua (Chinese mugwort, annual mugwort, Armoise de Chine, armoise annuelle) — family Astéracées.

Scientific synonyms : ---.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 27 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 69 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Adjuvant treatment for leukaemia, liver cancer and oral and laryngeal cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Choi FY (2021)

     Excerpt Conclusion: These results indicated that WEAA could reduce adipocyte differentiation & fat accumulation in in vitro & in vivo model systems, resulting in suppression of obesity & the occurrence of fatty liver due to a HFD.

   • According to CHOU EY (2022)

     Excerpt Next, to confirm protective effect of the WEAA in in vivo, mice were intragastrically administered with WEAA, extract of Silybum marianum or water once a day, & simultaneously provided with high-fat diet to induce fatty liver and hepatic steatosis. Our findings indicated that WEAA may be a potential intervention for preventing or treating hepatic lipid accumulation & liver damage.

   • According to KIM KE (2016)

     Excerpt Artemisia is a well-known source of the antimalarial drug artemisinin.

   • According to Efferth T (2011)

     Excerpt Cancer & Trypanosomal cells did not reveal cross-resistance among other compounds of Artemisia annua, namely the artemisinin-related artemisitene & arteanuine B as well as the unrelated compounds, scopoletin & 1,8-cineole. The isolation of artemisinin from Artemisia annua & its worldwide accepted application in malaria therapy is one of the showcase success stories of phytomedicine during the past decades.

   • According to Kim (2015)

     Excerpt In this study, extract from Artemisia annua in L. These results suggest that AAE induces cell cycle arrest at G1/S phase by Akt/mTOR pathway in HCT116 colon cancer cell.

2. 2

   Fatty liver disease

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Choi FY (2021)

     Excerpt Conclusion: These results indicated that WEAA could reduce adipocyte differentiation & fat accumulation in in vitro & in vivo model systems, resulting in suppression of obesity & the occurrence of fatty liver due to a HFD.

   • According to CHOU EY (2022)

     Excerpt Next, to confirm protective effect of the WEAA in in vivo, mice were intragastrically administered with WEAA, extract of Silybum marianum or water once a day, & simultaneously provided with high-fat diet to induce fatty liver and hepatic steatosis. Our findings indicated that WEAA may be a potential intervention for preventing or treating hepatic lipid accumulation & liver damage.

   • According to KIM KE (2016)

     Excerpt Artemisia is a well-known source of the antimalarial drug artemisinin.

   • According to Lee SK (2017)

     Excerpt We found that oral administration of Artemisia annua ethanol extract (AaE) or major components, artemisinin & arteannuin B, to ovariectomized (OVX) mice prevented bone loss, as verified by examining three-dimensional images & bone morphometric parameters derived from micoro-computed tomography analysis, as well as serum levels of bone turnover markers & proinflammatory cytokines. The administered doses were not toxic to the liver or kidney & showed promising effects that were comparable to those of 17β-estradiol treatment.

   • According to Zhu XX (2013)

     Excerpt Artemisia annua is a rich source of many bioactive substances, & in our recent work, a new sesquiterpene, (Z)-7-acetoxy-methyl-11-methyl-3-methylene-dodeca-1,6,10-triene (AMDT), was isolated and identified from hairy roots culture of A. AMDT showed moderate cytotoxic activities against the human tumor cell lines of HO8910 (ovary), 95-D (lung), QGY (liver) and HeLa (cervix) by MTT assay, whose IC (50) values were ranged within 52.44-73.3 microM.

3. 3

   Bacterial infection: Escherichia coli, Streptococcus faecalis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Candida albicans, Staphylococcus aureus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to OWUNA G (2013)

     Excerpt The minimum inhibitory concentration value of the ethanolic extract was 125 mg/ml for each of the test organisms: Escherichia coli, Streptococcus faecalis Pseudomonas aeruginosa, Klebsiella pneumoniae, Candida albicans & Staphylococcus aureus. studies were carried out on antimicrobial effects & phytoconstituents of Ethanolic extract of leaves of Artemisia annua.

   • According to Allemailem KS (2022)

     Excerpt pneumoniae), & Methicillin-Resistant Staphylococcus aureus (MRSA) using the agar well diffusion method & propidium iodide (PI)-stained microbial death under a confocal microscope. faecalis), Klebsiella pneumoniae (K.

   • According to KIM KE (2016)

     Excerpt Artemisia is a well-known source of the antimalarial drug artemisinin.

   • According to Mirbehbahani FS (2020)

     Excerpt Biological study of the A A containing wound dressing revealed no cytotoxicity, good proliferation & attachment of the seeded fibroblasts cells & acceptable antibacterial property against Staphylococcus aureus bacteria. The extract of this valuable plant provides anti-inflammatory, anti-bacterial & anti-microbial properties which can be considered as a promising medicinal component in therapeutic applications.

   • According to Golbarg H (2021)

     Excerpt Antibacterial activity of ethanolic & aqueous extracts of two medicinal plants including Oxalis corniculata (EtOc, AqOc) & Artemisia annua (EtAa, AqAa) as well as A. annua essential oil (EoAa) was investigated on multi-drug resistance (MDR) E.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.