Artemisia vulgaris (Labsent) : medicinal properties in alcoholic extraction

Artemisia vulgaris (Labsent, Absinthe) — family Asteracées.

Scientific synonyms : Absinthium spicatum (Wulfen ex Jacq.) Baumg., Artemisia affinis Hassk., A apetala hort.pest. ex Steud, A cannabifolia H. Lév., A opulenta-Pamp..

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 22 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 152 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Adjuvant treatment for cholangiocarcinoma and hepatocellular carcinoma

   Plant part used: Above-ground section.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Maki P (2023)

     Excerpt The objective was to investigate cytotoxic activity against hepatocellular carcinoma (HepG2), cholangiocarcinoma (KKU-M156) cells of Artemisia Vulgaris Extract, & its compound. It also demonstrated selective cytotoxic activity against liver cancer cells better than cholangiocarcinoma.

   • According to Sharmila K (2013)

     Excerpt The present study pertains to the use of Artemisia vulgaris as a source of anticancer agent. The methanolic extract of the leaves were tested in vitro against HepG2 (hepatocellular carcinoma) cells for their apoptotic properties in synergism with a standard chemotherapeutic drug, etoposide.

   • According to Vahdati-Mashhadian N (2009)

     Excerpt vulgaris against human Caucasian hepatocyte carcinoma (HepG-٢) & human Caucasian larynx carcinoma (Hep-٢) cell lines have been investigated. The cytotoxic effects of these concentrations against two human tumor cell lines, HepG-٢ & Hep-٢ were determined by quantitative MTT assay.

   • According to Gilani AH (2005)

     Excerpt The hepatoprotective effect was further verified by histopathology of the liver, which showed improved architecture, absence of parenchyma congestion, decreased cellular swelling & apoptotic cells, compared with the findings in the toxin group of animals. The effect of a crude extract of the aerial parts of Artemisia vulgaris (Av.

   • According to Ekiert H (2020)

     Excerpt Artemisia vulgaris L. Thus far, numerous authors have confirmed the beneficial properties of AV herb extracts, including their antioxidant, hepatoprotective, antispasmolytic, antinociceptive, estrogenic, cytotoxic, antibacterial, & antifungal effects.

2. 2

   Adjuvant treatment for liver cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sharmila K (2013)

     Excerpt The present study pertains to the use of Artemisia vulgaris as a source of anticancer agent. The methanolic extract of the leaves were tested in vitro against HepG2 (hepatocellular carcinoma) cells for their apoptotic properties in synergism with a standard chemotherapeutic drug, etoposide.

   • According to Maki P (2023)

     Excerpt The objective was to investigate cytotoxic activity against hepatocellular carcinoma (HepG2), cholangiocarcinoma (KKU-M156) cells of Artemisia Vulgaris Extract, & its compound. In regards to NCI criteria which consider that the value of IC50 of a good cytotoxic compound must be less than 4 µg/mL, therefore, it has the potential to be developed as an anti-cancer drug for liver cancer cells.

   • According to Vahdati-Mashhadian N (2009)

     Excerpt vulgaris against human Caucasian hepatocyte carcinoma (HepG-٢) & human Caucasian larynx carcinoma (Hep-٢) cell lines have been investigated. The cytotoxic effects of these concentrations against two human tumor cell lines, HepG-٢ & Hep-٢ were determined by quantitative MTT assay.

   • According to Al-Yassen A (2022)

     Excerpt In this study, the hepatoprotective effect of Iraqi AV against the liver toxic chemotherapy cisplatin were determined in mice. Artemisia vulgaris L.

   • According to Gilani AH (2005)

     Excerpt The hepatoprotective effect was further verified by histopathology of the liver, which showed improved architecture, absence of parenchyma congestion, decreased cellular swelling & apoptotic cells, compared with the findings in the toxin group of animals. The effect of a crude extract of the aerial parts of Artemisia vulgaris (Av.

3. 3

   Type II diabetes mellitus

   Plant part used: Above-ground section.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Neagu E (2023)

     Excerpt this work analyzed the antidiabetic & anti-inflammatory potential of Artemisia absinthium, Artemisia vulgaris & Trigonella foenum-graecum herbs, which have been studied less from this point of view. vulgaris; & genistin in T.FG The antidiabetic activity of the extracts was analyzed by testing their ability to inhibit α-amylase & α-glucosidase, & the anti-inflammatory activity was analyzed by testing their ability to inhibit hyaluronidase & lipoxygenase.

   • According to Hussain LG (2024)

     Excerpt That is why the aim of the current study was to determine the left ventricular remodeling potential of the methanolic extract of Artemisia vulgaris in a diabetic cardiomyopathy rat model. Artemisia vulgaris treatment significantly (p ≤ 0.05) reduced fasting blood glucose (108.5 ± 1.75 mg/dL), glycated hemoglobin (4.03 ± 0.12 %), serum glucose (116.66 ± 3.28 mg/dL), insulin (15.66 ± 0.66 ng/mL), total oxidant status (54.66 ± 3.22 µmol H2O2Equiv.L−1), Malondialdehyde (0.20 ± 0.01 mmol/L), total cholesterol (91.16 ± 3.35 mg/dL), triglycerides (130.66 ± 3.15 mg/dL), low-density lipids (36.57 ± 1.02 mg/dL), sodium (140 ± 3.21 mmol/L), calcium (10.44 ± 0.24 mmol/L), creatine kinase MB (1227.5 ± 17.89 IU/L), lactate dehydrogenase (1300 ± 34.64 IU/L), C-reactive protein (30 ± 0.57 pg/mL), tumor necrosis factor-α (58.66 ± 1.76 pg/mL), atrial natriuretic peptide (2.53 ± 0.04 pg/mL), B-type natriuretic peptide (10.66 ± 0.44 pg/mL), aspartate aminotransferase (86.5 ± 4.99 U/L), Alanine Transaminase (55.33 ± 2.90 U/L), urea (25.33 ± 1.15 mg/dL) & creatinine (0.64 ± 0.02 mg/dL) but significantly increased (p ≤ 0.05) total antioxidant capacity (1.73 ± 0.07 mmol Trolox Equil./L), high-density lipids (40 ± 1.59 mg/dL) & potassium (3.82 ± 0.04 mmol/L) levels.

   • According to Hussain M (2024)

     Excerpt It is in this context, the present review aims to provide a comprehensive account of the traditional uses, phytochemistry, documented biological properties & toxicity of all the species of Artemisia & offers useful insights for practitioners & researchers into underutilized species & their potential applications. Artemisia species have a rich history in traditional medicine worldwide, offering remedies for a wide range of ailments, such as malaria, jaundice, toothache, gastrointestinal problems, wounds, inflammatory diseases, diarrhoea, menstrual pains, skin disorders, headache, & intestinal parasites.

   • According to TAVARES WR (2025)

     Excerpt Metabolic syndrome, a cluster of metabolic disorders comprising dyslipidemia, insulin resistance, elevated blood pressure, & abdominal obesity, is a silent epidemic that may lead to outcomes such as cardiovascular disease, diabetes, & cancer. Regarding clinical trials concerning Artemisia, there are more studies aiming to see its effect on diabetes, but the studies about cancer are more advanced.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.