Azadirachta indica (Nim) : medicinal properties in alcoholic extraction

Azadirachta indica (Nim, Vèpèlè, Neem) — family Méliacées.

Scientific synonyms : Melia Azadirachta-L, M Indica- (A Juss) Brandis.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 37 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 191 scientific references for this species (full detail in the application).

Therapeutic indications in alcoholic extraction:

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

Vascular and haematological complications of diabetes: atherosclerosis, hypercholesterolaemia, abnormal blood count, etc.

Plant part used: Sheet.
Scientific references (short excerpts)

Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
- According to Itemobong E (2010)
  Excerpt The effects of ethanol extract of Azadirachta indica (Family: Meliaceae) leaves on Immunological & haematological parameters of alloxan-induced diabetic rats were investigated with a view to ascertaining its Involvement in the Immunological or inflammatory control of diabetic vascular complications. indica leaf extract appeared to be of clinical significance in the control of Atherosclerosis & other diabetic vascular complications in rats.
- According to Eshrat H (2002)
  Excerpt This study was carried out to investigate the effect of oral feeding of water extract of fresh leaves of Azadirachta indica in streptozotocin induced diabetes & its associated retinopathy in rats. indica at a dose of 250 mg/kg body weight for 16 weeks resulted in gradual but significant fall in blood glucose and improvement in serum total, LDL & HDL cholesterol & triacylglycerol which increased it1 diabetic rats.
- According to Saxena N (2018)
  Excerpt Antidiabetic activity using 100 mg/kg & 200 mg/kg of formulation was studied in streptozotocin induced diabetic albino Wistar rats. A polyherbal formulation was prepared containing herbs reported to have good antidiabetic activity & widely used traditionally in India by the folklore for the treatment of diabetes since ages.
- According to PARI L (2001)
  Excerpt Oral administration of Diamed (1.39 (0.25 g), 1.67 (0.30 g) or 1.94 (0.35 g) mL kg−1) for 30 days resulted in a significant reduction in blood glucose, glycosylated haemoglobin, & an increase in plasma insulin & total haemoglobin. We have investigated Diamed for its possible antihyperglycaemic action in rats with alloxan-induced experimental diabetes.
- According to Ramkumar S (n.d.)
  Excerpt Oral Starch Tolerance Test (OSTT) & 28-day efficacy study to check the effect of these orally administered inhibitors in diabetic rat models showed significant improvements in serum blood glucose & amylase levels as well as in other diabetes related serum parameters, namely, bilirubin, lipids, lactate dehydrogenase, alkaline phosphatase, & urea. Curcuma longa & Azadirachta indica are traditionally used in Indian cuisine & Ayurvedic medicine as nutraceuticals against diabetes.
Type II diabetes mellitus

Plant part used: Sheet.
Scientific references (short excerpts)

Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
- According to Itemobong E (2010)
  Excerpt The effects of ethanol extract of Azadirachta indica (Family: Meliaceae) leaves on Immunological & haematological parameters of alloxan-induced diabetic rats were investigated with a view to ascertaining its Involvement in the Immunological or inflammatory control of diabetic vascular complications. indica leaf extract appeared to be of clinical significance in the control of Atherosclerosis & other diabetic vascular complications in rats.
- According to PARI L (2001)
  Excerpt We have investigated Diamed for its possible antihyperglycaemic action in rats with alloxan-induced experimental diabetes. Oral administration of Diamed (1.39 (0.25 g), 1.67 (0.30 g) or 1.94 (0.35 g) mL kg−1) for 30 days resulted in a significant reduction in blood glucose, glycosylated haemoglobin, & an increase in plasma insulin & total haemoglobin.
- According to Ramkumar S (n.d.)
  Excerpt Curcuma longa & Azadirachta indica are traditionally used in Indian cuisine & Ayurvedic medicine as nutraceuticals against diabetes. Oral Starch Tolerance Test (OSTT) & 28-day efficacy study to check the effect of these orally administered inhibitors in diabetic rat models showed significant improvements in serum blood glucose & amylase levels as well as in other diabetes related serum parameters, namely, bilirubin, lipids, lactate dehydrogenase, alkaline phosphatase, & urea.
- According to Babu PS (2004)
  Excerpt Rats were rendered diabetic by streptozotocin (STZ) (45 mg kg (-1) body weight). Hyponidd is a herbomineral formulation composed of the extracts of ten medicinal plants (Momordica charantia, Melia Azadirachta, Pterocarpus marsupium, Tinospora cordifolia, Gymnema sylvestre, Eniscostema littorale, Emblica officinalis, Eugenia jambolana, Cassia auriculata & Curcuma longa).
- According to Rehman G (2023)
  Excerpt The biosynthesized AI-AgNPs and crude extracts of Azadirachta indica seeds were evaluated for anti-diabetic potentials using glucose adsorption assays, glucose uptake by yeast cells assays, & alpha-amylase inhibitory assays. Objective: In the present study, silver nanoparticles (AI-AgNPs) were biosynthesized through the green synthesis method using Azadirachta indica seed extract to evaluate their anti-diabetic potentials.
Alcoholic steatosis, cirrhosis, viral hepatitis (jaundice)

Plant part used: Sheet.
Scientific references (short excerpts)

Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
- According to Sariana I (2021)
  Excerpt This study aimed to investigate the effect of the ethanol extract of Azadirachta Indica leaves on the concentration of aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, & creatinine in male rats. The results showed that the ethanolic extract of AI leaves did not affect the concentration of AST, ALT, & creatinine, The ethanol leaves reduced extract on the urea concentration, no abnormal changes were observed in the liver & kidney organs.
- According to Sitasiwi AJ (2018)
  Excerpt The hepatic weights and HSI values of the control group showed nonsignificant differences (p>0.05) with the P1 and P2 treatment groups but showed a significant difference (p<0.05) with the P3 treatment group. The mice were anesthetized with chloroform at the end of treatment, continued by dissecting & isolating liver isolation.
- According to Seriana I (2021)
  Excerpt Neem (Azadirachta indica is one of the tropical plants found in Indonesia that has been used to prevent & treat various diseases. The results showed that the ethanolic extract of neem leaves did not affect the concentration of AST, ALT, & creatinine, The ethanol leaves reduced extract on the urea concentration, no abnormal changes were observed in the liver & kidney organs.
- According to Panda S (2000)
  Excerpt In this investigation we attempted to find out the hitherto unstudied adverse effects of neem (Azadirachta indica) leaf extract on the thyroid function of male mice. A concomitant increase in hepatic lipid peroxidation (LPO) & a decrease in glucose-6-phosphatase (G-6-Pase) activity in the higher dosed group also indicated the adverse effect of neem extract despite an enhancement in the activities of two defensive enzymes, superoxide dismutase (SOD) & catalase (CAT).
- According to Batra N (2022)
  Excerpt This review focuses on extracts & phytochemicals derived from the Neem tree (Latin name; Azadirachta indica), commonly used throughout Southeast Asia for the prevention & treatment of a wide array of diseases including cancer. To date, there are more than 130 biologically active compounds that have been isolated from the Neem tree including azadirachtin, nimbolinin, nimbin, nimbidin, nimbidol, which have demonstrated a wide range of biological activities including anti-microbial, anti-fertility, anti-inflammatory, anti-arthritic, hepatoprotective, anti-diabetic, anti-ulcer, & anti-cancer effects.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.

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Evolution of this plant record

Under the CTA · public change history

Content30 Jun 2026, 07:35 pm

+1 indication · +1 synergy · +34 references · −24 references

Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Full bibliographic texts for new, corrected, or removed references expand below.

+1 indication+1 synergy+34 references−24 references

+34 references — show text

Gbotolorun SCV et al, Antifertility potential of Neem flower extract on adult female Sprague-Dawley rats. African 545 Health Sci, 8 :168-173, 2008-Abstract: The search for a relatively cheap, widely available, widely accepted and effective contraceptive of plant origin; that is equally non-invasive in administration, non-hormonal in action, non-toxic and that is relatively long-acting, generated our interest in this study (in order to meet the increasing need for population control). The aim of this study was to determine the effects of alcoholic extract of Neem flowers on the estrous cycle…

Added

Baswa M et al, Antibacterial activity of Karanj (Pongamia pinnata) & Neem (Azadirachta indica) seed oil: A preliminary report. Microbiol. 2001; 105:183–9.- Abstract : The antibacterial activity of Karanj (P. pinnata) & neem (A. indica) seed oil in vitro against Pseudomonas aeruginosa Bacillus circulans bacillus circulans Vibrio cholerae vibrio choleraes, Escherichia coli escherichia coli Shigella dysenteriae shigella dysenteriae, Shigella flexneri shigella flexneri, Shigella boydii, Staphylococcus staphylococcus , Salmonella typhi salmonella typhi& Salmonella paratyphi salmonella paratyphi …

Added

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;Unknown

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;

Added

Mackinnon S et al, Antimalarial activity of tropical Meliaceae extracts & gedunin derivatives. Jl Nat Prod 60:336–41, 1997-Abstract: Extracts of 22 species of Meliaceae were examined for antimalarial activity using in vitro tests with two clones of Plasmodium falciparum, one sensitive to chloroquine (W2) & one chloroquine-resistant (D6). Twelve extracts were found to have activity, including extracts of Cedrela odorata wood & Azadirachta indica leaves, which contained the limonoid gedunin. These extracts were more effective against the W2 clone than the D6 clone, suggesting there is no cros…

Added

Gbotolorun SCV et al, Antifertility potential of Neem flower extract on adult female Sprague-Dawley rats. African 545 Health Sci, 8 :168-173, 2008-Abstract: The search for a relatively cheap, widely available, widely accepted & effective contraceptive of plant origin; that is equally non-invasive in administration, non-hormonal in action, non-toxic and that is relatively long-acting, generated our interest in this study (in order to meet the increasing need for population control). The aim of this study was to determine the effects of alcoholic extract of Neem flowers on the estrous cycle, …

Added

Mukherjee N et al, Ethanolic extract of Azadirachta indica (A. Juss.) causing apoptosis by ROS upregulation in Dirofilaria immitis microfilariae, Res In Vet Sci, 97(2) :309-17, 2014.-Abstract : Dirofilaria immitis is the causative agent of cardiopulmonary dirofilariasis in the Canine family. The aim of the study was to evaluate the efficacy of the ethanolic extract of Azadirachta indica leaves (EEA) against the microfilariae (mf) of D. immitis in vitro. EEA was evaluated for different compound classes through HPTLC. Relative motility, mortality& morphological alterations were observed in th…

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Manikandan P et al, Evaluation of Azadirachta indica leaf fractions for in vitro antioxidant potential & in vivo modulation of biomarkers of chemoprevention in the hamster buccal pouch carcinogenesis model. Semantic Scholars, 2008-Abstract: We evaluated the chemopreventive potential of Azadirachta indica (neem) leaf fractions based on in vitro antioxidant assays, & in vivo inhibitory effects on 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch (HBP) carcinogenesis. In addition we also identified the major constituents in neem leaf fractions by HPLC. Analysis of the free rad…

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OHOUKO OFJ et al, Diabetes mellitus in ECOWAS: an overview of the safety & efficacy of medicinal plants used in traditional medicine practices, Trop Med Health, 54(1):56. 2026-Abstract: The rich biodiversity of West Africa supports a vast repository of medicinal plants, with traditional medicine playing a central role in managing diseases such as diabetes. Despite their widespread use, the safety a&efficacy of these herbal treatments have not been scientifically explored. This study aims to analyze the traditional uses of antidiabetic plants in Economic Community of West African States coun…

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Mukherjee N et al, Antifilarial effects of polyphenol rich ethanolic extract from the leaves of Azadirachta indica through molecular & biochemical approaches describing reactive oxygen species (ROS) mediated apoptosis of Setaria cervi, Experiment Parasitol, 136 :41-58, 2014.-Abstract: In this work we have evaluated the Antifilarial efficacy of an optimized polyphenol rich ethanolic extract of Azadirachta indica leaves (EEA). A. indica A. Juss has been widely used in the traditional Indian medicinal system ‘Ayurveda’ for the treatment of a variety of ailments. A thorough investigation toward…

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Cheenickal M et al, PHYTOCHEMICAL SCREENING & THE ANTIMICROBIAL ACTIVITY OF THE LEAVES OF AZADIRACHTA INDICA A. JUSS, Inter Jl of Sci & Engineering Res, 8: 5, 2017.-ABSTRACT: The present study includes the phytochemical detection & antimicrobial activity of the leaves of Azadirachta indica. Phytochemical screening of the leaf extract of leaves both fresh & shade dried indicated the presence of flavonoids, terpenoids, tannins, alkaloids, steroids & glycosides. The antibacterial activity of methanol, ethanol & aqueous extracts of leaves of A. indica was evaluated against the human pathogenic …

Added

Sitasiwi et al, The Swiss Webster mice testes structure after exposed to ethanolic neem (Azadirachta indica) leaf extract, JL Phys: Conf. Ser. 1217 012137, 2019-Abstract: Neem has been known as an anti-fertility effect, both in male & female mammals. This research was performed to find out the effect of ethanolic leaf extract of A. indica on the testes structure that indicated by testicular weight, diameter, & thickness of germinal epithelium of seminiferous tubules. Twenty Swiss Webster male mice were used, & they were divided into two groups (K & P) of ten in replicates. The mice in the K…

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Siva-lingam AM et al, Phytochemicals analysis & GC-MS analysis of identification & characterization of bioactive compounds presents in methanolic leaf extract Azadirachta indica, Inter Jl of Pharmaceut Sci & Drug Res, 1(1):39-50, 2021-Abstract: Azadirachta indica phytochemicals growth & hostile to bacterial properties. In the specific research, the mixture ability of five mixes that are available in the AI with all the eleven proteins through in the silico techniques was done. Plant extricates ensure against harmful compound instigated injury by expanding the body's degrees of cancer preven…

Added

Khan IN et al, Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. & Anacardium occidentale L. Jl Basic Clin Pharm; 2(3): 125-7, 2011-Abstract: Herbal preparations have been used since Ancient times for the treatment of several diseases. The Aim of this study was to investigate whether herbal preparations possess thrombolytic activity or not. An in vitro thrombolytic model was used to check the clot lysis effect of four aqueous herbal extracts viz. Ocimum sanctum, Curcuma longa,Azadirachta indica, A. occidentale along with Streptokinase as a positive control…

Added

Cheenickal M et al, PHYTOCHEMICAL SCREENING & THE ANTIMICROBIAL ACTIVITY OF THE LEAVES OF AZADIRACHTA INDICA A. JUSS, Inter Jl of Sci & Engineering Res, 8: 5, 2017.-ABSTRACT: The present study includes the phytochemical detection & antimicrobial activity of the leaves of Azadirachta indica. Phytochemical screening of the leaf extract of leaves both fresh & shade dried indicated the presence of flavonoids, terpenoids, tannins, alkaloids, steroids a& glycosides. The antibacterial activity of methanol, ethanol & aqueous extracts of leaves of A. indica was evaluated against the human pathogenic…

Added

Sitasiwi et al, The Swiss Webster mice testes structure after exposed to ethanolic neem (Azadirachta indica) leaf extract, J.l Phys: Conf. Ser. 1217 012137, 2019-Abstract: Neem has been known as an anti-fertility effect, both in male & female mammals. This research was performed to find out the effect of ethanolic leaf extract of A. indica on the testes structure that indicated by testicular weight, diameter, & thickness of germinal epithelium of seminiferous tubules. Twenty Swiss Webster male mice were used, & they were divided into two groups (K & P) of ten in replicates. The mice in the …

Added

Manikandan P et al, Combinatorial Chemopreventive effect of Azadirachta indica & Ocimum sanctum on oxidant-antioxidant status, cell proliferation, apoptosis & angiogenesis in à rat for stomach Carcinogenesis, model. Singapore Med Jl. 2008, 49(10):814-22-Abstract: We investigated the combinatorial chemopreventive efficacy of Azadirachta indica (AI) & Ocimum sanctum (OS) against N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis, based on changes in oxidant-antioxidant status, cell proliferation, apoptosis & angiogenesis. Methods: Male Wistar rats were assigned to four…

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Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;Unknown

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;

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Namadi S et al, Physico-Mechanical Properties of Fuel Briquette Made from Raw a& Torrefied Neem & Tropical Almond Tree Branches Using Different Organic Binders. Asian Jl. Res. Rev. Phys. 9:20–35. doi: 10.9734/ajr2p/2025/v9i2187. 2025-Abstract: This study examines the physico-mechanical properties of briquettes produced from Neem (Azadirachta indica) & Tropical Almond (Terminalia catappa) branch residues, processed in both raw & torrefied forms, using cassava starch flour & African locust bean (Parkia Biglobosa) pulp as binding agents. A total of 36 samples were produced with varying biomas…

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Vasenwala S et al, A study on antioxidant & apoptotic effect of Azadirachta Indica (neem) in cases of cervical cancer, Arch of Gynecol & Obstetrics, 10, 2012-Abstract:Methods: Results: Conclusion: NeeVasenwala S · 2012

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Plants: Azadirachta indica, Emblica officinalis, Eucalyptus sp., Ficus religiosa, Lantana camara L., Lawsonia inermis, Nyctanthes arbor-tristis, Ocimum sanctum, Punica granatum, Syzygium cumini, Terminalia arjuna, Beta vulgaris, Camelia sinensis, Hemidesmus indicus, Holarrhena antidysenterica, Morus Alba, Saussurea lappa, Syzygium aromaticum,

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BREVET: US8067043B2: Herbal composition for treatment of hyperlipidemia & the inhibition of myocardial infarction: Abstract: A pharmaceutical or medicinal herbal composition and method of making the composition comprised of a mixture of the following herbal ingredients: Glycine max, Plumbago zeylanica, Terminalia Arjuna, Trigonella-foenum-graecum, Coleus forskohlii, Commiphora mukul, Camellia sinensis & Azadirachta indica.

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Vasenwala S et al, A study on antioxidant & apoptotic effect of Azadirachta Indica (neem) in cases of cervical cancer, Arch of Gynecol & Obstetrics, 10, 2012-Abstract: To study the anti-oxidant properties of neem (Azadirachta indica) in inducing apoptosis of cervical cancer cells & estimation of caspase activity & TNF-α & IFN-γ levels in monocytes of cervical cancer patients & controls. Methods: Monocytes were cultured from blood samples of 65 study cases & 30 controls for the estimation of caspase 3, 8 & 9 with specific inhibitors & TNF-α & IFN-γ levels in culture supernatant of monocytes.…

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Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;Unknown

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;

Added

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;Unknown

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;

Added

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.Unknown

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.

Added

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;Unknown

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;

Added

PERERA WPRT et al, Antiviral Potential of Selected Medicinal Herbs & Their Isolated Natural Products, Biomed Res Int, 7572406, 2021-Abstract: Viruses are responsible for a variety of human pathogenesis. Owing to the enhancement of the world population, global travel, & rapid urbanization, & infectious outbreaks, a critical threat has been generated to public health, as preventive vaccines & antiviral therapy are not available. Herbal medicines & refined natural products have resources for the development of novel antiviral drugs. These natural agents have shed light on preventive vaccine de…

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Siva-lingam AM et al, Phytochemical Analysis & Anticancer Activity of Azadirachta Indica Ethanolic Extract against A549 Human Lung Cancer Cell Line, Jl of Biomed Res, 2(4):280-5, 2021-Abstract: Azadirachta indica phytochemicals are found to have against malignant growth & hostile to bacterial properties. In the specific examination, the coupling proficiency of fi ve mixes that are available in the Azadirachta indica with all the eleven proteins through in silico techniques was completed. Plant removes ensure against harmful compound instigated injury by expanding the body's degrees of cell…

Added

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;Unknown

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;

Added

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;Unknown

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;

Added

Baswa M et al, Antibacterial activity of Karanj (Pongamia pinnata) & Neem (Azadirachta indica) seed oil: A preliminary report. Microbiol. 2001; 105:183–9.- Abstract : The antibacterial activity of Karanj (P. pinnata) & neem (A. indica) seed oil in vitro against Pseudomonas aeruginosa Bacillus circulans bacillus circulans Vibrio cholerae vibrio cholerae, Escherichia coli Escherichia coli Shigella dysenteriae shigella dysenteriae, Shigella flexneri shigella flexneri, Shigella boydii, Staphylococcus staphylococcus , Salmonella typhi salmonella typhi& Salmonella paratyphi salmonella paratyphi w…

Added

Mackinnon S et al, Antimalarial activity of tropical Meliaceae extracts & gedunin derivatives. Jl Nat Prod 60:336–41, 1997-Abstract: Extracts of 22 species of Meliaceae were examined for antimalarial activity using in vitro tests with two clones of Plasmodium falciparum, one sensitive to chloroquine (W2) & one chloroquine-resistant (D6). Twelve extracts were found to have activity, including extracts of Cedrela odorata wood & Azadirachta indica leavesbetter activity than chloroquine against the W2 clone. This active principle could be used to standardize a popular crude drug based on tradit…

Added

Khan IN et al, Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. & Anacardium occidentale L. Jl Basic Clin Pharm; 2(3): 125-7, 2011.-Abstract: Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed xin blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the treatment of several diseases. Th…

Added

Hussain S et al, Synergistic Antibacterial Screening of Cymbopogon citratus & Azadirachta indica : Phytochemical Profiling & Antioxidant & Hemolytic Activities, ACS Omega, 8:19, 2023-Abstract: Current studies were performed to investigate the phytochemistry, synergistic antibacterial, antioxidant, & hemolytic activities of ethanolic & aqueous extracts of Azadirachta indica (EA & WA) & Cymbopogon citratus (EC & WC) leaves. Fourier transform infrared data verified the existence of alcoholic, carboxylic, aldehydic, phenyl, & bromo moieties in plant leaves. The ethanolic extracts (EA & EC) were…

Added

Removed

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;Unknown

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;

Removed

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;Unknown

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;

Removed

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;Unknown

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;

Removed

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;Unknown

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;

Removed

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;Unknown

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;

Removed

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;Unknown

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;

Removed

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;Unknown

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;

Removed

Cheenickal M et al, PHYTOCHEMICAL SCREENING & THE ANTIMICROBIAL ACTIVITY OF THE LEAVES OF AZADIRACHTA INDICA A. JUSS, Inter Jl of Sci & Engineering Res, 8: 5, 2017.-ABSTRACT: The present study includes the phytochemical detection & antimicrobial activity of the leaves of Azadirachta indica. Phytochemical screening of the leaf extract of leaves both fresh & shade dried indicated the presence of flavonoids, terpenoids, tannins, alkaloids, steroids a& glycosides. The antibacterial activity of methanol, ethanol & aqueous extracts of leaves of A. indica was evaluated against the human pathogenic…

Removed

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.Unknown

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.

Removed

Mackinnon S et al, Antimalarial activity of tropical Meliaceae extracts & gedunin derivatives. Jl Nat Prod 60:336–41, 1997-Abstract: Extracts of 22 species of Meliaceae were examined for antimalarial activity using in vitro tests with two clones of Plasmodium falciparum, one sensitive to chloroquine (W2) & one chloroquine-resistant (D6). Twelve extracts were found to have activity, including extracts of Cedrela odorata wood & Azadirachta indica leavesbetter activity than chloroquine against the W2 clone. This active principle could be used to standardize a popular crude drug based on tradit…

Removed

Khan IN et al, Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. & Anacardium occidentale L. Jl Basic Clin Pharm; 2(3): 125-7, 2011-Abstract: Herbal preparations have been used since Ancient times for the treatment of several diseases. The Aim of this study was to investigate whether herbal preparations possess thrombolytic activity or not. An in vitro thrombolytic model was used to check the clot lysis effect of four aqueous herbal extracts viz. Ocimum sanctum, Curcuma longa, AAzadirachta indica, A. occidentale along with Streptokinase as a positive contr…

Removed

By Emmanuel Nossin · ethnopharmacologist

Content26 Jun 2026, 03:32 pm

+2 indications · −2 indications · +3 synergies · +18 references · −18 references

Counts and domains only: indication labels and synergy names are not listed here (open the in-app plant file). Full bibliographic texts for new, corrected, or removed references expand below.

+2 indications−2 indications+3 synergies+18 references−18 references

+18 references — show text

Added

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;Unknown

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;

Added

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;Unknown

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;

Added

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;Unknown

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;

Added

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;Unknown

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;

Added

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;Unknown

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;

Added

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;Unknown

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;

Added

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;Unknown

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;

Added

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.Unknown

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.

Added

Khan IN et al, Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. & Anacardium occidentale L. Jl Basic Clin Pharm; 2(3): 125-7, 2011-Abstract: Herbal preparations have been used since Ancient times for the treatment of several diseases. The Aim of this study was to investigate whether herbal preparations possess thrombolytic activity or not. An in vitro thrombolytic model was used to check the clot lysis effect of four aqueous herbal extracts viz. Ocimum sanctum, Curcuma longa, AAzadirachta indica, A. occidentale along with Streptokinase as a positive contr…

Added

Removed

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;Unknown

Coleus forskohlii root extract in an amount of 10-15% by weight of the composition, wherein the Coleus forskohlii root extract contains greater than 2.5% forskolin;

Removed

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;Unknown

Terminalia arjuna bark extract in an amount of 10-15% by weight of the composition, wherein the Terminalia arjuna bark extract contains about 25% tannins and greater than 1% arjunic acid;

Removed

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;Unknown

Trigonella-foenum graecum seed extract in an amount of 10-15% by weight of the composition, wherein the Trigonella-foenum graecum seed extract contains about 10% saponins;

Removed

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;Unknown

Plumbago zeylanica root extract in an amount of 10-15% by weight of the composition, wherein the Plumbago zeylanica root extract contains about 0.08-0.15% alkaloids;

Removed

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;Unknown

Glycine max seed extract in an amount of 10-15% by weight of the composition, wherein the Glycine max seed extract contains about 40% isoflavones;

Removed

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;Unknown

Commiphora mukul resin extract in an amount of 10-15% by weight of the composition, wherein the Commiphora mukul resin extract contains about 2.5-10% guggul sterones;

Removed

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;Unknown

Camellia sinensis leaf extract in an amount of 10-15% by weight of the composition, wherein the Camellia sinensis leaf extract contains greater than 45% polyphenols;

Removed

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.Unknown

Azadirachta indica bark extract in an amount of 5-7.5% by weight of the composition, wherein the Azadirachta indica bark extract contains about 2.5% bitters.

Removed

Khan IN et al, Thrombolytic potential of Ocimum sanctum L., Curcuma longa L., Azadirachta indica L. & Anacardium occidentale L. Jl Basic Clin Pharm; 2(3): 125-7, 2011-Abstract: Herbal preparations have been used since Ancient times for the treatment of several diseases. The Aim of this study was to investigate whether herbal preparations possess thrombolytic activity or not. An in vitro thrombolytic model was used to check the clot lysis effect of four aqueous herbal extracts viz. Ocimum sanctum, Curcuma longa, AAzadirachta indica, A. occidentale along with Streptokinase as a positive contr…

Removed

By Emmanuel Nossin · ethnopharmacologist

Content26 Jun 2026, 03:32 pm

First public publication

New planttop 3 · ref count

By Emmanuel Nossin · ethnopharmacologist

Azadirachta indica (Nim) : medicinal properties in alcoholic extraction

Vascular and haematological complications of diabetes: atherosclerosis, hypercholesterolaemia, abnormal blood count, etc.

Type II diabetes mellitus

Alcoholic steatosis, cirrhosis, viral hepatitis (jaundice)

Evolution of this plant record

+1 indication · +1 synergy · +34 references · −24 references

+2 indications · −2 indications · +3 synergies · +18 references · −18 references

First public publication