Borago officinalis (Bourach) : medicinal properties in alcoholic extraction

Borago officinalis (Bourach, Borage, Bourrache) — family Boraginacées.

Scientific synonyms : Borago hortensis-L.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 62 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Hepatitis, cirrhosis, fatty liver

   Plant part used: Aerial_parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to HAMED AN (2015)

     Excerpt The present study aims to investigate the hepatoprotective effect of Borago officinalis aerial ethanolic extract (BAEE) against CCl4-induced liver damage in comparison to silymarin, a Classical antioxidant liver medicine. The hepatoprotective potential of BAEE in rats was evaluated following oral administration of CCl4, which enhanced hepatic lipid peroxidation & notably depleted reduced glutathione.

   • According to Senamayake SPIN (1999)

     Excerpt Senamayake SPIN et al, Enzyme assisted acidolysis of borage (Borago officinalis L.) and Evening Primrose (Oenothera biennis L.) oils: Incorporation of Omega 3-Polyunsaturated Fatty Acids, J.

   • According to Author (2001)

     Excerpt Aghofack-Nguemezi J., Onthogeny of short & medium chain fatty acid content in Borago officinalis L.

   • According to De Haro A (2002)

     Excerpt De Haro A et al, Variability in the content of gamma-linnaoic acid & other fatty acids of the seed oïl of Germoplasm of wild & cultivated borage (Borago officinalis L.), J of Herbs, Spices & Med Plants, 2002, 9; 297-304.

   • According to Ramandi NF (2011)

     Excerpt Ramandi NF et al, Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L.

2. 2

   Fungal infection: Candida, Aspergillus niger

   Plant part used: Sheet. Mentioned synergistic association: Camélia sinensis.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to EIDI Samaneh (2014)

     Excerpt The current study aimed to evaluate & compare the antifungal activity of hydroalcoholic extracts of Borage officinalis & Camellia sinensis (Green tea) against different Candida & Aspergillus strains. The combined use of green tea or B officinalis extracts & antifungals could be also useful in fighting emerging drug-resistant problem among fungal pathogens.

   • According to Vafaei Mozhan (n.d.)

     Excerpt Borago officinalis is an annual herb naturalized throughout the Mediterranean region, as well as Asia Minor, Europe, North Africa, & South America. officinalis was tested against 3 Gram positive: Bacillus Cereus, Staphylococcus aureus & Staphylococcus epidermidis & 5 Gram negative: Salmonella typhi, Klebsiella pneumonia, Escherichia coli, Pseudomonas aeruginosa, & Proteus mirabilis ATCC bacterial species by disc diffusion methods at various concentrations from 600 mg 􀓏ml to 50 mg 􀓏ml.

   • According to Barbakatze (2023)

     Excerpt Biopolymers from SC & AI roots showed antifungal activities against all six fungi, in contrast to the antibacterial activity, while biopolymers from CO stems & SA roots had activities against four fungi and one fungus, respectively. gr & iflorum (SG), Anchusa italica (AI), Cynoglosum officinale (CO), & Borago officinalis (BO) collected in various parts of Georgia.

3. 3

   Bacterial infection: Staphylococcus aureus, Staphylococcus epidermidis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vafaei Mozhan (n.d.)

     Excerpt officinalis was tested against 3 Gram positive: Bacillus Cereus, Staphylococcus aureus & Staphylococcus epidermidis & 5 Gram negative: Salmonella typhi, Klebsiella pneumonia, Escherichia coli, Pseudomonas aeruginosa, & Proteus mirabilis ATCC bacterial species by disc diffusion methods at various concentrations from 600 mg 􀓏ml to 50 mg 􀓏ml. Conclusion: This extract can be used as antibacterial substance against some bacterial species such as S aureus & S epidermidis.

   • According to EIDI Samaneh (2014)

     Excerpt The current study aimed to evaluate & compare the antifungal activity of hydroalcoholic extracts of Borage officinalis & Camellia sinensis (Green tea) against different Candida & Aspergillus strains. The B officinalis extract showed the highest antifungal activity against A.

   • According to Barbakatze (2023)

     Excerpt Biopolymers from SC & AI roots showed antifungal activities against all six fungi, in contrast to the antibacterial activity, while biopolymers from CO stems & SA roots had activities against four fungi and one fungus, respectively. gr & iflorum (SG), Anchusa italica (AI), Cynoglosum officinale (CO), & Borago officinalis (BO) collected in various parts of Georgia.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.