Caesalpinia decapetala (Kanikrôk) : medicinal properties in alcoholic extraction

Caesalpinia decapetala (Kanikrôk, zarèt-bèf, Stop, ox, Arrête-bœuf, Para, buey) — family Caesalpiniacées.

Scientific synonyms : Biancaea decapetala (Roth) O.Deg., B scandens Tod., B sepiaria (Roxb.) Tod., Caesalpinia benguetensis Elmer, C ferox Hassk., Caesalpinia sepiaria Roxb., Mezoneuron benguetense (Elmer) Elmer, Reichardia decapetala Roth.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 17 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for gastric carcinoma

   Plant part used: stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zanin, J.L.B (2012)

     Excerpt It has been reported in the literature that these species exhibit a wide range of pharmacological properties, including antiulcer, anticancer, antidiabetic, anti-inflammatory, antimicrobial, & antirheumatic activities that have proven to be efficacious in ethnomedicinal practices. The genus Caesalpinia (Caesalpiniaceae) has more than 500 species, many of which have not yet been investigated for potential pharmacological activity.

   • According to Zhang Q (2008)

     Excerpt The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston & investigates the bioactivities of the isolated compounds. Emodin (6), baicalein (9), & apigenin (12) displayed antitumor activities against the MGC-803 cell line, while quercetin (2), rutin (5), baicalein (9), & epicatechin (13) showed stronger DPPH scavenging activities compared with ascorbic acid.

   • According to Gallego MG (2017)

     Excerpt The antioxidant effects of an extract from Caesalpinia decapetala (Fabaceae) were assessed by storage of model food oil-in-water emulsions with analysis of primary & secondary oxidation products. Caesalpinia decapetala (Roth) Alston (Fabaceae) (CD) is used in folk medicine to prevent colds & treat bronchitis.

2. 2

   Viremia: Influenza virus: Type A & B, oseltamivir-resistant H1N1 (H274Y), in lung cancer and generalised histiocytic lymphoma

   Plant part used: aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zhang Q (2008)

     Excerpt The current study targets the chemical constituents of Caesalpinia decapetala (Roth) Alston & investigates the bioactivities of the isolated compounds. Emodin (6), baicalein (9), & apigenin (12) displayed antitumor activities against the MGC-803 cell line, while quercetin (2), rutin (5), baicalein (9), & epicatechin (13) showed stronger DPPH scavenging activities compared with ascorbic acid.

   • According to Zanin, J.L.B (2012)

     Excerpt It has been reported in the literature that these species exhibit a wide range of pharmacological properties, including antiulcer, anticancer, antidiabetic, anti-inflammatory, antimicrobial, & antirheumatic activities that have proven to be efficacious in ethnomedicinal practices. The genus Caesalpinia (Caesalpiniaceae) has more than 500 species, many of which have not yet been investigated for potential pharmacological activity.

   • According to Gallego MG (2017)

     Excerpt The antioxidant effects of an extract from Caesalpinia decapetala (Fabaceae) were assessed by storage of model food oil-in-water emulsions with analysis of primary & secondary oxidation products. Caesalpinia decapetala (Roth) Alston (Fabaceae) (CD) is used in folk medicine to prevent colds & treat bronchitis.

   • According to ZHANG L (2020)

     Excerpt In this study, we identified the ethanol extract of Caesalpinia decapetala (Roth) Alston (EEC) as an inhibitor against the replication of a panel of influenza A & B viruses both on human pulmonary epithelial A549 & human monocytic U937 cells. Because of the diversity of influenza virus strains & drug resistance to the current direct antiviral agents, there have been no effective drugs as yet to cure all patients infected by influenza viruses.

3. 3

   Oxidative stress

   Plant part used: Trunk bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pawar CR (2010)

     Excerpt The antioxidant activities of the methanol extracts from the wood & pericarp of Caesalpinia decapetala (Roth) Alston (Caesalpiniaceae) were assessed in efforts to validate the herb. The antioxidant activity & phenolic content of the pericarp as determined by the DPPH, superoxide radical, nitric oxide radical, total phenols, ,0the flavonoids, & total flavonols were higher than that of the wood.

   • According to Gallego MG (2017)

     Excerpt The antioxidant effects of an extract from Caesalpinia decapetala (Fabaceae) were assessed by storage of model food oil-in-water emulsions with analysis of primary & secondary oxidation products. Caesalpinia decapetala (Roth) Alston (Fabaceae) (CD) is used in folk medicine to prevent colds & treat bronchitis.

   • According to Pawar CR (2010)

     Excerpt Caesalpinia decapetala is a wild plant found in the Sub-Himalayan tract & planted in hedges throughout in India. The bark of Caesalpinia decapetala is a rich source of tannins.

   • According to Gallego MG (2016)

     Excerpt The extracts (0.5% [w/w]) from Caesalpinia spinosa or tara (CS) & Caesalpinia decapetala (CD) leaves were evaluated for their ability to inhibit lipid oxidation using oil-in-water (O/W) emulsions as the model system. Liquid chromatography (LC) combined with mass spectrometry (MS), using a hybrid quadrupole time-of-flight (QTOF) mass spectrometer, was employed for (1) the identification of potential antioxidant species in the extracts & (2) to follow their evolution through aging of the emulsions.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.