Capsicum chinense (Chilli) : medicinal properties in alcoholic extraction

Capsicum chinense (Chilli, Piman, Piment) — family Solanacées.

Scientific synonyms : Capsicum sinense-Murray.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 24 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for colorectal carcinoma

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to CHEI-Guerrero LD (2022)

     Excerpt The extract of leaves of plants grown on black soil obtained by maceration displayed selective high cytotoxicity against colorectal cancer cells, IC50 HCT–15 = 16.23 ± 2.89 µg mL⁻¹. Capsicum chinense J., also known locally as habanero pepper, is a medicinal herb known for its pharmacological properties.

   • According to Basharat S (2020)

     Excerpt The domesticated species include Capsicum annuum, Capsicum frutescens, & Capsicum chinense. Capsaicinoids are believed to have strong pharmacological properties that could be used in pain relief, weight reduction, cardiovascular conditions, & cancer prevention besides providing relief in gastrointestinal diseases.

2. 2

   Oxidative stress

   Plant part used: fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Basharat S (2020)

     Excerpt The domesticated species include Capsicum annuum, Capsicum frutescens, & Capsicum chinense. TRPV1 is essential for the reduction of oxidative stress, pain sensations, & inflammation.

   • According to Bultimea-Cantua GV (2022)

     Excerpt In this work, the effect of the ethanolic extract of Capsicum chinense & Piper nigrum fruits, capsaicin, & piperine on the expression of the aflE, aflG, aflH, aflI, aflK, aflL, aflO, aflP, & aflQ genes involved in the aflatoxin biosynthetic pathway in Aspergillus parasiticus were studied by qRT-PCR analysis. In conclusion, the capsaicin & piperine, two antifungal & anti-aflatoxigenic compounds produce an up-regulation of antioxidant defense genes accompanied by an enhancement of catalase enzymatic activity in A.

   • According to Santos LS (2021)

     Excerpt This study aimed at determining the chemical profile of the ethanolic extract from Capsicum chinense Jacq. High antioxidant activity of EECC was expressed as IC50 values for reagents DPPH (IC50 = 18.04 µg/mL), ABTS (IC50 = 25.33 µg/mL) & FRAP (IC50 = 128.58 µg/mL).

   • According to Bertao RM (2016)

     Excerpt C chinense showed the lowest level of total phenols & flavonoids despite expressive antioxidant activity. praetermissum) were investigated for total phenolics, flavonoids, capsaicinoids contents & antioxidant activity objectifying to determine the relations between these bioactive compounds & the antioxidant capacity & also examine its cytotoxic & genotoxic potential.

   • According to Avilés-Betanzos KA (2022)

     Excerpt The results showed that NADES leads to extracts with significantly higher TPC, higher concentrations of individual polyphenols (gallic acid, protocatechuic acid, chlorogenic acid, cinnamic acid, coumaric acid), vitamin C &, finally, higher antioxidant capacity (9.55 ± 0.02 eq mg Trolox/g DM) than UAE extraction performed with methanol as the solvent. Thus, the aim of this study was to assess the antioxidant capacity, total polyphenol content (TPC), the phenolic profile & vitamin C content in extracts obtained from by-products (stems & leaves) of two varieties (Mayapan & Jaguar) of habanero pepper by ultrasound-assisted extraction (UAE) using natural deep eutectic solvents (NADES).

3. 3

   Atopic dermatitis, psoriasis

   Plant part used: fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Basharat S (2020)

     Excerpt The domesticated species include Capsicum annuum, Capsicum frutescens, & Capsicum chinense. The Capsicum genus is the only peppers plant that produces alkaloids carotenoids & flavonoids & capsaicinoids together.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.