Christia vestertillionis (Zèl-papiyon) : medicinal properties in alcoholic extraction

Christia vestertillionis (Zèl-papiyon, Butterfly wings, Ailes à-papillon) — family Fabacées.

Scientific synonyms : Hedysarum vespertilionis-L.f., Lourea vespertilionis-(L.f.) -Desv..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 48 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for liver and breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Nurul S.A.S (2018)

     Excerpt In contrast to kidney, liver tissues showed significant differences (p < 0.05) in lesions observed in low dose (430 mg), medium dose (700 mg) & high dose (1480 mg) groups with very mild, mild & mild to moderate lesion of hepatic necrosis, in the respective groups, & very mild hepatic degeneration & hepatitis were scored in all three groups. The term Butterfly tea refers to decoction of Mariposa christia vespertilionis leaves which is widely consumed by cancer patients throughout Malaysia & has gained a huge popularity among Malaysians, not only cancer patients but also researchers to discover the real potential of this plant.

   • According to Nurul SAS (2022)

     Excerpt The histopathology results showed there was significant (p<0.05) hepatic necrosis (mild to moderate) & degeneration (very mild) of liver tissue in the treated group (2000 mg/kg) affecting the periportal area. This study aims to evaluate the possible in vivo toxicity in 14-day acute & 90-day subchronic oral toxicity of ethanolic extract Christia vespertilionis (L.f.) Bakh.

   • According to Author (n.d.)

     Excerpt Christia Vespertilionis side-effects: In an experiment, samples of the liver that have been treated with the C. The degeneration of liver cells is caused by excess accumulation of glycogen, predominantly of the monoparticulate form, following consumption of low doses of the extract.

   • According to Nurul S (2021)

     Excerpt However, significant (p<0.05) differences were observed for hepatic necrosis & number of activated Kupffer cells in all herbal treated groups compared to control (from very mild to moderate scores). In conclusion, mixtures of CV & MC induced hepatotoxicity & renal toxicity, & the no-observed-adverse-effect levels (NOAEL) of CV & MC mixture is lower than 150 mg/kg.

   • According to Jining J (2020)

     Excerpt The cytotoxic effects were determined using MTT assay against human breast carcinoma cell lines (MCF-7 & MDA-MB-231). The study showed the root extracts of CV to possess notable anti-breast cancer effects.

2. 2

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Zambari IF (2023)

     Excerpt Green leaf had the highest anti-inflammation potential, with a high extraction yield (6.39 ± 0.01%), phenolic content (29.25 ± 0.50 mg) gallic acid equivalent [GAE]/mL), flavonoid content (1.57 ± 0.03 mg quercetin acid equivalent [QE]/mL) & tannin content (22.70 ± 3.15 mg tannic acid equivalent [TAE]/ mL). The protease inhibition assay showed that green leaf had anti-inflammatory activity at 66.55 ± 2.59% with the half-maximal inhibitory concentration (IC 50) of 284.59 ± 10.63 µg/mL.

   • According to Osman M.S (2017)

     Excerpt The findings of this study indicates the global yield of the MCV oils is 31 mg/g while the compound identification indicates the presence of anti-cancer, anti-inflammatory & beneficial phytochemicals. At present time, Mariposa Christia Vespertillonis (MCV) leave has become popular for its anti-cancer and thus is used widely among the traditional medicine in Malaysia.

   • According to Author (n.d.)

     Excerpt vespertilionis extract exhibited signs of necrosis, degeneration & inflammation in the histopathology examination. Christia Vespertilionis side-effects: In an experiment, samples of the liver that have been treated with the C.

   • According to Abu-Bakar FIB (2020)

     Excerpt Six selected plants were screened for their anti-gout activity in vitro of which three plants (i.e., Euphorbia hirta, Strobilanthes crispa & Christia vespertilionis) were further analyzed for their optimum extraction conditions using RSM. Gout is a type of arthritis that causes painful inflammation in joints due to the elevation of uric acid in the blood.

   • According to Jining J (2020)

     Excerpt Its herbal decoction was believed to show anti-inflammatory & anti-cancer effects. Christia vespertilionis, commonly known as ‘Daun Rerama’, has recently garnered attention from numerous sources in Malaysia as an alternative treatment.

3. 3

   Oxidative stress

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (2017)

     Excerpt The percentage of inhibition in antioxidant showed that ethyl acetate extract was the highest & SFE without ethanol co-solvent the lowest. The antioxidant activity on the extracts were tested using free radical scavenging activity of 1,1-diphenyl-2-picrilhydrazyl (DPPH) assay as well as to determine phytochemical components, alkaloid & flavonoid using the suitable chemical tests.

   • According to Ariff MAM (2019)

     Excerpt The objective of this study is to optimize the antioxidant components (based on antioxidant activity analysis) from the MCV leaves extract using Supercritical Fluid Extraction (SFE) based on different temperature, pressure, & particle size via Response Surface Methodology (RSM). The predicted RSM optimal condition of antioxidant activity was at temperature 50 °C, pressure 282 bar, & particle size 500 μm, which the predicted antioxidant was 50.62 %.

   • According to Ibrahim Farrah S (2022)

     Excerpt Results show that to date, phytochemicals such as alkaloids, flavonoids, quinones, & others have been identified, corresponding to its range of pharmacological activities that include anti-cancer, anti-malaria, & antioxidant. Commonly referred to as ‘daun rerama’, Christia vespertilionis has increased in popularity in traditional & modern medicine.

   • According to Jusoh HM (2019)

     Excerpt Jusoh HM et al, the total phenolic contents & antioxidant scavenging capacity in free & bound extracts of Christia vespertilionis (Daun rerama).

   • According to Shukri N.SSM (2019)

     Excerpt All the extracts were assessed for 2, 2-diphenyl-1-pierylhydrazyl (DPPH) scavenging ability & ferric reducing antioxidant power (FRAP) followed by Fourier transform infrared analysis. Christia vespertilionis or butterfly wings is widely found in South East Asia, traditionally used for many medical benefits.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.