Cinnamomum camphora (Kanf) : medicinal properties in alcoholic extraction

Cinnamomum camphora (Kanf, Camphor, Camphre) — family Lauracées.

Scientific synonyms : Camphora camphora (L.) H.Karst., C Vera-Raf, Cinnamomum officinarum Nees ex Steud., Laurus camphora-L, Persea camphora (L.) Spreng.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 55 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of colorectal carcinoma (p53 mutations) and fibrosarcoma,

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Nam GH (2019)

     Excerpt In previous study, about 50% of cancer cells have p53 mutations. Our data reveal that CC ethanol extract inhibits the cancer cell growth of both p53 gene wild type HCT 116 human colon cancer cells & p53 gene mutation type HT-29 human colon cancer cells.

   • According to Sharifi-Rad J (2021)

     Excerpt The results showed that the bioactive compounds of Cinnamomum species possess antimicrobial, antidiabetic, antioxidant, anti-inflammatory, anticancer & neuroprotective effects. The aim of this comprehensive and updated review is to summarize the biodiversity of the genus Cinnamomum, its bioactive compounds, the mechanisms that underlie the pharmacological activities & molecular targets & toxicological safety.

   • According to Hamidpour R (2013)

     Excerpt Camphor (Cinnamomum camphora) is obtained from the wood of camphor tree. In this paper our focus is on the use of camphor as a remedy for daily minor problems as well as reporting some information about the new applications of this traditional medicine to treat or prevent some serious life-threatening diseases sucha as cancer & diabetes.

   • According to Moavedi Y (2019)

     Excerpt Bioactive derivatives from the camphor laurel tree, Cinnamomum camphora, are posited to exhibit chemopreventive properties but the efficacy & mechanism of these natural products are not fully understood. We tested an essential-oil derivative, camphor white oil (CWO), for anti-tumor activity in a mouse model of keratinocyte-derived skin cancer.

   • According to Kim GY (2018)

     Excerpt Kim GY et al, Cinnamomum Camphora, a tranditional medicinal herb, is induces Apoptotic Cell death via Akt/MDM2/p53-dependent pathway in HCT 116 Human Colon Cancer, Hannam Univ, 2018-Abstract:.

2. 2

   Bacterial infection: Escherichia coli, Staphylococcus aureus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Yu Y (2021)

     Excerpt coli was treated with water, acetone & Cinnamomum camphora essential oils, respectively. In recent years, the overuse of antibiotics has led to an increase in antimicrobial resistance, which greatly reduces the efficacy of antibacterial drugs and affects people's health.

   • According to Ho CL (2009)

     Excerpt In this study, we used hydrodistillation & headspace GC methods to separate essential oils from the leaves, flowers and twigs of a ”linalool tree” (Cinnamomum camphora Sieb. Therefore, in addition to being raw materials for producing high-grade fragrance agents, these oils are also applicable to the antioxidant & antifungal purposes & exhibit the multipurpose potential of expanded essential oil applications.

   • According to Sharifi-Rad J (2021)

     Excerpt The results showed that the bioactive compounds of Cinnamomum species possess antimicrobial, antidiabetic, antioxidant, anti-inflammatory, anticancer & neuroprotective effects. The aim of this comprehensive and updated review is to summarize the biodiversity of the genus Cinnamomum, its bioactive compounds, the mechanisms that underlie the pharmacological activities & molecular targets & toxicological safety.

   • According to Zhou HX (2016)

     Excerpt The essential oil from CC had different degrees of inhibition on Escherichia coli,Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis. To determine the optimum extract condition of essential oil from dry Cinnamomum camphora leaves & to study its antibacterial activity.

   • According to Wang L (2020)

     Excerpt Escherichia coli is one of the most common microbial pathogens & frequently causes biofilm-associated opportunistic infections, such as diarrhea, endometritis & mastitis. coli biofilm formation, & bacterial killing occurred during the first 30 min of exposure to subinhibitory biofilm concentrations of CCEO.

3. 3

   Fungal infection: Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ho CL (2009)

     Excerpt In this study, we used hydrodistillation & headspace GC methods to separate essential oils from the leaves, flowers and twigs of a ”linalool tree” (Cinnamomum camphora Sieb. Therefore, in addition to being raw materials for producing high-grade fragrance agents, these oils are also applicable to the antioxidant & antifungal purposes & exhibit the multipurpose potential of expanded essential oil applications.

   • According to Sharifi-Rad J (2021)

     Excerpt The results showed that the bioactive compounds of Cinnamomum species possess antimicrobial, antidiabetic, antioxidant, anti-inflammatory, anticancer & neuroprotective effects. The aim of this comprehensive and updated review is to summarize the biodiversity of the genus Cinnamomum, its bioactive compounds, the mechanisms that underlie the pharmacological activities & molecular targets & toxicological safety.

   • According to Yu Y (2021)

     Excerpt In recent years, the overuse of antibiotics has led to an increase in antimicrobial resistance, which greatly reduces the efficacy of antibacterial drugs and affects people's health. coli was treated with water, acetone & Cinnamomum camphora essential oils, respectively.

   • According to Zhou HX (2016)

     Excerpt To determine the optimum extract condition of essential oil from dry Cinnamomum camphora leaves & to study its antibacterial activity. Conclusion: Subcritical fluid is suitable for the extraction of essential oil from CC & the essential oil has a good antimicrobial activity.

   • According to Kumar PD (2021)

     Excerpt Cinnamomum camphora L. The EOs were extracted by hydrodistillation with a Clevenger apparatus & their compositions were evaluated through gas chromatography-mass spectrometry (GC-MS), enantiomeric composition by chiral GC-MS, & antimicrobial properties were assayed by measuring minimum inhibitory concentrations (MICs).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.