Cissus quadrangularis (Sèt-don) : medicinal properties in alcoholic extraction

Cissus quadrangularis (Sèt-don, Minôt, Seven gifts, Handcuffs, Sept dons, Menottes) — family Vitacées.

Scientific synonyms : C. quadrangularis-Salisb, Vitis quadrangularis –(L)-Wall ex. W & A.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 20 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 109 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Diabetic nephropathy

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Syed AH (2021)

     Excerpt Accordingly, we aimed to delineate the protective effect of ethanolic extract of Cissus quadrangularis (EECQ) against high-fat diet/streptozotocin (HFD/STZ) induced diabetic nephropathy rats. Cissus quadrangularis, holds antioxidant & hypoglycemic activity; however, a direct link between its activity & prevention of diabetic nephropathy has not been ascertained yet.

   • According to Lekshmi RK (2014)

     Excerpt This study was aimed at evaluating the beneficial effects of Cissus quadrangularis stem extract on antioxidant/oxidant status in diabetes mellitus. Materials & methods: The antioxidant activities of an ethyl acetate fraction of Cissus quadrangularis stem (CQSF) at three different doses (50, 100, & 200 mg/kg body weight) were evaluated in rats with experimentally induced diabetes.

   • According to Gupta M (2018)

     Excerpt Alloxan (dissolved in 0.1 M citrate buffer (pH = 4.5); intraperitoneally injected @ 130 mg/kg body weight) induced type I diabetic rats were treated with individual & combined doses of ethanol extracts of CQ & TFG for consecutive 30 days @ 250 & 500 mg per kg body weight, orally. CQ & TFG combination therapy showed a marked improvement in bone microarchitecture & can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.

   • According to Chaudhari RL (2013)

     Excerpt The present study was performed to explore the antihyperglyceamic activity of ethanolic extract of leaves of Cissus quadrangularis against alloxan induced diabetic rats. quadrangularis & glyburide were administered orally in alloxan induced diabetic rats.

   • According to SRIVASTAVA AK (2011)

     Excerpt Jl of Pharm Res, 4(11) :3873-4, 2011-Abstract Cissus quadrangularis (Family-Vitaceae) is found in hotter parts of India & neibouring countries like Pakistan, Sri Lanka, & Malaysia. SRIVASTAVA AK et al, Antidiabetic activity of the stem extracts of Cissus quadrangularis Linn.

2. 2

   Type 1 diabetes mellitus

   Plant part used: Stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gupta M (2018)

     Excerpt Alloxan (dissolved in 0.1 M citrate buffer (pH = 4.5); intraperitoneally injected @ 130 mg/kg body weight) induced type I diabetic rats were treated with individual & combined doses of ethanol extracts of CQ & TFG for consecutive 30 days @ 250 & 500 mg per kg body weight, orally. CQ & TFG combination therapy showed a marked improvement in bone microarchitecture & can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.

   • According to Syed AH (2021)

     Excerpt Accordingly, we aimed to delineate the protective effect of ethanolic extract of Cissus quadrangularis (EECQ) against high-fat diet/streptozotocin (HFD/STZ) induced diabetic nephropathy rats. Cissus quadrangularis, holds antioxidant & hypoglycemic activity; however, a direct link between its activity & prevention of diabetic nephropathy has not been ascertained yet.

   • According to Chaudhari RL (2013)

     Excerpt The present study was performed to explore the antihyperglyceamic activity of ethanolic extract of leaves of Cissus quadrangularis against alloxan induced diabetic rats. quadrangularis & glyburide were administered orally in alloxan induced diabetic rats.

   • According to SRIVASTAVA AK (2011)

     Excerpt SRIVASTAVA AK et al, Antidiabetic activity of the stem extracts of Cissus quadrangularis Linn. Jl of Pharm Res, 4(11) :3873-4, 2011-Abstract Cissus quadrangularis (Family-Vitaceae) is found in hotter parts of India & neibouring countries like Pakistan, Sri Lanka, & Malaysia.

   • According to Syed AH (2022)

     Excerpt Insulin resistance (IR) is a significant complication in menopausal women, which predisposes them to cardiovascular disorder, obesity, & diabetes. Cissus quadrangularis is a polyphenolic plant rich in nutrients & is used as an edible vegetable in Nigeria.

3. 3

   Type II diabetes mellitus

   Plant part used: Stem.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gupta M (2018)

     Excerpt Alloxan (dissolved in 0.1 M citrate buffer (pH = 4.5); intraperitoneally injected @ 130 mg/kg body weight) induced type I diabetic rats were treated with individual & combined doses of ethanol extracts of CQ & TFG for consecutive 30 days @ 250 & 500 mg per kg body weight, orally. CQ & TFG combination therapy showed a marked improvement in bone microarchitecture & can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.

   • According to Syed AH (2021)

     Excerpt Accordingly, we aimed to delineate the protective effect of ethanolic extract of Cissus quadrangularis (EECQ) against high-fat diet/streptozotocin (HFD/STZ) induced diabetic nephropathy rats. Cissus quadrangularis, holds antioxidant & hypoglycemic activity; however, a direct link between its activity & prevention of diabetic nephropathy has not been ascertained yet.

   • According to Chaudhari RL (2013)

     Excerpt The present study was performed to explore the antihyperglyceamic activity of ethanolic extract of leaves of Cissus quadrangularis against alloxan induced diabetic rats. quadrangularis & glyburide were administered orally in alloxan induced diabetic rats.

   • According to SRIVASTAVA AK (2011)

     Excerpt SRIVASTAVA AK et al, Antidiabetic activity of the stem extracts of Cissus quadrangularis Linn. Jl of Pharm Res, 4(11) :3873-4, 2011-Abstract Cissus quadrangularis (Family-Vitaceae) is found in hotter parts of India & neibouring countries like Pakistan, Sri Lanka, & Malaysia.

   • According to Syed AH (2022)

     Excerpt Insulin resistance (IR) is a significant complication in menopausal women, which predisposes them to cardiovascular disorder, obesity, & diabetes. Cissus quadrangularis is a polyphenolic plant rich in nutrients & is used as an edible vegetable in Nigeria.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.