Citrullus lanatus (Watermelon) : medicinal properties in alcoholic extraction

Citrullus lanatus (Watermelon, Pastèk, Pastèque) — family Cucurbitacées.

Scientific synonyms : Ang Anguria citrullus Mill., Citrullus anguria (Duch) H.Hara, C aquosus Schur in Enu Pl. Transsilv, C lanatus subsp. cordophanus (M & L), C lanatus slan subsp. vulgaris (Schrad.) Fursa, (M & L), Cucurbita pinnatifida Schrank.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 55 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Complications of diabetes: renal tubular necrosis, hepatic cell damage (Kupffer cells),

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Jibril MM (2022)

     Excerpt The present research aimed to investigate the attenuative effects of watermelon (Citrullus lanatus) leaf extract on biochemical a&histological parameters in a high-fat diet combined with a low-dose streptozotocin (HFD/STZ)-induced type 2 diabetes mellitus. Hence, CL leaf could be an excellent candidate to be developed as a functional food ingredients or nutraceuticals for holistic management of diabetes mellitus & its complications.

   • According to Jiyun A (2011)

     Excerpt At the end of 4 weeks, mice were administrated with streptozotocin (40 mg/kg, i.p.) for 5 consecutive days to induce diabetes. the anti-diabetic potential of watermelon (Citrullus vulgaris Schrad) was evaluated in vivo.

   • According to Ajiboye BO (2020)

     Excerpt Ajiboye BO et al, Antidiabetic activity of watermelon (Citrullus lanatus) juice in alloxan-induced diabetic rats. J of Diabetes & Metabolic Disorders, 19(1), 343–52, 2020-.

   • According to Enemali MO (2020)

     Excerpt Photomicrograph images showed normal liver morphology in the control groups 1 & 3, 200 mg/kg mesocarp & 400 mg/kg seed extract administered groups, indicating that the two extract doses better protected the liver against damage occasioned by acetaminophen. lanatus fruit’s endocarp/exocarp, mesocarp & seed extracts on the liver of albino rats.

   • According to Zamuz S (2021)

     Excerpt Watermelon (Citrullus lanatus) represents the largest cultivated member of the Cucurbitaceae family, showing great relevance from the economic point of view & largely consumed around the world accounting for about 7% of the world area dedicated to the production of vegetables, with 67% of the total quantity produced in China.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Jibril MM (2022)

     Excerpt The present research aimed to investigate the attenuative effects of watermelon (Citrullus lanatus) leaf extract on biochemical a&histological parameters in a high-fat diet combined with a low-dose streptozotocin (HFD/STZ)-induced type 2 diabetes mellitus. Hence, CL leaf could be an excellent candidate to be developed as a functional food ingredients or nutraceuticals for holistic management of diabetes mellitus & its complications.

   • According to Jiyun A (2011)

     Excerpt At the end of 4 weeks, mice were administrated with streptozotocin (40 mg/kg, i.p.) for 5 consecutive days to induce diabetes. the anti-diabetic potential of watermelon (Citrullus vulgaris Schrad) was evaluated in vivo.

   • According to Ajiboye BO (2020)

     Excerpt Ajiboye BO et al, Antidiabetic activity of watermelon (Citrullus lanatus) juice in alloxan-induced diabetic rats. J of Diabetes & Metabolic Disorders, 19(1), 343–52, 2020-.

3. 3

   Pain, hyperalgesia

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gill N (2010)

     Excerpt Gill N et al, Evaluation of antioxidant, anti-inflammatory & analgesic potential of Citrullus lanatus seed extract in rodent model.

   • According to Wahid S (2020)

     Excerpt melo & CL may be effectively used as adjuvant analgesic & anti-inflammatory agents in situation of chronic pain & inflammation. this study was designed to evaluate analgesic, anti-inflammatory & toxic effects of Cucumis melo & Citrullus lanatus.

   • According to Walid M (2022)

     Excerpt Citrullus lanatus (Thunb.) is a member of the Cucurbitaceae family, commonly farmed as an edible vegetable around the globe. Those are members of calcium mediate signaling, cholinergic synapse, regulation of cytosolic calcium concentration, smooth muscle contraction, & inflammatory responses.

   • According to Walid M (2022)

     Excerpt Citrullus lanatus (Thunb.) belongs to the ground family, Cucurbitaceae, known for edible fruit. Results: In silico studies revealed that bioactive compounds of CL seeds interfere with asthma & diarrhea-associated target genes, which are a member of calcium mediate signaling, regulation of cytosolic calcium concentration, smooth muscle contraction, & inflammatory responses.

   • According to Feyisayo (n.d.)

     Excerpt Feyisayo et al, Anti-hyperglycaemic, anti-inflammatory & anti-oxidant activities of Carica papaya & Citrullus lanatus seeds, Ife J.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.