Citrus x (Sitwon-frans) : medicinal properties | Lapo

Citrus x (Sitwon-frans) — family Rutacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The monograph draws on 83 scientific references recorded for the species.

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. 1

   Liver disorders

   Plant part used: Fruit. Documented pharmacological profile: Silymarine-like.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mahmoud MF (2014)

     Excerpt Limonin ameliorated the deleterious effects of I/R as indicated by improvement in liver function tests. Limonin has been shown to exhibit anti-inflammatory & antioxidant properties in the settings of chemically induced hepatic injury.

   • According to Anandakumar P (2021)

     Excerpt This review provides worthy information about the beneficial effects of D-limonene such as antioxidant, antidiabetic, anticancer, anti-inflammatory, cardioprotective, gastroprotective, hepatoprotective, immune modulatory, anti-fibrotic, anti-genotoxic etc.

2. 2

   Cancer

   Plant part used: Fruit. Documented pharmacological profile: Capecitabine-like.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Anandakumar P (2021)

     Excerpt This review provides worthy information about the beneficial effects of D-limonene such as antioxidant, antidiabetic, anticancer, anti-inflammatory, cardioprotective, gastroprotective, hepatoprotective, immune modulatory, anti-fibrotic, anti-genotoxic etc.

   • According to Cirmi S (2017)

     Excerpt Search terms included Citrus, Citrus aurantifolia, Citrus sinensis, Citrus paradisi, Citrus fruits, Citrus fruits extract, cancer, neoplasm, neoplasia, tumor, metastasis, carcinogenesis, proliferation. Objective: To summarize the numerous evidences on the potential of Citrus juice & their extracts as anticancer agents.

3. 3

   Oxidative stress

   Plant part used: Fruit. Documented pharmacological profile: Acide ascorbique-like, Rutin-like.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Wang Y (2022)

     Excerpt Citrus flavonoids play an essential role in regulating oxidative stress & are an important source of daily intake of antioxidant supplements. The antioxidant ability is the link & bridge connecting a variety of biological activities.

   • According to Martí N (2009)

     Excerpt Their antioxidant activity & related benefits derive not only from VC but also from other phytochemicals, mainly flavonoids.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.