Clidemia hirta (Prino) : medicinal properties in alcoholic extraction

Clidemia hirta (Prino, bonbon-mèl, Zo-mannikou, Pruneau) — family Melastomacées.

Scientific synonyms : Clidemia crenata-(Vahl)-DC, Maieta hirta-(L)-Baill, Melastoma crenatum-Vahl, M elegans-Aubl, Staphidum pauciflorum-Desr, S tiliflorum-(Desr)-N.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 11 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for ascites-associated lymphoma

   Plant part used: sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to NARASIMHAM DOKKA (2017)

     Excerpt Results: We found that the ethanol extract had higher inhibition activities against Dalton’s Lymphoma ascites (DLA) cancer cell line, 50% DLA cell line inhibition at 68µg/ml, while 50% inhibition by petroleum ether & chloroform extracts were at 160µg/ml & 172µg/ml, respectively. To evaluate the anticancer & antioxidant activity of medicinal plant Clidemia hirta extracted in different solvents.

   • According to Amzar N (2017)

     Excerpt Clidemia hirta possesses many medicinal properties for healing several diseases and for health maintenance. Various biochemical changes associated with liver damage & oxidative stress were measured.

2. 2

   Bacterial infection: Bacillus subtilis, Vibrio cholerae

   Plant part used: sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rahayu E (2021)

     Excerpt One of the antibacterial potentials that can reduce the activity of pathogenic bacteria is the leaf extract of Clidemia hirta. The test bacteria used were Vibrio cholerae ATCC 39315 & Bacillus cereus ATCC 14574.

   • According to Abdellaoui SEl (2014)

     Excerpt Abdellaoui SEl et al, Centrifugal partition chromatography for antibacterial bio-guided fractionation of Clidemia hirta roots.

   • According to LOPEZ T (2016)

     Excerpt Clidemia hirta L., un arbuste tropical utilisé en médecine traditionnelle dans de nombreux pays, pourrait constituer une ressource intéressante pour des applications cosmétiques. hirta in vitro a été utilisée pour évaluer l'influence des milieux de culture sur la croissance des plantes ainsi que le contenu phytochimique et les activités antioxydantes et antibactériennes des extraits de leurs feuilles.

   • According to DIANITA R (2011)

     Excerpt Clidemia hirta (L.) D. Thus, this study was conducted to investigate the antibacterial properties of this species & determine its MIC towards several bacteria, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa.

   • According to Ismail NH (2022)

     Excerpt The broad-leaved weeds Melastoma malabthricum, Clidemia hirta, Chromolaena odorata, & Ageratum conyzoides are characterized as potential weeds due to their high nutritional value & abundance of chemical components for different bioactivities. Some types of compounds found are known to have the potential as antibacterial, antiviral, antioxidant, insecticidal, & other.

3. 3

   Oxidative stress

   Plant part used: sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Amzar N (2017)

     Excerpt The development of oxidative stress was observed through the escalation of hepatic lipid peroxidation, depletion of glutathione, & reduced antioxidant enzymes (glutathione peroxidase, glutathione reductase, catalase, glutathione S-transferase & quinone reductase). Clidemia hirta possesses many medicinal properties for healing several diseases and for health maintenance.

   • According to NARASIMHAM DOKKA (2017)

     Excerpt To evaluate the anticancer & antioxidant activity of medicinal plant Clidemia hirta extracted in different solvents. Methods: Crude extracts were prepared from the leaves of Clidemia hirta using ethanol, petroleum ether & chloroform solvents.

   • According to Azahar N (2019)

     Excerpt The results show all Melastoma family species have wide range of absorbance such as UVA, UVB & UVB radiation & exhibit good SPF number where Clidemia hirta leaves extract ethyl acetate recorded to have highest SPF value among others. Meanwhile, the three of antioxidant assay shows that C hirta ethyl acetate displays higher antioxidant activity against DPPH radical & contain higher phenolic and FRAP value as compared to other Melastoma species.

   • According to LOPEZ T (2016)

     Excerpt Clidemia hirta L., un arbuste tropical utilisé en médecine traditionnelle dans de nombreux pays, pourrait constituer une ressource intéressante pour des applications cosmétiques. hirta in vitro a été utilisée pour évaluer l'influence des milieux de culture sur la croissance des plantes ainsi que le contenu phytochimique et les activités antioxydantes et antibactériennes des extraits de leurs feuilles.

   • According to Junedi S (2023)

     Excerpt Ethanol extracts from the leaves of Clidemia hirta (L.) D. hirta extract showed a higher SPF value in UV spectrophotometry, and antiglycation activity through bovine serum albumin-glucose (BSAglucose) method, than the M.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.