Clitoria ternatea (Blue wheat) : medicinal properties in alcoholic extraction

Clitoria ternatea (Blue wheat, Blue pea, Blue bindweed, Pwa-blé, Lizwon blé, pois bleu, Liseron bleu) — family Convolvulacées.

Scientific synonyms : Clitoria albiflora Mattei, C bracteata Poir., C mearnsii De Wild., C tanganicensis Micheli, C zanzibarensis Vatke.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 34 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 179 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Neurological disorders in people with diabetes; prevention of juvenile diabetic encephalopathy

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mathada RV (2012)

     Excerpt CONCLUSION: The alcoholic root extract of herb C ternatea has shown significant gross impact in preventing the possible complications related to brain hippocampal area CA 3 & pancreatic tissue in juvenile diabetic rat experimental models. Encephalopathy is a major complication in juvenile diabetes mellitus which cripples the potential physio morphological growth & development in early childhood.

   • According to Chayaratanasin P (2015)

     Excerpt CONCLUSIONS: The results showed that CTE has strong antiglycation & antioxidant properties & might have therapeutic potentials in the prevention of AGE-mediated diabetic complications. Clitoria ternatea extract (CTE) has been demonstrated to possess anti-diabetic activity.

   • According to Ravishankar MV (2013)

     Excerpt To study the effect of herbal alcoholic root extract of Clitoria ternatea on the neurons of frontal cortex & dentate gyrus of young diabetic rats. Background: The brain is prone for adverse effects of early childhood diabetes which gradually can lead to diabetic encephalopathy.

   • According to Mehla J (2013)

     Excerpt ternatea (100, 300 & 500 mg/kg, p.o.) was selected for evaluation in intra-cerebro-ventricularly injected streptozotocin (STZ)-induced cognitive impairment in male Wistar rats. Clitoria ternatea, commonly known as Aparajita, is used as Medyha Rasayana in Ayurveda.

   • According to Rusmana D (2024)

     Excerpt Rats suffering from diabetes will be examined after being given oral doses of Simvastatin 0.9 mg/kg BW, Glibenclamide 0.45 mg/kg BW, & 200, 400, & 800 mg/kg BW CTE, model induced by streptozotocin. ternatea extract (CTE) in rats with diabetic complications related to dyslipidemia.

2. 2

   Diabetic foot

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Pakpahan FD (2023)

     Excerpt Moreover, the wound healing study showed CT flower ethanolic extract gel 15% exhibited the best wound healing activity in the diabetic animal model significantly (p<0.05) than negative, normal & test II, but not significantly different with positive & test I (p>0.05). We divided the animals into six groups, namely negative (placebo), positive (bioplacenton® gel), test I (Clitoria ternate L flower extract gel 5%), test II (Clitoria ternate L flower extract gel 10%), & test III (Clitoria ternate L flower extract gel 15%), & normal control group.

   • According to Kalyan BV (2011)

     Excerpt The leaves & flowers of Clitoria ternatea have been reported for antidiabetic activity, hence an attempt was made to evaluate the antidiabetic potential of seeds of C ternatea. The seed extracts at two dose levels like 200mg and 400mg/kg body weight were screened for hypoglycaemic activity in Streptozotocin induced diabetic rats (60mg/kg, i.p.).

   • According to Chusak C (2018)

     Excerpt The aim of this study was to determine the effects of C ternatea flower extract (CTE) on postprandial plasma glycemia response & antioxidant status in healthy men. Incremental postprandial plasma glucose, insulin, uric acid, antioxidant capacities & lipid peroxidation were measured during 3 h of administration.

   • According to Chayaratanasin P (2015)

     Excerpt Clitoria ternatea extract (CTE) has been demonstrated to possess anti-diabetic activity. CONCLUSIONS: The results showed that CTE has strong antiglycation & antioxidant properties & might have therapeutic potentials in the prevention of AGE-mediated diabetic complications.

   • According to Widowati W (2023)

     Excerpt Butterfly pea flower (Clitoria ternatea L.) extract (CTE) has pharmacological activities such as hepatoprotective, diuretic, antioxidant, antidiabetic, & anti-inflammatory activities. Diabetes Mellitus (DM) is hyperglycemic or elevated blood glucose level & deficiency of insulin level.

3. 3

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kavitha R (2019)

     Excerpt To investigate the effects of ethanolic extracts of leaf & fruit of Trichosanthes dioica & leaf of Clitoria ternatea were studied on the altered non-enzymatic antioxidant system such as reduced glutathione (GSH), Vitamin E, C & A in streptozotocin-induced diabetic Wistar rats. Group XI was treated with Glibenclamide (600 μg/kg body weight), a standard oral hypoglycemic drug used as a reference drug for comparison.

   • According to Talpate KA (2014)

     Excerpt Ethanol extract of Clitorea ternatea (EECT) was evaluated in diabetes-induced cognitive decline rat model for its nootropic & neuroprotective activity. Conclusions: The present data indicates that C ternatea tender’s protection against diabetes induced cognitive decline & merits the need for further studies to elucidate its mode of action.

   • According to Kavitha R (2020)

     Excerpt Trichosanthes dioica & Clitoria ternatea were traditional plants that were used for the treatment of diabetes mellitus, stress & depressant. The present work was undertaken to evaluate the antihyperlipidemic effect of individual & combined ethanolic extracts of these two different herbs to study the acute oral toxicity study, body weight, oral glucose tolerance test & serum lipids in normal & STZ-induced diabetic rats.

   • According to Ravishankar MV (2013)

     Excerpt To study the effect of herbal alcoholic root extract of Clitoria ternatea on the neurons of frontal cortex & dentate gyrus of young diabetic rats. Materials & methods: The diabetes was induced in 22 days (postnatal) Wistar rats by giving intraperitoneal injection of Streptozotocin at a dose of 60mg/kg body weight.

   • According to Verma P (2013)

     Excerpt The antidiabetic & antihyperlipidemic potential was evaluated in streptozotocin-induced diabetic rats & correlated with its in vivo & in vitro antioxidant activity. The aim of the present study was to investigate the pancreatic regeneration potential of different fractions of the ethanol extract Clitoria ternatea.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.