Codiaeum variegatum (Kroton) : medicinal properties in alcoholic extraction

Codiaeum variegatum (Kroton, Croton) — family Euphorbiacées.

Scientific synonyms : Codiaeum variegatum var. pictum (Lodd.) Müll.Arg., Codiaeum variegatum (L.) Blume, Croton pictus Lodd., Croton variegatus L..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 52 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Arthrobacter, Bacillus subtilis, Corynebacterium diphtheriae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Bhot M (2010)

     Excerpt Norwood beauty, Punctatum aureum & Undulatum, against six different bacterial strains including gram-positive bacteria Arthrobacter, Bacillus subtilis, Corynebacterium diphtheriae & gram-negative bacteria Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa was studied. The antibacterial activity of three varieties of Codiaeum variegatum (L.) Blume viz.

   • According to Gastador FT (2011)

     Excerpt This study aims to investigate the antibacterial activity of the test solutions prepared from the extracts of the fresh leaves of Codiaeum variegatum (Croton) against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis & Staphylococcus aureus using Kirby-Bauer Disc Diffusion method. This study dealt with the antibacterial activity of CV extract of the fresh leaves of the plant against four test microorganisms (Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus).

   • According to Author (1988)

     Excerpt The aim of this assay is to improve the Antifungal activity of Codiaeum variegatum leaf extract against Alternaria alternata, & b. It is also clear that the antifungal activity against Alternaria & Fusarium is relatively greater with the young & the mature leaf extracts respectively.

   • According to MOHAMED-NE (2018)

     Excerpt MOHAMED-NE et al: Chemical composition & antibacterial activity of Codiaeum variegatum leaves on Wistar albino rodents of both sexes.

   • According to Mohamed N E (2019)

     Excerpt Mohamed N E et al, Chemical composition & antibacterial activity of Codiaeum variegatum leaves Zagazig J.

2. 2

   Cancer: adjuvant treatment for liver, leukaemia and breast cancer

   Plant part used: Stem bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Anim M T (2016)

     Excerpt Hence, the objective of this research was to determine the phytochemical, total phenolic content, antioxidant & antiproliferative effect of Codiaeum variegatum crude extracts & fractions. Both crude extracts showed antiproliferative activity towards all cancer cell lines with the stem bark exhibiting the strongest cytotoxicity.

   • According to Pechangou Nsangou N (2023)

     Excerpt Codiaeum variegatum has been widely investigated for its biological proprieties ranging from the antiamoebic potential to the phytochemical analysis. Macrophages were treated with different concentrations (0.1; 1; 10 & 100 μg/mL) of the extracts/fractions for the inhibition of 5-lipoxygenase activity, nitric oxide (NO) & Tumor Necrosis Factor Alpha (TNF-α) production.

   • According to Pechangou Nsangou N (2023)

     Excerpt Codiaeum variegatum has been widely investigated for its biological proprieties ranging from the antiamoebic potential to the phytochemical analysis. Macrophages were treated with different concentrations (0.1; 1; 10 and 100 μg/mL) of the extracts/fractions for the inhibition of 5-lipoxygenase activity, nitric oxide (NO) & Tumor Necrosis Factor Alpha (TNF-α) production.

   • According to Suhiratwanich P (2023)

     Excerpt variegatum on three cancer cells, including human breast, human liver, & human cervical cancer cells. Codiaeum variegatum (L.) Blume is a well-known ornamental foliage plant used as a vegetable in northern Thailand, & it is the source of numerous bioactive substances.

   • According to Tolba SS (2024)

     Excerpt This study aimed to discover bioactive fatty esters in the n-hexane leaf extract of Codiaeum variegatum (L.) [ C.

3. 3

   Plant fungal diseases: Fusarium oxysporum, Alternaria alternata

   Plant part used: Pesticidal and veterinary use.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Author (1988)

     Excerpt The aim of this assay is to improve the Antifungal activity of Codiaeum variegatum leaf extract against Alternaria alternata, & b. It is also clear that the antifungal activity against Alternaria & Fusarium is relatively greater with the young & the mature leaf extracts respectively.

   • According to Bhot M (2010)

     Excerpt The antibacterial activity of three varieties of Codiaeum variegatum (L.) Blume viz. The antimicrobial activity was visually recorded by measuring zone of inhibition in millimeters.

   • According to MOHAMED-NE (2018)

     Excerpt MOHAMED-NE et al: Chemical composition & antibacterial activity of Codiaeum variegatum leaves on Wistar albino rodents of both sexes.

   • According to Mohamed N E (2019)

     Excerpt Mohamed N E et al, Chemical composition & antibacterial activity of Codiaeum variegatum leaves Zagazig J.

   • According to Sindy M (2022)

     Excerpt One kind of plant that can be utilized as an option is puring anting (Codiaeum variegatum var. The results of this study showed that the active fraction of puring anting leaves contained in the methanol fraction of 80%, & the aftereffects of the antibacterial test utilizing the circle dissemination test technique showed that the restraint of S.aureus E.coli respectively was 5.4000 ± 2.0553 mm.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.