Corchorus olitorius (Jit) : medicinal properties in alcoholic extraction

Corchorus olitorius (Jit, Jute) — family Malvacées.

Scientific synonyms : Corchorus malchairii-De Wild, C quinquelocuris-M, C fongicarpus-G D, C olitorius var incisifolius-A & S.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 65 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for hepatocellular carcinoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Biswas A (2022)

     Excerpt Results suggest that various phytochemicals such as cardiac glycosides, phenols, flavonoids, sterols, lipids, & fatty acids were found or analytically identified in different plant parts (leaf, stem, seed, & root), & many of them are responsible for pharmacological properties and their antitumor, anticancer, antioxidant, antinociceptive, anti-inflammatory, analgesic, antipyretic, antiviral, antibacterial, anticonvulsant, antidiabetic & antiobesity, & cardiovascular properties help to prevent & cure many chronic diseases. olitorius have broad applications ranging from textile to bio composite, & young leaves & shoots are used as healthy vegetables & have long been used as traditional remedies for fever, ascites, algesia, liver disorders, piles, & in many cultures.

   • According to Ismail EH (2018)

     Excerpt An in vitro cytotoxic assay of the biocompatible Au NPs revealed a strong cytotoxic activity in three human cancer cell lines, namely, colon carcinoma HCT-116, hepatocellular carcinoma HepG-2, & breast adenocarcinoma MCF-7. A facile bottom-up "green" synthetic route of gold nanoparticles (Au NPs) is described, using a leaf extract of the Malvaceae plant Corchorus olitorius as a reducing & stabilizing agent.

   • According to Gomaa AA (2019)

     Excerpt Histopathological examination of the liver revealed that C.O was more effective than orlistat in the alleviating of steatosis & adipocyte hypertrophy shown in obese control rats. To determine the efficacy of Corchorus olitorius leaf extract in the prevention of metabolic syndrome induced in rats by high-fat diet (HFD) & compare it with that of orlistat.

   • According to Adedosu OT (2015)

     Excerpt Corchorus olitorius is a household leafy vegetable with several medicinal uses. Furthermore, Extract at 100 mg/kg modulate sodium arsenite induced hepatotoxicity in rats, as combined treatment significantly (p<0.05) decreases cholesterol & marker enzymes activities (Alanine aminotransferase, Aspartate aminotransferase and Gamma glutamyl transferase) compared with intoxicated animals.

   • According to Do-Ho M (2021)

     Excerpt In this study, we investigated the protective effects of the water-soluble extract from molokhia (Corchorus olitorius) leaves (WM) on the alcohol-induced disruption of the gut-liver axis in mice. Gut microbial dysbiosis, induced by alcohol consumption, disrupts the gut-liver axis, leading to the development & progression of alcoholic liver disease.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Egua OM (2013)

     Excerpt The ethanolic seed extract of Corchorus olitorius was studied to ascertain its possible antidiabetic effect. The ethanolic seed extract of Corchorus olitorius was found to contain alkaloids, tannins, flavanoids, glycosides, saponin, cardiac glycosides, anthraquinones, steroids and volatile oil.

   • According to Olusanya AR (2018)

     Excerpt Ethanolic extract of Corchorus olitorius leaf was investigated for antidiabetic activity in alloxan-induced diabetic rats. Group B was diabetic untreated, group C was diabetic & treated with Glibenclamide, while groups D, E & F received the ethanolic extract of C.

   • According to Abdallah H (2020)

     Excerpt Therapies for diabetes mellitus are still meeting failure in most cases, especially in the developed stages of the disease due to incredible associating complications. AIM: We aimed to investigate the antidiabetic effects of one of the most popular plants cultivated in Egypt, Corchorus.

   • According to Gomaa AA (2019)

     Excerpt To determine the efficacy of Corchorus olitorius leaf extract in the prevention of metabolic syndrome induced in rats by high-fat diet (HFD) & compare it with that of orlistat. They exhibited a significant reduction in serum glucose, total cholesterol, triglycerides, low density lipoprotein cholesterol, free fatty acids, IL-1β, tumour necrosis factor-α (TNF-α), insulin & leptin levels of obese rat groups while high density lipoprotein cholesterol & adiponectin levels were significantly increased by them.

   • According to Saliu J.A (2015)

     Excerpt This study sought to evaluate the antidiabetic potentials of jute leaf (Corchorus olitorius) on low dose streptozotocin/high fat diet induced diabetic rats. The results showed that there was a significant increase (P<0.05) in the blood glucose, α-amylase, α-glucosidase, angiotensin-1-converting enzyme activities, lipid peroxidation in pancreas, total cholesterol & triglyceride levels in diabetic rats when compared to the normal (control) rats.

3. 3

   Bacterial infection: Bacillus subtilis, Klebsiella spp., Escherichia coli, Proteus vulgaris, Serratia marcescens, Enterococcus faecalis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Özdenefe S (2018)

     Excerpt the aim of this study was to determine the antimicrobial (antibacterial & antifungal) activity of the Corchorus olitorius leaf extracts, obtained from different regions of the Turkish Republic of Northern Cyprus. olitorius leaf displayed no antibacterial activity.

   • According to Mohammed R (2016)

     Excerpt The leaves extract of Corchorus olitorius, the family Malvaceae, are commonly called khudra, the plant extensively used in Sudanese traditional medicine. From the above-mentioned extract we prepare cream & ointment as antibacterial & antifungal dosage forms.

   • According to Author (2012)

     Excerpt Extracts were used to detect the inhibitory activity on gram’s negative and gram’s positive pathogenic bacteria, which include the following types: Klebsiella pneumoniae, Escherichia coli, proteus mirabilis, Serratia marcescuns, Aeromonas hydrophila Staphylococcus aureus & Streptococcus fecalis. The results of the inhibitory activity of alcoholic extracts depending on the different types of bacteria, & there was a clear increase in the rate of inhibition range with increasing the concentration of plant extracts against bacteria, All concentration of extracts were found to exhibit significant differences at level (p<0.05) by antimicrobial activity against most bacterial species.

   • According to Pal DK (2008)

     Excerpt The methanol extracts of Cuscuta reflexa stem & Corchorus olitorius seed showed a broad spectrum of antibacterial activity.

   • According to İLHAN S (2007)

     Excerpt İLHAN S et al, Antibacterial & Antifungal Activity of Corchorus olitorius L.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.