Coreopsis tinctoria (Tick seed) : medicinal properties in alcoholic extraction

Coreopsis tinctoria (Tick seed, Cat’s eye, Cat’s eyes, Grenn' tik, Zié-chat, graine-à- tique, Yeux-à-chat) — family Asteracées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 56 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Normalisation of serum parameters: elevated ALT, AST, ALP, SOD, GSH-Px and MDA

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Tsai JC (2017)

     Excerpt Conclusions: These results demonstrate the hepatoprotective effect of CT EtOH against CCl4-induced acute liver injury in mice, & the underlying hepatoprotective mechanisms are associated with antioxidant & anti-proinflammatory activities. The activities of antioxidant enzymes, namely superoxide dismutase & glutathione reductase, significantly increased after treatment with CTEtOH (0.5 & 1.0 g/kg) & that of glutathione peroxidase increased after treatment with 1.0 g/kg of CTEtOH.

   • According to Jiang BP (2006)

     Excerpt An infusion of Coreopsis tinctoria (CT) flowering tops is traditionally used in Portugal to control hyperglycemia; however, the effects of CT protection against high-fat diet (HFD)-induced hepatic insulin resistance have not been systematically studied & the precise mechanism of action is not clear. Serum samples for clinical biochemistry & liver samples for histopathology & liquid chromatography-mass spectrometry-based metabolomic research were collected.

   • According to Buweialiye H (2025)

     Excerpt To validate the anti-hepatocellular carcinoma (HCC) efficacy of Coreopsis tinctoria Total Flavonoids (CTFs) & explore its underlying mechanisms using a comprehensive approach integrating network pharmacology & experimental verification, thereby supporting its potential as a multi-target therapeutic agent for liver cancer.

   • According to Abdurehman D (n.d.)

     Excerpt Abdurehman D et al, Optimization of preparation method of hepatoprotective active components from Coreopsis tinctoria Nutt.

   • According to Wang T (2015)

     Excerpt Coreopsis tinctoria Nutt. C tinctoria produces a greater quantity and better quality of volatile components compared with two other Chrysanthemum tea materials (Chrysanthemum morifolium cv.

2. 2

   Diabetic retinopathy

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Cai W (2016)

     Excerpt In conclusion, CT flower extracts may ameliorate high-fat diet-induced hyperglycemia & insulin resistance. flower extracts on hyperglycemia of diet-induced obese mice & the underlying mechanisms.

   • According to Hui L (2021)

     Excerpt This study was intended to investigate the protective effect of the effective components of CT on the retinopathy of db/db diabetic mice & provide experimental basis for exploring the efficacy of CTT & the development of new drugs for the treatment of DR. Diabetic retinopathy (DR) is one of the main diabetic microvascular complications in clinical practice, which features a complicated mechanism & insignificant efficacy.

   • According to Yu Q (2022)

     Excerpt In folk medicine, the flower tea CT is often used as an adjunctive therapy for diabetes & Alzheimer's disease. Coreopsis tinctoria Nutt.

   • According to Lam SC (2016)

     Excerpt Coreopsis tinctoria, also called "snow chrysanthemum" in China, is a flower tea material that has been reported to possess excellent pharmacological properties such as antioxidant & antidiabetic activities. tinctoria and the related flower tea materials, Chrysanthemum morifolium cv "Hangju" & "Gongju," were in different clusters, & different parts (flowers, buds, seeds, stems, & leaves) of CT were obviously different.

   • According to Jiang BP (2006)

     Excerpt An infusion of Coreopsis tinctoria (CT) flowering tops is traditionally used in Portugal to control hyperglycemia; however, the effects of CT protection against high-fat diet (HFD)-induced hepatic insulin resistance have not been systematically studied & the precise mechanism of action is not clear. These results provide metabolic evidence of the complex pathogenic mechanism involved in hepatic insulin resistance & that the supplementation with CT improves insulin resistance at a global scale.

3. 3

   Type II diabetes mellitus

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Cai W (2016)

     Excerpt In conclusion, CT flower extracts may ameliorate high-fat diet-induced hyperglycemia & insulin resistance. flower extracts on hyperglycemia of diet-induced obese mice & the underlying mechanisms.

   • According to Yu Q (2022)

     Excerpt In folk medicine, the flower tea CT is often used as an adjunctive therapy for diabetes & Alzheimer's disease. Coreopsis tinctoria Nutt.

   • According to Lam SC (2016)

     Excerpt Coreopsis tinctoria, also called "snow chrysanthemum" in China, is a flower tea material that has been reported to possess excellent pharmacological properties such as antioxidant & antidiabetic activities. tinctoria and the related flower tea materials, Chrysanthemum morifolium cv "Hangju" & "Gongju," were in different clusters, & different parts (flowers, buds, seeds, stems, & leaves) of CT were obviously different.

   • According to Jiang BP (2006)

     Excerpt An infusion of Coreopsis tinctoria (CT) flowering tops is traditionally used in Portugal to control hyperglycemia; however, the effects of CT protection against high-fat diet (HFD)-induced hepatic insulin resistance have not been systematically studied & the precise mechanism of action is not clear. These results provide metabolic evidence of the complex pathogenic mechanism involved in hepatic insulin resistance & that the supplementation with CT improves insulin resistance at a global scale.

   • According to Dias T (2010)

     Excerpt flowering tops have been used traditionally in Portugal to control hyperglycaemia & a previous study revealed that daily administration of the infusion during a 3-week period promoted the recovery of glucose tolerance by a mechanism different from inhibition of glucose absorption & direct promotion of insulin secretion. infusions of Coreopsis tinctoria Nutt.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.