Cosmos caudatus (Margrit) : medicinal properties in alcoholic extraction

Cosmos caudatus (Margrit, Marguerite) — family Asteracées.

Scientific synonyms : Bidens artemilifolia Sb. B Capitata-(K)-Kz., berteriana-Sp., B carnea-H., Cosmos caudata-(Kunth)-Spreng.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 34 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for uterine carcinoma

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to NURHAYATI B (2018)

     Excerpt Cosmos caudatus ethanolic extract (CCEE) has been proved to have antioxidant effect that inhibited cancer cell growth due to its bioactive compounds such as catechin, quercetin & chlorogenic acid. CONCLUSION: CCEE has the lowest antioxidant activity compared to quercetin, catechin, & chlorogenic acid & has the lowest anticancer activity compared to quercetin.

   • According to SUSANTO S (2020)

     Excerpt Kenikir leaves (Cosmos caudatus) Has been used as traditional medicine, especially as an anti-cancer, this plant has been in Indonesia both in herbs & capsules. caudatus) as an anti-cancer based on cytotoxic activity using L1210 leukaemia cells.

   • According to FITA FFE (2015)

     Excerpt The purposes of this study are to measure the cytotoxic effect of methanol extracts of kenikir leaves & doxorubicin combination treatment against T47D breast cancer cell growth in-vitro & in-silico, as well as determining the optimal dose combination that produces the most potent cytotoxic effects. The cytotoxicity assay on the T47D breast cancer cells is carried out using MTT assay.

   • According to Pebriana R (2008)

     Excerpt It has been known that methanolic extract of kenikir (Cosmos caudatus Kunth) contain on some aglycone flavonoids & quercétine glycoside. This experiment was designed to know whether methanolic extract of CC leaves has capability of apoptotic stimulation on breast cancer cell line T47D.

2. 2

   Oxidative stress

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to NURHAYATI B (2018)

     Excerpt Cosmos caudatus ethanolic extract (CCEE) has been proved to have antioxidant effect that inhibited cancer cell growth due to its bioactive compounds such as catechin, quercetin & chlorogenic acid. Oxidative stress is closely related to all aspects of cancer.

   • According to SARI GM (2025)

     Excerpt Conclusion: These findings suggested that medium-dose CC supports bone integrity comparably to vitamin C a& may exert osteoprotective effects beyond direct reactive oxygen species (ROS) scavenging, offering a potentially safer alternative for bone health under oxidative stress. In this study compared the effects of CC extract & vitamin C on oxidative stress & bone health in a rat model of exercise-induced oxidative stress.

   • According to Shui G (2005)

     Excerpt High content of antioxidants contained in ulam raja could be partly responsible for its ability to reduce oxidative stress. Ulam raja (Cosmos caudatus) is used traditionally for improving blood circulation.

   • According to Noriham A (2015)

     Excerpt Therefore, this study investigated antioxidant activity of Cosmos caudatus leaves at three different maturity stages (young, mature & old leaves) extracted using two extraction solvents (water & 95% ethanol). Hence, it can be concluded that CC young leaves extracted using water had the most powerful antioxidant, suggesting their potential application as health-promoting functional ingredients or natural preservatives in food & pharmaceutical products,.

   • According to Mediani A (2013)

     Excerpt The aim of the study was to analyze the influence of oven thermal processing of Cosmos caudatus on the total polyphenolic content (TPC) & antioxidant capacity (DPPH) of two different solvent extracts (80% methanol, & 80% ethanol).

3. 3

   Dyslipidaemia: hypercholesterolaemia, hyperlipidaemia, hypertriglyceridaemia, atherosclerosis

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to ABDUL RAHMAN H (2017)

     Excerpt The present study aimed at investigating anti-obesity potential of ethanolic extract from Cosmos caudatus Kunth leaf (EECCL).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.