Crinum asiaticum (Lily of St Joseph) : medicinal properties in alcoholic extraction

Crinum asiaticum (Lily of St Joseph, Lys de St-Joseph) — family Amaryllidacées.

Scientific synonyms : Amaryllis carnosa Hook.f., Bulbine asiatica (L.) Gaertn., Crinum anomalum Herb., C bancanum Kurz, C bracteatum Willd., C declinatum Herb., C hornemannianum M.Roem..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 45 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ghane SG (2018)

     Excerpt Aqueous & methanolic leaf extracts of twelve Crinum genotypes were evaluated for their phytochemicals, antioxidants, in vitro anti-diabetic & acetyl cholinesterase (AChE) inhibitory activities. asiaticum form 2 whereas maximum total alkaloid content (TAC) (10.81 ± 0.22 mg CoE g−1 extract), total flavonoid content (TFC) (145.06 ± 3.95 mg CE g−1 extract) & TTC (436.55 ± 3.70 mg CE g−1 extract) content were recorded for C.

   • According to Indradevi S (2012)

     Excerpt The experimental rats were randomly divided into three groups: Group I: control; Group II: alloxan induced diabetic rats & Group III: alloxan induced diabetic rats were treated with ethanolic extract of Crinum asiaticum leaves (200mg/kg/bw). Diabetes mellitus was induced by alloxan in a single dose of 200mg/kg/bw.

   • According to Mishra A (2021)

     Excerpt In the present investigation the glucose lowering potential of the leaf extracts of Crinum asiaticum were prepared using cold maceration technique in solvents of varying polarity. Oral glucose tolerance test was performed & diabetes was induced using alloxan (150 mg/kg) in rats.

2. 2

   Inflammatory conditions: osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kongkwamaroen C (2021)

     Excerpt The objectives of this study were to investigate different treatments of C.A leaves prior to ethanolic extraction & to compare the extracts for their anti-inflammatory activity & chemical properties. Results showed that 95% ethanolic extract of hot air oven-dried leaves had the highest anti-inflammatory activity & total phenolic & lycorine contents.

   • According to Samud AS (1999)

     Excerpt In the present study, we examined the anti-inflammatory effects of this plant extract on carrageenan-induced hind paw oedema in mice. In an attempt to study the mechanism of action of its anti-inflammatory activity, the effects of CFME on BK- & histamine-induced contractions were investigated in isolated rat uterus & guinea-pig ileum preparations, respectively.

   • According to Mahomoodally MF (2021)

     Excerpt In ethnomedicine, it is employed to relieve anguish from a plethora of ailment conditions such as boils, contusions, earache, edema, fever, fractures, gastrointestinal complaints, hernia, mumps, rheumatism, tonsillitis, urinary difficulties & vomiting, amongst others. Extracts & compounds from CA have been evaluated for their antioxidant, analgesic, anti-inflammatory, anti-plasmodial, cytotoxicity, anti-cancer & antimicrobial properties.

   • According to Bin-Emran T (2012)

     Excerpt The present study was carried out to investigate the anti-inflammatory & antioxidant & properties of ethanol extract of Crinum asiaticum (Syn: Crinum amabile) leaf. These results indicate that Crinum asiaticum leaf extract have potent anti-inflammatory effect.

   • According to Rahman A (2013)

     Excerpt This study investigated the analgesic & anti-inflammatory effects of Crinum asiaticum (Amaryllidaceae) leaf ethanolic extract. Anti-inflammatory effect was conducted in carrageenan-induced paw edema model of albino rat.

3. 3

   Bacterial infection: Escherichia coli, Staphylococcus aureus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dūmā-Riris I (2018)

     Excerpt In addition, the antibacterial test showed that the widest inhibition of the leaves a&bulbs are 15.7 mm and 12.4 mm against Escherichia coli respectively & 12.3 mm & 11.5 mm against Staphylococcus aureus. The antioxidant, toxicity and antibacterial of the Crinum leaves & bulbs extracted with ethanol & treated by DPPH (2-2 diphenyl 1-1-picrylhydrazyl) method, Brine Shrimp Lethality Test (BSLT) method, & diffusion method respectively.

   • According to JI Yubin (2013)

     Excerpt -Kale S et al, Formulation & In-vitro Evaluation for Sun Protection Factor of Crinum asiaticum Linn flower (Family-Amaryllidaceae) Extract Sunscreen Creams Indian J of Pharmaceut Educ & Res, 2012; 46(2):112-9-Abstract: Crinum asiaticum flowers commonly known as white lily flowers were explored to find flavonoids, so, thin layer chromatography was performed & some of the flavonoids were identified as flavon (Apigenine ), flavonol (Quercetin), flavan-3-ols (Catechin), isoflavones (Daidzein). The basic structures of Crinum Asiaticum alkaloids are N-(3, 4-dioxo-benzyl)-4-O-phenylethylamine, pyrrole phenanthridine, 5,10b-ethanophenanthridine.

   • According to Goswami S (2020)

     Excerpt Crinum asiaticum is an evergreen bulbous perennial shrub of Amaryllidaceae family with ethnomedicinal importance & our earlier study described a comparative account antimicrobial & antioxidant property of the different solvent-mediated sequential extract fractions. Thus the present study supplements to our earlier report, that indicated the last aqueous extract fraction of C.A has potent antioxidant & antibacterial potentials as well as its prospective use in livestock maintenance, as it is least toxic & the ethyl acetate extract, the most toxic fraction identified here, is needed to explore for pharmaceutical importance.

   • According to Ilavenil S (2010)

     Excerpt Ilavenil S et al, EVALUATION OF ANTIBACTERIAL ACTIVITY & PHYTOCHEMICAL ANALYSIS OF Crinum asiaticum, Inter J of Current Res, 1: 035-040, 2010,.

   • According to Chairul (2010)

     Excerpt The antibacterial activity of ethanolic extract of leaves & bulbs of Crinum asiaticum was tested against Propionibacterium acnes, Staphylococcus aureus & Staphylococcus epidermidis, pathogenic bacteria that cause acne.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.