Crinum latifolium (Variegated lily) : medicinal properties in alcoholic extraction

Crinum latifolium (Variegated lily, Lis-panaché, Lys panaché) — family Amaryllidacée.

Scientific synonyms : Amaryllis littoralis Salisb. Crinum ornatum subvar. Acutior, Crinum ornatum var. latifolium (L.) Herb..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 3 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 48 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to CHANDANA JVS (2024)

     Excerpt The present study was done to investigate the In-Vitro antioxidant & antidiabetic activity of ethanolic extract of Crinum latifolium leaves. Overall, the present study results suggested that ethanolic extract of CL leaves has potential antioxidant & antidiabetic activities.

   • According to GOYAL A (2023)

     Excerpt Amaryllidaceae family member Crinum latifolium Linn. Additionally, the review delves into the numerous pharmacological activities associated with CL, such as antitumor, anti-inflammatory, antioxidant, & anti-diabetic activities.

   • According to Shukla PK (2018)

     Excerpt Pharmacognostical study along with the development of a quantitative HPTLC method for Crinum latifolium & evaluation of its traditional claims. In vitro antidiabetic potential of both the parts were assessed by starch iodine color assay & DNS method of alpha-amylase inhibition model.

   • According to Ahmad MH (2018)

     Excerpt Ahmad MH et al, Preliminary phytochemical screening & antidiabetic activity of extracts of leaves of Crinum latifolium Linn.

   • According to DATTATRAY JA (2026)

     Excerpt Crinum latifolium Linn., a medicinally important plant belonging to the family Amaryllidaceae, is widely distributed across tropical, subtropical, & warm temperate regions of the world. The plant has demonstrated a variety of pharmacological activities, including antitumor, anti-inflammatory, antioxidant, analgesic, antimicrobial, hepatoprotective, & antidiabetic effects.

2. 2

   Oxidative stress

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to CHANDANA JVS (2024)

     Excerpt The present study was done to investigate the In-Vitro antioxidant & antidiabetic activity of ethanolic extract of Crinum latifolium leaves. Overall, the present study results suggested that ethanolic extract of CL leaves has potential antioxidant & antidiabetic activities.

   • According to Chen MX (2018)

     Excerpt Four novel & potently bioactive Amaryllidaceae alkaloids, 4,8-dimethoxy-cripowellin C (1), 4,8-dimethoxy-cripowellin D (2), 9-methoxy-cripowellin B (3), and 4-methoxy-8-hydroxy-cripowellin B (4), together with one known alkaloid, cripowellin C (5) were isolated from the 95% EtOH extract of the bulbs of Crinum latifolium. Alkaloids 3 & 4 displayed the significant antimicrobial activity with IC50 values <0.50 mM & antioxidant activity in the ABTS·+ & DPPH test.

   • According to GOYAL A (2023)

     Excerpt Amaryllidaceae family member Crinum latifolium Linn. Additionally, the review delves into the numerous pharmacological activities associated with CL, such as antitumor, anti-inflammatory, antioxidant, & anti-diabetic activities.

   • According to Gasca-Silva CA (2022)

     Excerpt Crinum latifolium L. Several phytochemical & biological studies on this species have been conducted, and pharmacological studies have revealed its promising anti-inflammatory, antioxidant, & anticancer properties using different in vitro & in vivo models.

   • According to AZIZ A (2014)

     Excerpt Crinum latifolium is a widely used plant in Asian folk & traditional medicine.

3. 3

   Benign prostatic hyperplasia

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Thongphichai W (2022)

     Excerpt (Amaryllidaceae) has been used in Southeast Asian traditional medicine to alleviate the symptoms of benign prostatic hyperplasia (BPH). Crinum latifolium L.

   • According to Jenny M (2011)

     Excerpt Additionally, we measured also dose-dependent inhibitory effects of this aqueous CL extract on cell proliferation of highly metastatic human prostate carcinoma PC3 cells (IC (50) = 4.5 ± 0.8 mg/ml), androgen-sensitive prostate adenocarcinoma LNCaP cells (IC(50) =2.3 ± 0.1 mg/ml), & benign prostate hyperplasia BPH-1 cells (IC(50) = 2.1 ± 0.04 mg/ml). We conclude that both effects, inhibition of tumor cell growth & recovery of immune functions, are important for the antitumor properties of Crinum latifolium.

   • According to Wondrak JA (2011)

     Excerpt Additionally, we measured also dose-dependent inhibitory effects of this aqueous CL extract on cell proliferation of highly metastatic human prostate carcinoma PC3 cells (IC50 = 4.5 ± 0.8 mg/ml), androgen-sensitive prostate adenocarcinoma LNCaP cells (IC50 =2.3 ± 0.1 mg/ml), & benign prostate hyperplasia BPH-1 cells (IC50 = 2.1 ± 0.04 mg/ml). The Indian species Crinum latifolium (L.) was traditionally used to treat rheumatism, fistula, tumors, earaches, rubefacient, tubercle & whitlow.

   • According to Author (2001)

     Excerpt Levin S: Traditional Vietnamese herb Crinum latifolium shows promise for prostate & ovarian health.

   • According to Author (2013)

     Excerpt Crinum latifolium L. (CL) leaf extracts have been traditionally used in Vietnam & are now used all over the world for the treatment of prostate cancer.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.