Cryptostegia grandiflora (Purple Alamanda) : medicinal properties in alcoholic extraction

Cryptostegia grandiflora (Purple Alamanda, Alamanda pourpre) — family Apocynacées.

Scientific synonyms : C. grandiflora var. tulearensis Constantin & Gallaud.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 24 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of squamous cell carcinoma (epithelioma)

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to El Zalabani S (2003)

     Excerpt The alcohol extracts of the flowers, seeds & non-flowering branches of Cryptostegia grandiflora R.B. Cytotoxic activity was determined using Ehrlich ascites carcinoma (EAC) cell-line, in vitro.

   • According to DOSKOTCH W (1972)

     Excerpt An alcoholic extract of the aboveground parts of Cryptostegia grandiflora showed inhibitory activity against the KB cell culture & was fractionated through a series of partitions & column chromatography to yield five cardenolides: oleandrigenin, 16-propionylgitoxigenin-a new natural product, 16-anhy drogitoxigenin, gitoxigenin, & rhodexin B,.

   • According to Albuquerque TM (2009)

     Excerpt In this study pro-inflammatory activity in the latex of Cryptostegia grandiflora was investigated. Mast cell depletion provoked by 40/80 compound did not modify the course of inflammation triggered by CgLP, being similar to fMLP, which suggested that neutrophil migration was induced by direct mechanism mediated by macrophages.

2. 2

   Bacterial infection: Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rivera A (2015)

     Excerpt Br., against ATCC strains of Staphylococcus aureus (25923), Klebsiella pneumoniae (13883) & Pseudomonas aeruginosa (27853). In this work we evaluated the antibacterial activity of the total ethanolic extracts obtained from the calyces of Physalis angulata L.

   • According to El Zalabani S (2003)

     Excerpt The antifungal activity is for the first time reported, & exceeds in most cases the antibacterial effect. The alcohol extracts of the flowers, seeds & non-flowering branches of Cryptostegia grandiflora R.B.

   • According to Mukherjee PK (1999)

     Excerpt leaves were investigated for their antibacterial potential against Pseudomonus cepacia NCIM-2106, Bacillus megatorium NCIM-2087, Staphylococcus aureus NCIM-2492, Escherichia coli NCIM-2345, Bacillus subtilis NCIM-2349 & Bacillus coagulans NCIM 2323. Different extracts of Cryptostegia grandiflora (Roxb) Rbr.

   • According to Singh B (2011)

     Excerpt Singh B et al: Estimation of phytoconstituents from Cryptostegia grandiflora (Roxb.) R.

   • According to El Saed Momeana (2011)

     Excerpt El Saed Momeana et al, Cryptostegia Grandiflora Affecting Compatibility of Biomphalaria Alexandrina & Biomphalaria Galabrata to Infection with Schistosoma Mansoni with Emphasis on Some Hematological Effects Australian J of Basic & Applied Sci, 5(12): 3357-3365, 2011 ISSN 1991-8178,.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Albuquerque TM (2009)

     Excerpt In this study pro-inflammatory activity in the latex of Cryptostegia grandiflora was investigated. CgLP-induced inflammation was observed in peritonitis, paw edema & air push models.

   • According to Castro JP (2014)

     Excerpt (Apocynaceae) leaves are widely used in folk Caribbean Colombian medicine for their anti-inflammatory effects, there are no studies that support this traditional use. Conclusions: Our results demonstrated for the first time the anti-inflammatory activity of CG leaves, supporting its traditional use.

   • According to de Freitas DTC (2010)

     Excerpt In this study, proteins extracted from laticifer cells of three plants were examined by electrophoresis, mass spectrometry (MALDI-TOF) & characterized in respect of proteolytic, chitinolytic & anti-oxidative activities by means of zymography & colorimetric assays. grandiflora latices, & to a lesser extent ascorbate peroxidase (E.C.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.