Cydonia oblonga (Quince) : medicinal properties in alcoholic extraction

Cydonia oblonga (Quince, Coing) — family Rosacées.

Scientific synonyms : Crataegus serotina Salisb., Cydonia communis Loisel., C. europaea Savi, C. lobata Bosc, C lusitanica Mill., C maliformis Mill., C oblonga subsp. Maliformis (Mill.) Thell., C oblonga subsp. Pyriformis (Medik.) Thell., C pyriformis Medik., C sumboshia Buch. Ham., C sylvestris Risso, C tomentosa Koch, C umbato M. Roem., C vulgaris Delarbre, C vulgaris Pers., Pyrus cydonia L.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 70 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of colorectal, liver and breast cancer

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Dalkilic LK (2024)

     Excerpt Dalkilic LK et al, Investigation of Antioxidant, Antimicrobial & Cytotoxic Activity of Cydonia oblonga Leaf on Breast Cancer (MCF-7) & Liver Cancer (HepG2) Cell Lines Turkish J of Sci & technol, 19:1, 2024-.

   • According to Shimizu S (1977)

     Excerpt -farnesene, a sesquiterpene hydrocarbon, and ethyl esters of saturated & unsaturated fatty acids; hexanoic, octanoic, dodecanoic, decanoic, deca-dienoic, dodecanoic, tetra-decanoic & tetra-deca-dienoic acids. Chromatographic & spectral studies of the major volatile constituents of Japanese quince fruit oil are reported.

   • According to Mirmohammadlu M (2015)

     Excerpt Mirmohammadlu M et al, hypolipidemic, Hepatoprotective & Renoprotective Effects of Cydonia Oblonga Mill fruit in Streptozotocin-Induced Diabetic Rats.

   • According to Abliz A (2014)

     Excerpt Results: COM dose-dependently reduced TC, TG, LDL-C & MDA, inhibited the activity of ALT, AST & LPS, increased HDL-C content, increased the activity of SOD, GSH-PX, LPL & HL, & reduced liver steatosis in hyperlipidaemia rats, which was significant at medium & high doses. The antioxidant capacity of glutathione peroxidase (GSH-PX), superoxide dismutase (SOD), malondialdehyde (MDA) was measured in liver samples, along with lipoprotein lipase (LPL), & hepatic lipase (HL).

   • According to Carvalho M (2010)

     Excerpt The present study reports the phenolic profile & antiproliferative properties of quince (Cydonia oblonga Miller) leaf & fruit (pulp, peel, & seed) against human kidney & colon cancer cells. Concerning the fruit, seed extracts exhibited no effect on colon cancer cell growth, whereas strong antiproliferative efficiency against renal cancer cells was observed for the highest concentration assayed (500 μg/mL).

2. 2

   Type II diabetes mellitus

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to DANG T (2016)

     Excerpt Cydonia oblonga Miller (Rosaceae) is used in traditional Uyghur medicine & is proved to have antioxidant and antihypertensive properties, but the anti-diabetic activity of COl seeds extracts (CSE) is not yet explored. Diabetes mellitus is one of the most common metabolic syndromes characterized by hyperglycemia.

   • According to Chi B (2022)

     Excerpt The aim of this study was to investigate the in vitro antidiabetic activity & anti-diabetic mechanism of CO COMF). Cydonia Oblonga Mill.

   • According to Mirmohammadlu M (2015)

     Excerpt Mirmohammadlu M et al, hypolipidemic, Hepatoprotective & Renoprotective Effects of Cydonia Oblonga Mill fruit in Streptozotocin-Induced Diabetic Rats.

   • According to Abed S (2022)

     Excerpt The Cydonia oblonga bark extraction was fractionated through HPLC & seven purified fractions labeled as F1, F2, F3, F4, F5, F6, and F7 were obtained. Cydonia oblonga is a medicinal plant that is used to treat a number of health complications in traditional medication systems.

3. 3

   Bacterial infection: Escherichia aerogenes, E. coli, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumoniae, Moraxella

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to AL-KHAZRATI SKH (2013)

     Excerpt The antibacterial activity of the seeds extract was assayed against Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumonia, Escherichia coli & Moraxella using the agar well diffusion method. The extract exhibited antibacterial activity; S aureus was the most susceptible to the plant seeds extract while Escherichia coli & Moraxella were the most resistant.

   • According to Sabir S (2024)

     Excerpt The methanolic & aqueous extracts of quince fruit showed the highest zone of inhibition 17.4 ± 0.15 & 17.53 ± 0.26 mm against Pseudomonas aeruginosa & Staphylococcus aureus, respectively, which showed their efficacy as a potent antimicrobial. Quince (Cydonia oblonga Mill.) is a native plant of Central Asia having a long history of ethnobotanical & medicinal use.

   • According to Diler Demirbuker kavak (2017)

     Excerpt The aim of this present study was to investigate the effects of solvent concentration, extraction temperature and time on total phenolic content and antioxidant activity of the Quince, Cydonia oblonga Mill. Determination of the optimal conditions for the extraction of Quince leaves (40% ethanol-water mixture at 70ºC for 30 minutes) is important for a cost saving extraction, and health-promoting functions of Quince leaves as a food ingredient with both antioxidant and antimicrobial potential.

   • According to Dalkilic LK (2024)

     Excerpt Dalkilic LK et al, Investigation of Antioxidant, Antimicrobial & Cytotoxic Activity of Cydonia oblonga Leaf on Breast Cancer (MCF-7) & Liver Cancer (HepG2) Cell Lines Turkish J of Sci & technol, 19:1, 2024-.

   • According to Fattouch S (2007)

     Excerpt Fattouch S et al, antimicrobial activity of Tunisian Quince (Cydonia oblonga Miller) pulp & peel polyphenolic extracts.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.