Dichrostachys cinerea (Akasia-Sen-Domeng) : medicinal properties in alcoholic extraction

Dichrostachys cinerea (Akasia-Sen-Domeng, Acacia of Santo Domingo, Acacia-de-St-Domingue) — family Mimosacées.

Scientific synonyms : Ailliea glomerata (Forssk.) J.F. Macbr., Dichrostachys glomerata (Forssk) Chiov, D platycarpa Welw, D. nutans (Pres.) Benth, Mimosa cinerea L, M glomerata Forssk, M nutans Per..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 29 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of carcinoma resistant to antineoplastic drugs: colorectal, breast, liver, leukaemia and glioblastoma

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Suresh Babu P (2011)

     Excerpt Suresh Babu P et al, Evaluation of acute toxicity & hepatoprotective activity of the methanolic extract of Dichrostachys cinerea (Wight & Arn.) leaves, , Pharmacognosy Res, 2011, 3 (1): 40-3.

   • According to Adikay S (2009)

     Excerpt The alcoholic extract of roots of Dichrostachys cinerea Wight & Arn. cinerea showed protective effect against cisplatin-induced nephrotoxicity which may probably be mediated by its antioxidant property.

   • According to Mbaveng TA (2019)

     Excerpt D cinerea is an interesting cytotoxic plant & deserves more studies leading to new antineoplastic agents to fight cancer & mostly leukemia. The recorded IC 50 values varied from 7.65 μ M (towards multidrug-resistant CEM-ADR5000 leukemia cells) to 44.17 μ M (against HepG2 hepatocarcinoma cells) for 1, 18.90 μ M (CCRF-CEM leukemia cells) to 88.86 μ M (against HCT116p53 +/+ colon adenocarcinoma cells) for 4, & 0.02 μ M (against CCRF-CEM cells) to 122.96 μ M (against CEM/ADR5000 cells) for doxorubicin.

   • According to Hassan HS (2012)

     Excerpt These plants were the whole plant of Schwenckia americana Linn (WSA), the rhizomes of Asparagus africanus Lam (RAA), the leaves of Dichrostachys cinerea Linn (LDC), the stem bark of Ficus iteophylla Miq (BFI) and the leaves of Indigofera pulchra Willd (LIP). Crude saponin extracts of five medicinal plants used in the treatment of inflammatory diseases like Rheumatoid arthritis, gout and Haemorrhoids were screened for anti-inflammatory activity using carrageenan-induced rat paw oedema test.

   • According to Susithra E (2018)

     Excerpt The results of antioxidant activity act as a prelude for anti-inflammatory study and these are attributed to the presence of phytoconstituents tested in our extracts. Anti-inflammatory screening indicates that stem bark, leaf, and root were effective in acute model, whereas stem bark is ineffective in chronic model.

2. 2

   Pain

   Plant part used: Root.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Susithra E (2018)

     Excerpt The results of antioxidant activity act as a prelude for anti-inflammatory study and these are attributed to the presence of phytoconstituents tested in our extracts. Anti-inflammatory screening indicates that stem bark, leaf, and root were effective in acute model, whereas stem bark is ineffective in chronic model.

   • According to Hassan HS (2012)

     Excerpt Crude saponin extracts of five medicinal plants used in the treatment of inflammatory diseases like Rheumatoid arthritis, gout and Haemorrhoids were screened for anti-inflammatory activity using carrageenan-induced rat paw oedema test. The anti-inflammatory study of the extracts showed statistically significant (P<0.05) decreases in the rat paw-oedema as compared to the control.

   • According to Atsang GK (2022)

     Excerpt This study aimed to characterize the polyphenol-rich DC fruit extracts and investigate the analgesic, anti-inflammatory, and antioxidant effects in a rat inflammation model induced by complete Freund’s adjuvant (CFA). These results showed potential anti-inflammatory, analgesic, and antioxidative properties and revealed the necessity of using a standardized polyphenolic DC extract to avoid result variability.

   • According to Reine Rr (2014)

     Excerpt Reine Rr et al, Dichrostachys Cinerea, (L.) Wight Et Arn (Mimosaceae), Potential on antiinflammatory Activity & Protection, in Anaphylactic in Conscious Guinea Pig, Res-Gate, 2014.

   • According to Vijayalakshmi M (2013)

     Excerpt The leaves of D cinerea are used as laxative, diuretic, pain killer. cinerea leaves were performed by standard chemical tests, thin layer chromatography (TLC) by using various solvent systems, and by high performance liquid chromatography (HPTLC).

3. 3

   Rheumatoid arthritis

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Atsang GK (2022)

     Excerpt (DC) is widely used in traditional medicine against several inflammatory diseases, especially rheumatoid arthritis, because of its antioxidant and anti-inflammatory effects. This study aimed to characterize the polyphenol-rich DC fruit extracts and investigate the analgesic, anti-inflammatory, and antioxidant effects in a rat inflammation model induced by complete Freund’s adjuvant (CFA).

   • According to Hassan HS (2012)

     Excerpt Crude saponin extracts of five medicinal plants used in the treatment of inflammatory diseases like Rheumatoid arthritis, gout and Haemorrhoids were screened for anti-inflammatory activity using carrageenan-induced rat paw oedema test. The anti-inflammatory study of the extracts showed statistically significant (P<0.05) decreases in the rat paw-oedema as compared to the control.

   • According to Susithra E (2018)

     Excerpt The results of antioxidant activity act as a prelude for anti-inflammatory study and these are attributed to the presence of phytoconstituents tested in our extracts. Anti-inflammatory screening indicates that stem bark, leaf, and root were effective in acute model, whereas stem bark is ineffective in chronic model.

   • According to Reine Rr (2014)

     Excerpt Reine Rr et al, Dichrostachys Cinerea, (L.) Wight Et Arn (Mimosaceae), Potential on antiinflammatory Activity & Protection, in Anaphylactic in Conscious Guinea Pig, Res-Gate, 2014.

   • According to Vijayalakshmi M (2013)

     Excerpt cinerea leaves were performed by standard chemical tests, thin layer chromatography (TLC) by using various solvent systems, and by high performance liquid chromatography (HPTLC). cinerea leaves showed the presence of Carbohydrates, proteins, Glycosides, Saponins, Tannins, Aminoacids alpha-terpenoids.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.