Dioscorea alata (Yanm Sen-marten) : medicinal properties in alcoholic extraction

Dioscorea alata (Yanm Sen-marten, Yanm Blan, Anba-bon, St Martin yam, White yam, En-bas-est-bon, Igname de St -Martin, Igname Blanc) — family Dioscoréacées.

Scientific synonyms : Dioscorea alata var globosa-®-P, D alata var purpurea-®-AP, D atropurpurea-R, D colocasiifolia-P, D eburina-L, D ebúrnea-L, D globos-R, D javanica hort ex Q, D purpurea R, D rubella-R, D sapinii DW, D vulgaris-M, Elephantodon eburneus-S, Polynome alata-S.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 72 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Maithili V (2011)

     Excerpt To evaluate the antidiabetic activity of ethanolic extract of Dioscorea alata in glucose loaded & alloxan induced diabetic rats. Diabetes mellitus was induced by alloxan monohydrate (120 mg/kg, i.p.) in physiological saline after overnight fasting for 18 hours.

   • According to Guo X (2015)

     Excerpt Peel extract exerted better bioactivity than flesh extract, which indicated that purple yam peel, a kind of kitchen waste that is always overlooked, might serve as a promising therapeutic natural product for the prevention of diabetes or other advanced glycation end products-related diseases.

   • According to Rosida (2018)

     Excerpt The findings of this research can facilitate the development of functional food for the healthiness of human, & for diabetic & hypercholesterolemia patient. It can be concluded that modified white water yam was proved to pose hypocholesterolemic & hypoglycemic effects & could be developed as functional food.

   • According to Dey P (2014)

     Excerpt The underground tuber of Dioscorea alata is a palatable food and is also claimed to have therapeutic effects. Various groups of researchers demonstrated different activities of this tuber such as antioxidant, hepatoprotective, anti-ulcer & anti-diabetic activities.

   • According to Adeloye JB (2021)

     Excerpt Hence, the study provides a rationale that dough meal from unripe plantain; water yam & bitter leaf have the potential to be used as functional foods to alleviate postprandial hyperglycemia. In all age groups globally, diabetes is a metabolic disease that is associated with oxidative stress caused by reactive free radicals in the human system.

2. 2

   Oxidative stress

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hsu CK (2011)

     Excerpt The effects of water & 50% ethanolic extracts from Dioscorea alata peel on the oxidative status of tert-butyl hydroperoxide (t-BHP)-treated mouse Hepa 1–6 & FL83B liver cell lines were investigated. GPx activity might play an important role in the protective effect associated with t-BHP-induced oxidative stress.

   • According to Chen CT (2017)

     Excerpt The present study was designed to explore whether yam could protect the heart from doxorubicin (DOX)-induced oxidative stress leading to cardiotoxicity in vivo. japonica Thunb., water extracts of Dioscorea alata, ethanol extracts of D.

   • According to Chang SJ (2004)

     Excerpt DA feeding exhibited its antioxidative effects in HHcy including alleviating PA, lipid peroxidation, & oxidative stress, but did not induce activity of antioxidant enzymes which had already adaptively increased by HHcy. Plasma malondialdehyde levels, an indicator of lipid peroxidation, & hepatic reactive oxygen species, an indicator of oxidative stress, of HHcy with DA feeding were significantly lower than that without DA feeding.

   • According to Adeloye JB (2021)

     Excerpt In all age groups globally, diabetes is a metabolic disease that is associated with oxidative stress caused by reactive free radicals in the human system. Hence, this study aimed to determine the antioxidant, α-amylase & α-glucosidase activities, glycemic index, blood glucose concentration a sensory attributes of dough meals developed from flour blends of unripe plantain, water yam & bitter leaf.

   • According to Das A (2014)

     Excerpt The purpose of this study was to delineate the differential antioxidant, ROS scavenging & iron chelation activities of the 70% methanolic extract (DALM) & aqueous extract (DALA) of Dioscorea alata L. These results confirm the possible role of the 70% methanolic extract as a promising free radical scavenger & as a potent antioxidant & anticancer source.

3. 3

   Doxorubicin-induced cardiomyopathy

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chen CT (2017)

     Excerpt The present study was designed to explore whether yam could protect the heart from doxorubicin (DOX)-induced oxidative stress leading to cardiotoxicity in vivo. japonica Thunb., water extracts of Dioscorea alata, ethanol extracts of D.

   • According to Wu WH (2005)

     Excerpt Methods: Twenty-four apparently healthy postmenopausal women were recruited to replace their staple food (rice for the most part) with 390 g of Dioscorea alata in 2 of 3 meals per day for 30 days & 22 completed the study. These effects might reduce the risk of breast cancer & cardiovascular diseases in postmenopausal women.

   • According to Chen T (2017)

     Excerpt The purple yam, Dioscorea alata L., is an important source of starch, vitamins & polyphenols.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.