Dioscorea esculenta (Soft couscous) : medicinal properties in alcoholic extraction

Dioscorea esculenta (Soft couscous, Impossible yam, Kouskoush dous, Yanm pa posib, Couscouche doux, Igname pas-possible) — family Dioscoréacées.

Scientific synonyms : Dioscorea esculenta (Lour.) Burkill, D fasciculata Roxb., D papillaris Blanco, D papuana Warb., D tiliifolia Kunth, D tugui Blanco, Onchorhiza esculentus (Lour.) Pers. Oncus esculentus Lour..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 48 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for breast cancer

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Haryoto (2019)

     Excerpt This study is conducted to know the anti-cancer activity on ethanol extract, nonpolar, semi polar & polar fractions of lesser yam (Dioscorea esculent L.) herbs. One of the diseases that have a high contribution to the death of women in the world is breast cancer.

   • According to Soetoro DF (2012)

     Excerpt It has anticancer activities & anti-proliferative effect against T47D breast cancer cell line. The present study aims to investigate the anti- proliferative effect of ethanolic extract of gembili against T47D breast cancer line.

   • According to Fatmawaty D (n.d.)

     Excerpt In our present study, the combination of Doxorubicin (Dox) & ethanol extract of Dioscorea esculenta tuber was found to have a synergistic effect on T47D human breast cancer cell line. In this study, we investigated the apoptotic effect of the combination on T47D human breast cancer cells & normal fibroblasts cell line & its effects on the expression of Caspase-3 & cleaved poly (ADP-Ribose) Polymerase-1 (cPARP-1) protein.

   • According to Silalahi M (2022)

     Excerpt The bioactivity of DE is anti-inflammatory, anti-diabetic mellitus, anti-microbial, antioxidant, anti-fertility & anti-cancer. Dioscorea esculenta (Dioscoreaceae) has been long used as an alternative food ingredient & traditional medicine.

   • According to Ervietasari N (2021)

     Excerpt DE tubers (Dioscorea esculenta) are included in the local tubers which contain 14.629% inulin content. Inulin can reduce the risk of colon cancer, normalize blood sugar levels & help with heart health & prevent colon cancer.

2. 2

   Bacterial infection: Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Begum AT (2013)

     Excerpt the present study was aimed to screen the antimicrobial activity of tuber mucilage from Dioscorea esculenta by in-vitro well diffusion assay method against five bacterial strains, viz, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus aureus, a Streptococcus pyogens. Te extracts showed antibacterial activity against E coli, P aeruginosa, & S aureus, while no activity was showed by the extract against K pneumoniae & S pyogens, whereas maximum inhibition concentration (MIC) was observed in 50 microg concentration of the extract against C coli?

   • According to Khasanah Y (2019)

     Excerpt Gembili (Dioscorea esculenta (Lour.) Burkill) is known as functional food that contains oligosaccharides. Potential of prebiotics was analysed using faecal samples from healthy volunteers in anaerobic condition at certain time interval (0, 24, & 48 hours) & bacterial growth (Bifidobacteria & Lactobacillus as probiotic bacteria, Bacteroides & Clostridium as patogen bacteria), prebiotic index were analysed.

3. 3

   Hypo-prebiotic: Bifidobacteria & Lactobacillus Case i

   Plant part used: Tuber.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Khasanah Y (2019)

     Excerpt Potential of prebiotics was analysed using faecal samples from healthy volunteers in anaerobic condition at certain time interval (0, 24, & 48 hours) & bacterial growth (Bifidobacteria & Lactobacillus as probiotic bacteria, Bacteroides & Clostridium as patogen bacteria), prebiotic index were analysed. Gembili (Dioscorea esculenta (Lour.) Burkill) is known as functional food that contains oligosaccharides.

   • According to Nur Wanda AN (2022)

     Excerpt plantarum B1765 in the production of FOS from lesser yam tuber inulin by looking at the total growth of lactic acid bacteria (LAB) and the degree of polymerization (DP) during a certain fermentation time. This study was able to produce a commercially acceptable fructooligosaccharides with a DP of 3,470, which could be used for industrial development of fermented lesser yam tuber fructooligosaccharides.

   • According to Andriani RD (2020)

     Excerpt This tuber has bioactive compounds such as dioscorin, diosgenin, inulin & water-soluble polysaccharides that function as immunomodulators, including those which prevents metabolic diseases such as hyperglycaemia. Probiotics contained in fermented milk are Lactobacillus acidophilus, Lactobacillus plantarum & Streptococcus thermophilus.

   • According to Serafica BCK (2015)

     Excerpt Serafica BCK et al, Isolasi oligosakarida dari tepung umbi gembili (Dioscorea esculanta (Lour.) Burkill) dan potensinya sebagai prebiotik, Skripsi, Fakultas Biol, Univ Gadjah Mada, Yogyakarta, 2015-.

   • According to Winarti S (2013)

     Excerpt genus spread over countries including Indonesia, some of them are D hispida (Gadung), Dioscorea esculenta (gembili), Dioscorea bulbifera (gembolo), Dioscorea alata (purple yam), D opposita (uwi Putih), D villosa (yellow yam), & D altissima. The aim of this research is to evaluate the physio-chemical characteristics of yam tuber flour & prebiotic dodol made from yam tuber.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.