Dissotis rotundifolia (Lyenn-violèt-savann) : medicinal properties in alcoholic extraction

Dissotis rotundifolia (Lyenn-violèt-savann, purple savannah vine, liane violette à savane) — family Melastomacées.

Scientific synonyms : Dissotis deistelii Gilg ex Engl., D plumosa (D.Don) Hook.f., D prostrata (Thonn.) Hook.f., Heterocentron elegans auct. non Kuntze, Heterotis plumosa (D.Don) Benth., Melastoma plumosum D.Don, M prostratum Engl. Osbeckia rotundifolia Sm..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 33 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Abere TA (2010)

     Excerpt Inhibitory activity against clinical strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus & Salmonella typhi were compared with Gentamycin. The leaves of Dissotis rotundifolia are used ethnomedically across Africa without scientific basis or safety concerns.

   • According to Usanga VU (2023)

     Excerpt Antimicrobial test was assessed by agar diffusion at various concentrations against five clinical isolates namely; Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Citrobacter freundii & Candida species. Direct leaf extracts of Dissotis rotundifolia are commonly used in rural settings including Abakaliki, Ebonyi State, Nigeria as traditional medicine for the treatment of eye injury & related diseases with limited information on the scientific basis of the microbiological quality/safety of the extract.

   • According to VU U (2023)

     Excerpt Antimicrobial test was assessed by agar diffusion at various concentrations against five clinical isolates namely; Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Citrobacter freundii & Candida species. Direct leaf extracts of Dissotis rotundifolia are commonly used in rural settings including Abakaliki, Ebonyi State, Nigeria as traditional medicine for the treatment of eye injury & related diseases with limited information on the scientific basis of the microbiological quality/safety of the extract.

   • According to Soyinka JO (2008)

     Excerpt The partition & chromatographic fractions & isolates showed varied antimicrobial activities against Escherichia coli (NCTC 10418), Staphylococcus aureus (NCTC 6571), Pseudomonas aeruginosa (ATCC 10145), Bacillus subtilis (NCTC 8236) & Candida pseudotropicalis (NCYC 6), the organisms used, justifying their folkloric uses. Activity directed phytochemical investigation of the leaves of Dissotis erecta and Dissotis rotundifolia for antimicrobial & antioxidant properties using agar-diffusion & TLC bioautographic assays, & 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging test led to isolation of kaempferol (1) & kaempferol-3-O-β-D-glucopyranose (2) from D.

   • According to Dougnon VT (2017)

     Excerpt From the evaluation of the antibacterial activity, it is noted that six different strains showed a sensitivity towards the extracts (aqueous & ethanolic extract) of E hirta; three different strains for C aurantifolia & in the case of extracts of HR only two strains (Salmonella cholereasius & Klebsiella oxytoca) are not sensitive to any extract. This study aims to evaluate the antibacterial, antioxidant & cytotoxic properties of the aqueous & ethanolic extracts of the plants of Euphorbia hirta, Citrus aurantifolia & Heterotis rotundifolia; used in Benin in the traditional treatment of many diseases including infectious diseases & diarrhea.

2. 2

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Roko GO (2020)

     Excerpt Results: After injection of formalin to animals, inflammatory reaction was almost immediate with appearance of classic signs of acute local inflammation (Redness, pain, heat & edema) at the five experimental groups. The aim of this study is to evaluate the anti-inflammatory, analgesic & antipyretic properties of ethanolic extracts of these plants.

   • According to Kofi Yeboah O (2021)

     Excerpt Dissotis rotundifolia (Sm.) Triana has been used locally in the treatment of inflammatory conditions such as painful swellings & conjunctivitis. The leaf extract of DR showed significant amelioration of acetic acid- induced ulcerative colitis which may be attributable to its anti-inflammatory effect.

   • According to Usanga VU (2023)

     Excerpt Direct leaf extracts of Dissotis rotundifolia are commonly used in rural settings including Abakaliki, Ebonyi State, Nigeria as traditional medicine for the treatment of eye injury & related diseases with limited information on the scientific basis of the microbiological quality/safety of the extract. Conclusions: The findings of this study are supportive of the use of DR extract in the treatment of bacterial-related ocular diseases & inflammation,.

   • According to VU U (2023)

     Excerpt Direct leaf extracts of Dissotis rotundifolia are commonly used in rural settings including Abakaliki, Ebonyi State, Nigeria as traditional medicine for the treatment of eye injury & related diseases with limited information on the scientific basis of the microbiological quality/safety of the extract. Conclusions: The findings of this study are supportive of the use of DR extract in the treatment of bacterial-related ocular diseases & inflammation.

   • According to Adinortey MB (2020)

     Excerpt The drive for carrying out this research was to obtain data on the possible ameliorative effect of the whole plant extract of Dissotis rotundifolia (DRE) in gastric ulcerations induced by ethanol in Sprague Dawley (SD) rats. Dissotis rotundifolia is a plant in the family Melastomataceae.

3. 3

   Diarrhoea

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Abere TA (2010)

     Excerpt The leaves of Dissotis rotundifolia are used ethnomedically across Africa without scientific basis or safety concerns. In the castor oil induced diarrhoea test, all the doses showed anti-spasmodic effects.

   • According to Dougnon VT (2017)

     Excerpt This study aims to evaluate the antibacterial, antioxidant & cytotoxic properties of the aqueous & ethanolic extracts of the plants of Euphorbia hirta, Citrus aurantifolia & Heterotis rotundifolia; used in Benin in the traditional treatment of many diseases including infectious diseases & diarrhea.

   • According to Roko GO (2020)

     Excerpt The aim of this study is to evaluate the anti-inflammatory, analgesic & antipyretic properties of ethanolic extracts of these plants. Euphorbia hirta (whole plant), Citrus aurantifolia (leaf) & Heterotis rotundifolia (whole plant) are commonly used in Benin in the treatment of infectious diseases.

   • According to Kofi Yeboah O (2021)

     Excerpt Dissotis rotundifolia (Sm.) Triana has been used locally in the treatment of inflammatory conditions such as painful swellings & conjunctivitis. This study aimed at investigating the effect of Dissotis rotundifolia in acetic acid-induced ulcerative colitis.

   • According to Adinortey MB (2018)

     Excerpt This TTC dye method was further used in an antimicrobial susceptibility assay involving Dissotis rotundifolia extract (DRE).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.