Dunaliella salina (Red algae) : medicinal properties in alcoholic extraction

Dunaliella salina (Red algae, Algue rouge) — family Dunalielliacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 96 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to El-Baz FK (2016)

     Excerpt The aim of the current research is to study the effect of Dunaliella salina ethanolic extract on renal function & inflammatory cytokines in streptozotocin (STZ)-induced diabetic rats. Administration of DS ethanolic extract to diabetic rats demonstrated significant decrease in blood urea, creatinine, TNF-α & IL-1β levels.

   • According to El-Baz FK (2016)

     Excerpt The aim of the present investigation is to study the protective effect of the Dunaliella salina extract against streptozotocin (STZ)- induced type 2 diabetes mellitus (T2DM) in male rats. The biological effect of DS could be attributed to its high level of 9-cis - carotene which protect cells from the oxidative stress, hence, treatment of diabetic rats with DS extract declared therapeutic potential in hyperglycemia dominance which need further clinical trial for usage as nutraceutical product, in diabetic regimen,.

   • According to Ruperez FJ (n.d.)

     Excerpt Ruperez FJ et al, Dunaliella salina extract effect on diabetic rats:.

2. 2

   Cancer: adjuvant treatment for breast cancer (triple-negative)

   Plant part used: Whole plant. Mentioned synergistic association: Taxol.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Elleuch F (2020)

     Excerpt The biological activity assessment was performed on the Triple Negative Breast Cancer (TNBC) using 4T1 murine cells as a model. These results suggest a potential anticancer activity of Tunisian Dunaliella sp.

   • According to Ahmad H (2017)

     Excerpt The aim of this study: is to analyze the anti-cancer effects of extract of DS & to examine its effect on the level of cytotoxity of the medicine of Taxol, [&] on the extracted line cell of 4T1 of breast tumor of the Wistar rat (BALB/c). Dunaliella Salina micro alga is of great importance in this respect since it produces some materials with antioxidant quality.

   • According to Olmos J (2015)

     Excerpt In this work, effects of synthetic & natural β-carotene from DS were evaluated on MDA-MB-231 breast cancer cells, & even when apoptosis induction results were obtained with both sources, natural β-carotene generates considerable higher cell rates mortality,. Dunaliella salina is genus most important species for β-carotene production.

   • According to Emtyazjoo M (2012)

     Excerpt The scope of this study was survey of anticancer effect of the ethanol extract of Dunaliella salina algae under stress(EDSS) & normal (EDSN) conditions on death rate of skin carcinoma cell line A431 by MTT [3-(4,5-dimethylthiazol-2-y1)-2,5-diphenyltetrazolium bromide] method in vitro. Dunaliella salina, a green microalga, has been consumed as food & medicine for a long time.

   • According to Moghaddasi Z (2011)

     Excerpt Dunaliella salina is one of the micro algae in marine ecosystems containing beta-carotene, retinal, apocarotenoides, ketones, aldehydes & epoxides which enable it to absorb free radicals & produce singlet oxygen. The main goal of this research was to study the killing effects of the ethanol extract from the mentioned alga against Squamous cell carcinoma in vitro through using tetrazolium salt under in vitro conditions.

3. 3

   Bacterial infection: Escherichia coli, Staphylococcus aureus

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Herrero M (2006)

     Excerpt In the present work, the antimicrobial activity of different pressurized liquid extracts obtained from Dunaliella salina microalga was tested against several microorganisms of importance for the food industry (Escherichia coli, Staphylococcus aureus, Candida albicans, & Aspergillus niger). Because the main antimicrobial activity of the extracts was against bacteria, the extracts can be considered to be specifically antibacterial.

   • According to Herrero M (2006)

     Excerpt In the present work, the antimicrobial activity of different pressurized liquid extracts obtained from Dunaliella salina microalga was tested against several microorganisms of importance for the food industry (Escherichia coli, Staphylococcus aureus, Candida albicans, & Aspergillus niger). Results showed that the best antimicrobial activity was obtained for each solvent at the highest extraction temperature,.

   • According to Cakmak YS (2014)

     Excerpt The current study examines the antimicrobial and antioxidant properties of different extracts of the microalga Dunaliella salina Teodoresco (Dunaliellaceae), their fatty acid composition & the antimicrobial activity of the oil. Antimicrobial & antioxidant activities were evaluated by obtaining extracts of D.S in n-hexane, dichloromethane, ethanol, & methanol.

   • According to Mendiola J.A (2008)

     Excerpt The objective of this research was to evaluate the antimicrobial activity of carbon dioxide extracts of the unicellular biflagellated green alga Dunaliella salina against Escherichia coli, Staphylococcus aureus, Candida albicans, & Aspergillus niger. Under these conditions, the presence of an indolic derivative that had never been reported in DS was detected in the extract, together with polyunsaturated fatty acids & compounds related to carotene metabolism, such as β-ionone & neophytadiene, with known antimicrobial activity,.

   • According to Ambrico A. (2020)

     Excerpt The antibacterial activity of Dunaliella salina microalgae extracts were investigated in vitro & in vivo.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.