Durio zibethinus (Durian) : medicinal properties in alcoholic extraction

Durio zibethinus (Durian) — family Bombacacées.

Scientific synonyms : Durio acuminatissima Merr., D zibethinus L.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 127 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for hepatocellular carcinoma

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Saminathan V (2020)

     Excerpt It shows durian fruit extract to have an excellent anti-proliferative & anticancer activities against Chang liver cell lines. Durio zibethinus Murr is a seasonal tropical fruit of Southeast Asia.

   • According to Berry SK (1980)

     Excerpt Durian (Durio zibethinus, Murr.).

   • According to Pratiwi PD (2023)

     Excerpt This study was determined the hepatoprotector activity & effective dose of ethanol extract of durian (Durio zibethinus Murr.) leave on mice. Durian (Durio zibethinus Murr.) have been studied & reported has antioxidant activity & its potential as hepatoprotector.

   • According to Khonkarn R (2010)

     Excerpt We concluded that the EA fraction of rambutan peel is a promising resource for potential novel antioxidant agents whereas the hexane fraction of coconut peel may contain novel anticancer compounds.

   • According to Abdul Rahman MS (2023)

     Excerpt zibethinus fruits exhibited its anticancer effect on HL-60 cells by inducing DNA damage and apoptosis. Durian (Durio zibethinus L.) grows widely in Southeast Asia.

2. 2

   Type II diabetes mellitus

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Azura FH (2013)

     Excerpt Durian bark (Durio zibethinus) was reported to have beneficial fitonutrients potentially functioning as antihyperglicemic. Based on the story of Indonesian, the flushing of white durian skin commonly drunk after eating durian fruit can decrease the dizzy allegedly due to too high glucose levels that cause hyperglycemia.

   • According to Muhtadi M (2016)

     Excerpt This research study aimed to explore the antidiabetic & antihypercholesterolemia activities of rambutan (Nephelium lappaceum L.) & durian (Durio zibethinus Murr.) fruit peels extracts. Diabetic rats induced by alloxan intra-peritoneal at dose 150 mg/kg.bw.

   • According to Primarianti AU (2015)

     Excerpt The ethanolic extract of Durian (Durio zibethinus Murr.) & Rambutan (Nephelium lappaceum L.) fruit peels administered orally to the diabetic rats for 11 days, produced significant decrease in the level of blood glucose. The present study was carried out to evaluate the in alloxan (150 mg/kgb.wt) induced diabetic rats.

   • According to Sinulinggs BO (2020)

     Excerpt Durian or Durio zibethinus is a tropical fruit originating from Southeast Asia. In fact, several studies have proven the health benefits of durian fruit such as antimicrobial, ant diabetic, ant cholesterol, antioxidant, antiproliferative, antibacterial, antifungal, & others.

   • According to Tran HK (2023)

     Excerpt Durian (Durio zibethinus) fruit rinds are a promising source of bioactive phytochemicals, but they are currently wasted.

3. 3

   Bacterial infection: Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chigurupati S (2018)

     Excerpt DZLM exhibited the highest MIC & MBC of 250 μg/mL & 500 μg/mL respectively, against Bacillus subtilis & Staphylococcus aureus. In the present study, endophyte was isolated from the leaves of Durio zibethinus.

   • According to Pholdaeng K (2010)

     Excerpt PG from the fruit-rind of Durio zibethinus has been characterized to be a pectic polysaccharide with immunomodulating and antibacterial activities. Relative percent survival (RPS) values in groups fed the 2% PG-supplemented diet showed the highest RPS value for disease resistance of 100% (at Day 6) & 36% (at Day 4) in treated shrimp against viral & bacterial infection, respectively.

   • According to Abdul E.A (2024)

     Excerpt The incidence of antifungal resistance to Candida albicans infections has been growing over the past years; therefore, innovations are required to develop medicinal plants with antifungal properties such as durian fruit peels (Durio zibethinus Murray) that contain significant of bioactive compounds with antifungal properties. This study highlights that the ethanol extract of DZ has potential antifungal activity against C.A.

   • According to Mazila Ramli AN (2021)

     Excerpt This investigation was aimed to explore antibacterial & antioxidant compounds in Durio zibethinus (Durian) peel/seed extracts & their effectiveness in preventing meat decay. The antibacterial ability of sample extract was proven by the inhibition zone observed in the agar plate containing four foodborne pathogens.

   • According to Vimolmas Lipipun (2002)

     Excerpt Vimolmas Lipipun et al, Antimicrobial activity (in vitro) of polysaccharide gel from durian fruit-hulls, Songklanakarin J.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.