Eleusine indica (Houndstooth) : medicinal properties in alcoholic extraction

Eleusine indica (Houndstooth, Pié-poul, pied-de-poule) — family Poacées.

Scientific synonyms : ------.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 45 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to OKOKON TE (2010)

     Excerpt the ethanolic leaf extract of Eleusine indica used as antidiabetic and malarial remedy in Niger delta region of Nigeria was evaluated for antiplasmodial activity in Plasmodium berghei infected mice as well as hypoglycaemic & antidiabetic activities in alloxan-induced diabetic rats. Treatment of alloxan-induced diabetic rats with the leaf extract caused a significant (P<0.01) reduction in fasting Blood Glucose levels (BGL) of the alloxan-induced diabetic rats both in acute study and prolonged treatment (2 weeks).

   • According to Responte MA (2015)

     Excerpt In this study, BSLA was employed to evaluate the potential cytotoxic properties of the whole plant extracts of Eleusine indica. indica after 6 h exposure to mixture extract was 153.99 ppm, while the ethanolic extract obtained an LC50 of 409.73 ppm.

2. 2

   Cancer: adjuvant treatment for breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rollon AMD (2019)

     Excerpt Eleusine indica is a local medicinal plant that exhibits antioxidant, antimicrobial, & anticancer properties (Iberahim, 2015). (2009) wherein the ethanolic extract of EI was tested against human breast cancer cells & the results showed low IC50 values, the three trials conducted by the researchers using E.I on human lung cancer cells showed that the plant is not cytotoxic to cell line A549.

   • According to Hansakul P (2009)

     Excerpt (Yaa paak khwaai) & Eleusine indica (L.) Gaerth. All the grass extracts exhibited selective growth inhibition effect on human lung cancer (A549) & cervical cancer (HeLa) cells relative to normal human lung MRC-5 fibroblasts with IC 50 values in a range of 202 to 845 mg/ml.

   • According to Al-Zubairi AS (2009)

     Excerpt Therefore, the aim of this study was to screen the hexane, dicholoromethane, ethyl acetate (EA) & methanol extracts (MeTH) of EI for their antioxidant, antibacterial and anti-cancer effects using total phenolic contents (TPCs) and DPPH, disc diffusion method and MTT cytotoxicity assays, respectively. None of the extracts showed significant cytotoxic activity towards MCF-7, HT-29 and CEM-SS human cancer cell lines after 72 h incubation time (IC(50) > 30 μg/ml).

   • According to Nas JS (2020)

     Excerpt Aim: Hence, we evaluate the anticancer potential of EI methanolic leaf extract (EMLE) by focusing on two cancer-related pathways, Ras & Wnt pathways. In the Philippines, many accounts have resurfaced claiming different herbal & therapeutic advantages of Eleusine indica.

3. 3

   Inflammatory conditions: osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Nwaforp A (2014)

     Excerpt indica extract has anti-inflammatory & analgesic potentials that can be exploited in the management of pain & inflammatory condition. The plant Eleucine indica has a long ethnobotanical history because of its use in the treatment painful & inflammatory conditions.

   • According to Akah PA (2020)

     Excerpt The anti-inflammatory activities of the ethanol extract (EE) & ethylacetate fraction (ETF) & their possible mechanisms of actions were investigated. Conclusion: The mechanisms of the anti-inflammatory activity may involve among others inhibition of leukocyte migration & membrane stabilization.

   • According to Ettebong EO (2014)

     Excerpt Ettebong EO et al, Anti-inflammatory & analgesic potentials of Eleusine indica.

   • According to Ettebong EO (2017)

     Excerpt Eleusine indica is a medicinal plant used by the Ibi bios of Nigeria in the treatment of malaria but its safety with chronic use has not been determined. The extract caused, at low doses, slight inflammation of the liver, spleen, lungs, kidneys & brain.

   • According to De Melo GO (2005)

     Excerpt he infusion of aerial parts (EI) of Eleusine indica Gaertn (Poaceae) is used in Brazil against airway inflammatory processes like influenza and pneumonia. indica against airway inflammatory processes.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.