Ervatamia divaricata (Double jasmine) : medicinal properties in alcoholic extraction

Ervatamia divaricata (Double jasmine, Jasmen-Boutjèt, Bouquet jasmine, Jasmen-doub, Jasmin double, Jasmin-à-bouquet) — family Apocynacées.

Scientific synonyms : Nerium divaricatum-L, Coronarium-Jacq, Tabernaemontana divaricata-(L)-R.Br, T Coronaria-(Jacq)-Willd.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 29 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Liver cancer

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Poornima K (2014)

     Excerpt This study is an attempt to evaluate the hepatoprotective activity of Tabernaemontana divaricata against DEN and Fe NTA induced liver necrosis in rats. Ethanolic extract of the whole plant of TD at doses of 200 & 400 mg/kg body weight 1 5-fluorouracil (standard drug) was orally administered to male Wistar Albino rats once daily for 24 weeks, simultaneously treated with the carcinogen DEN & Fe NTA.

   • According to Parthiban S (2015)

     Excerpt BURKILL AGAINST EHRLICH ASCITES CARCINOMA, Int J of Pharm & Pharmaceut Sci, 7(7), 2015--Objective: The present study aims to evaluate the anti-tumor potential of EEED (ethanolic extract of Ervatamia divaricata) on EAC (Ehrlich ascites carcinoma). Parthiban S et al, ANTI-TUMOR POTENTIAL OF ERVATAMIA DIVARICATA.

   • According to Puranik SI (2018)

     Excerpt Materials & Methods: The present study involves at screening of preliminary phytochemicals, determination of total phenolic contents, evaluation of methanol, ethanol & aqueous leaf extracts of TD using in vitro 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) assay, ferricion reducing antioxidant power (FRAP) assay, Phosphomolybdenum (PM) method é evaluation of in vitro anticancer activity on T-24 human bladder cancer cell line. To investigate n vitro antitoxicity & anticancer activities from leaf extracts of Tabernaemontana divaricata.

   • According to Sivaraj R (n.d.)

     Excerpt Functional groups & chemical composition of zinc oxide were also confirmed Tabernaemontana mediated zinc oxide Nanoparticles showed effective cytotoxic effect against MCF -7 breast cancer cel l lines with an IC 50 value of 30.65 μg/ml/24 h by the MTT assay. The main objective of this study is to synthesize zinc oxide Nanoparticles from Tabernaemontana divaricata leaves through a green chemistry approach.

   • According to Author (2019)

     Excerpt In the present study, gas chromatography–mass spectrometry analysis was conducted to determine the occurrence of different phytochemical compounds in ethanolic flower extract of Tabernaemontana divaricata, Results: The ethanol extract of flower revealed the presence of several bioactive compounds such as n-hexadecanoic acid, squalene, Vitamin D3, Vitamin A aldehyde, desulfosinigrin, & Urs-12-en-24-oic acid, 3-oxo-, methyl ester, (+)-. Conclusion: The perceived compounds from ethanolic extract of flower have diverse beneficial properties such as antimicrobial, antioxidant, cancer anticipatory effect, pesticide, & antiarthritic,.

2. 2

   Liver conditions: cirrhosis, jaundice, fatty liver disease

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Poornima K (2014)

     Excerpt This study is an attempt to evaluate the hepatoprotective activity of Tabernaemontana divaricata against DEN and Fe NTA induced liver necrosis in rats. Ethanolic extract of the whole plant of TD at doses of 200 & 400 mg/kg body weight 1 5-fluorouracil (standard drug) was orally administered to male Wistar Albino rats once daily for 24 weeks, simultaneously treated with the carcinogen DEN & Fe NTA.

3. 3

   Adjuvant treatment for clear cell renal carcinoma

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Puranik SI (2018)

     Excerpt Materials & Methods: The present study involves at screening of preliminary phytochemicals, determination of total phenolic contents, evaluation of methanol, ethanol & aqueous leaf extracts of TD using in vitro 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) assay, ferricion reducing antioxidant power (FRAP) assay, Phosphomolybdenum (PM) method é evaluation of in vitro anticancer activity on T-24 human bladder cancer cell line. Morphological variations was observed in cancerous cells undergoing cell shrinkage é membrane blebbing in human bladder cancer cell line T-24 while the extract showed no cytotoxicity towards normal cells MEF-L929.

   • According to Sivaraj R (n.d.)

     Excerpt Functional groups & chemical composition of zinc oxide were also confirmed Tabernaemontana mediated zinc oxide Nanoparticles showed effective cytotoxic effect against MCF -7 breast cancer cel l lines with an IC 50 value of 30.65 μg/ml/24 h by the MTT assay. The main objective of this study is to synthesize zinc oxide Nanoparticles from Tabernaemontana divaricata leaves through a green chemistry approach.

   • According to Parthiban S (2015)

     Excerpt BURKILL AGAINST EHRLICH ASCITES CARCINOMA, Int J of Pharm & Pharmaceut Sci, 7(7), 2015--Objective: The present study aims to evaluate the anti-tumor potential of EEED (ethanolic extract of Ervatamia divaricata) on EAC (Ehrlich ascites carcinoma). Parthiban S et al, ANTI-TUMOR POTENTIAL OF ERVATAMIA DIVARICATA.

   • According to AKHILA SD (2012)

     Excerpt The Invitro anticancer studies were performed against human cancer cell line (HeLa) & MTT assay was used to analyze the cell growth inhibition. Tabernaemontana divaricata a native of India & many other tropical regions is a common Garden plant that has been used traditionally for treatment of a number of diseases.

   • According to Author (2019)

     Excerpt In the present study, gas chromatography–mass spectrometry analysis was conducted to determine the occurrence of different phytochemical compounds in ethanolic flower extract of Tabernaemontana divaricata, Results: The ethanol extract of flower revealed the presence of several bioactive compounds such as n-hexadecanoic acid, squalene, Vitamin D3, Vitamin A aldehyde, desulfosinigrin, & Urs-12-en-24-oic acid, 3-oxo-, methyl ester, (+)-. Conclusion: The perceived compounds from ethanolic extract of flower have diverse beneficial properties such as antimicrobial, antioxidant, cancer anticipatory effect, pesticide, & antiarthritic,.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.