Erythrina variegata (Motel) : medicinal properties in alcoholic extraction

Erythrina variegata (Motel, Immortelle, Holocaust, Judas tree, Môtèl, Holocauste, Arbre-de-Judas) — family Fabacées.

Scientific synonyms : Corallodendron orientalis (L.) Kuntze, Erythrina divaricata DC., E Picta l, E variegata Linn. var. orientalis (L.) Merr..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 18 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 91 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Thangamuneswari P (2017)

     Excerpt The aim of the present study is to evaluate the In vitro anti-diabetic analysis and antibacterial activities of hydroethanolic extract of Erythrina variegata leaves. The antibacterial activity of hydroethanolic extract of Erythrina variegata leaves were tested against Gram positive and Gram-negative species by the zone of inhibition.

   • According to Kumar A (2011)

     Excerpt variegata leaf demonstrated promising hypoglycemic action in STZ-induced diabetic rats substantiating its ethnomedicinal use. variegata leaf (MEEV) in streptozotocin (STZ)-induced diabetic Wistar rats.

   • According to Kumar A (2011)

     Excerpt variegata leaf demonstrated promising hypoglycemic action in STZ-induced diabetic rats substantiating its ethnomedicinal use. variegata leaf (MEEV) in streptozotocin (STZ)-induced diabetic Wistar rats.

   • According to Nagar JC (2015)

     Excerpt The present study was carried out to evaluate the hypoglycemic & hypolipidemic activity of alcohol & aqueous root extracts of Erythrina variegata in alloxan induced diabetic rats. The results showed that the extracts 300 mg/kg & 600 mg/kg significantly (P<0.001, p<0.01) reduced fasting blood glucose of alloxan diabetic rats in a dose-related manner, when compared to control and standard (anti-diabetic agent, Glibenclamide 500μg/kg).

   • According to Nagaraj S (2016)

     Excerpt our study focused to investigate the phytochemical analysis, quantification of bioactive compounds (alkaloid, phenols, flavonoids), in vitro free radical scavenging activity, anti-inflammatory activity (Membrane stabilization assay), in vitro anti-diabetic activity by enzyme inhibition activity, glucose uptake assay in isolated rat hemi-diaphragm & in yeast cells and also record GC-MS profile of Erythrina variegata bark (methanolic extract) which has boundless medicinal properties. GC-MS analysis of methanolic extract of E variegata bark revealed the presence of 58 compounds which are responsible for pharmacological activities.

2. 2

   Cancer: adjuvant treatment of basal cell alveolar adenocarcinoma of the liver and osteosarcoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Herlina T (2017)

     Excerpt Erythrina variegata is a herbal plant commonly used in Indonesia traditional medicine for treatment malaria disease. Histopathological examination showed an increased damage of liver & kidney cells in form hydropic degeneration, fatty degeneration, as well as necrosis along with increased of extract doses that significantly different with control (p<0.05).

   • According to Venkateswarlu B (2013)

     Excerpt Venkateswarlu B et al, HEPATOPROTECTIVE EFFECT OF ERYTHRINA VARIEGATA AGAINST CARBON TETRACHLORIDE (CCL4) INDUCED HEPATOTOXICITY IN WISTAR ALBINO RATS, Inter J of Preclinical & Pharmaceut Res.

   • According to Bharati SV (2019)

     Excerpt To study the anticancer potential & separation of essential oil from flowers of Erythrina indica, Materiel & methods: Antibacterial efficiency was checked by well diffusion method. aureus extract was effective against both the cell lines with the cytotoxicity % of 71.26 towards HepG2 & against MG-63 showed 67.11.

   • According to Bharathi SV (2019)

     Excerpt To study the anticancer potential & separation of essential oil from flowers of Erythrina indica. It was identified that the flower ethanol extract was effective against both the cell lines with the cytotoxicity % of 71.26 towards HepG2 & against MG-63 showed 67.11.

   • According to Baskar N (2010)

     Excerpt Baskar N et al, Anti-Cancer Activity of Methanol Extract of Root Bark of Erythrina variegata Linn.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Balamurugan G (2010)

     Excerpt The ethanolic extract of the leaves of Erythrina variegata leaves (Fabaceae) were screened for its antiinflammatory activity. The prevention of hypotonicity induced HRBC membrane lysis was taken a measure of anti-inflammatory activity.

   • According to Kumar A (2010)

     Excerpt This review gives an account of the current knowledge on the morphology, phytochemistry & pharmacological aspects of Erythrina variegata. The alkaloids extracted from the leaves of EV are reported to have anti-inflammatory & analgesic activity.

   • According to Murugalakshmi M (2017)

     Excerpt Anti-inflammatory activity of aqueous extract has shown significant activity in carrageenan induced paw oedema model in rats. Leaves of erythrina variegate were extracted with water successively.

   • According to Jimenez-Cabrera T (2020)

     Excerpt Over time, it has been learned that there is no single way to relieve pain, & as long as there are no other alternatives, the trend will continue to apply multidisciplinary management, such as promote the traditional use of the Erythrina genus to manage pain & inflammation. This review analyzes the decisive role that the Erythrina genus could play in managing inflammatory pain mediated by its compounds & its uses as an antioxidant.

   • According to Thongmee P (2016)

     Excerpt The bark of Erythrina variegata Linn.(Ev) is used in Thai traditional medicine for the treatment of many diseases in Thailand & is an ingredient in the Mahanintangthong remedy (antipyretic) & Lomammapruek remedy (analgesic and anti-inflammatory). variegata showed potent anti-inflammation properties by inhibiting prostaglandins production through enzyme COX-2 and inhibitory activity against lipopolysaccharide induced nitric oxide production in RAW 264.7 cell lines with an IC50 value of 9.27±0.72 & 47.1±0.21 μg/ml, respectively.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.