Eugenia uniflora (Siriz-kôt) : medicinal properties in alcoholic extraction

Eugenia uniflora (Siriz-kôt, Pitenga, Cerise-à-côte) — family Myrtacées.

Scientific synonyms : Eugenia michelii-Lam, E parkeriana-DC, Stenolalyx micheli-Linn.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 78 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet. Mentioned synergistic association: CAMELLIA SINENSIS-(L)-O. Kuntze, var sinensis.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vinholes J (2017)

     Excerpt Camellia sinensis, the most consumed & popular beverages worldwide, & Eugenia uniflora, a Brazilian native species, have been already confirmed to have beneficial effects in the treatment of diabetes mellitus. uniflora over alpha-glucosidase, a key digestive enzyme used on the Type 2 diabetes mellitus (T2DM) control.

   • According to Brunetti, R.C. (2006)

     Excerpt We investigated the effects of aqueous, butanol, & methanol extracts of Eugenia punicifolia leaves administered by gavage to streptozotocin-diabetic rats for 26 to 29 days.

   • According to Da Silva I (2019)

     Excerpt Eugenia uniflora is a plant found in several countries of South America & is traditionally used in folk medicine as an antimicrobial, anti‐inflammatory, & antihypertensive agent. Objective: This study aimed to investigate the neuroprotective effect of the ethanolic extract of EU leaves on memory impairment induced by streptozotocin (STZ) in rats.

   • According to Matsumura T (2000)

     Excerpt The water-soluble extract from a Paraguayan natural medicine, Ñangapiry, the leaves of Eugenia uniflora L. (Myrtaceae), which has been used as an antidiabetic agent, was found to show inhibitory activities on the increase of plasma glucose level in the sucrose tolerance test (STT) conducted with mice.

   • According to Mamose Y (1999)

     Excerpt Mamose Y et al, Improving effects of the extract from Eugenia uniflora.

2. 2

   Cancer: adjuvant treatment for breast, pancreatic and prostate cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ismayati N (2012)

     Excerpt The aim of the present study was to identify the antiproliferative effect of ethanolic extract of Eugenia Uniflora Lam. leaves (EEU) on breast cancer cell line T47D.

   • According to Aladesanmi AJ (2020)

     Excerpt The alcoholic extracts of the plants were tested against human prostate DU-145, breast JIMT-1, & pancreatic BxPC-3 cancer cell lines using Methane-thiosulfonate (MTS) assay, where chlorambucil was used as positive control. The study investigated eight Nigerian medicinal plants: Artocarpus communis fruit (Ac-F), Cassia sieberiana root bark (Cs-R), Eugenia uniflora leaf (Eu-L), Hibiscus rosa-sinensis flower (Hr-F), Laportea aestuans aerial part (La-A), Massularia acuminata stem bark (Ma-S), Trichilia heudelotii leaf (Th-L), & Xylopia aethiopica fruit (Xa-F), for anticancer activity.

   • According to Blanchin Gomes D (2020)

     Excerpt In this work, the antiproliferative effects of hydroethanolic (HEE) & dichloromethane (DEE) extracts of leaves from EU against a panel of human tumor cell lines in vitro were evaluated. The species Eugenia uniflora L.

   • According to Lee M (2000)

     Excerpt Nasopharyngeal carcinoma (NPC) is one of the high population malignant tumors among Chinese in southern China & southeast Asia.

   • According to De Oliveira FMG (2024)

     Excerpt Therefore, the activity of the ethanolic extract and aqueous fraction for gastric cancer & against H-pylori seems to originate from the antiproliferative & bacteriostatic effects of tannins & flavonoids. Eugenia uniflora leaves are a source of flavonoids & ellagitannins, & the Brazilian population uses them to treat various diseases, including gastrointestinal disorders.

3. 3

   Fungal infection: Aspergillus flavus, A. parasiticus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Chakravartula, S.S.N (2020)

     Excerpt Positive antifungal effect of NA containing films was observe-d against Aspergillus flavus & A parasiticus, indicating potential for active food packaging applications. The aim of this work was to develop & characterize film-forming solution & film based on blends of cassava starch/chitosan (CS/CH) incorporated with pitanga (Eugenia uniflora L.) leaf extract (PE) and/or natamycin (NA), produced by casting, and studying their effect on selected physical properties, & antioxidant & anti-fungal activities of films.

   • According to Santos KKA (2013)

     Excerpt Ethanol extract from Eugenia uniflora was assayed, for its antifungal activity, either alone or combined with four selected chemotherapeutic antimicrobial agents, including anphotericin B, mebendazole, nistatin, & metronidazole against these strains. However, no synergistic activity against the other strains was observed, as observed when the extract was associated with the other, not enhancing their antifungal activity.

   • According to Coutinho H (2010)

     Excerpt & Eugenia uniflora L. were screened for light – activated antibacterial activity against strains of Staphylococcus aureus, Escherichia coli & Pseudomonas aeruginosa.

   • According to JOVITO VC (2011)

     Excerpt The aim of this study was to evaluate the in vitro activity of dentifrices containing the hydroalcoholic extract of the of Eugenia uniflora L. To determine the antibacterial activity, the technique used was the minimum inhibitory concentration by the diffusion method in solid culture medium.

   • According to Schapoval EE (1994)

     Excerpt Antibacterial activity was evaluated based on minimum inhibitory concentrations (MICs) determined using the agar dilution method. uniflora Linn leaves were shown by chromatographic analysis in order to conduct a phytochemical characterization.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.