Evolvulus alsinoides (Bléyè) : medicinal properties in alcoholic extraction

Evolvulus alsinoides (Bléyè, Cornflower, Bleuet) — family Convolvulacées.

Scientific synonyms : Convolvulus alsinoïdes L, C linifolius L, C valerianoides Blanco, Evolvulus albiflorus M. Martens & Galeotti, E chinensis Choisy, E debilis Kunth, E filiformis Willd ex Steud, E ramiflorus Boj ex C..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 57 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gomathi D (2013)

     Excerpt alsinoides and standard drug resulted in the reduction of glycoproteins when compared with the diabetic control rats. The diabetes was induced by a single intraperitoneal injection of streptozotocin at 45 mg/kg body weight.

   • According to Gupta P (2007)

     Excerpt Bioactivity-guided purification of n-BuOH soluble fraction from the ethanol extract of Evolvulus alsinoides resulted in the isolation of two new compounds, 2,3,4-trihydroxy-3-methylbutyl 3-[3-hydroxy-4-(2,3,4-trihydroxy-2-methylbutoxy)-phenyl]-2-propenoate (1) & 1,3-di-O-caffeoyl quinic acid methyl ester (2) along with six known compounds, caffeic acid (3), 6-methoxy-7-O-bêta-glucopyranoside coumarin (4), 2-C-methyl erythritol (5), kaempferol-7-O-bêta-glucopyranoside (6), kaempferol-3-O-bêta-glucopyranoside (7) & quecetine-3-O-bêta-glucopyranoside (8). Compound 1 displayed most promising antistress effect by normalizing hyperglycemia, plasma corticosterone, CK & adrenal hypertrophy, while compounds 2 & 3 were also effective in normalizing most of these stress parameters, however compounds 4, 5 & 8 were ineffective in normalizing these parameters.

   • According to Gomathi D (2013)

     Excerpt This study showed that the administration of E alsinoides to streptozotocin induced diabetic rats improves the antioxidant activity & remodel the structure of pancreas due to the presence of secondary metabolites like phenols, flavonoids, alkaloids, steroids, terpenoids & glycosides in the ethanolic extract of plant material. Results: Oral administration of plant extract for 45 days resulted in significant antioxidant activity, increases the insulin level & also inhibits lipid peroxidation in pancreas of streptozotocin induced diabetic rats.

   • According to Gomathi D (2013)

     Excerpt This study showed that the administration of E alsinoides to streptozotocin induced diabetic rats improves the antioxidant activity & remodel the structure of pancreas due to the presence of secondary metabolites like phenols, flavonoids, alkaloids, steroids, terpenoids & glycosides in the ethanolic extract of plant material. Results: Oral administration of plant extract for 45 days resulted in significant antioxidant activity, increases the insulin level also inhibits lipid peroxidation in pancreas of streptozotocin induced diabetic rats.

   • According to Babu K (2007)

     Excerpt Compound 1 displayed most promising antistress effect by normalizing hyperglycemia, plasma corticosterone, CK & adrenal hypertrophy, while compounds 2 & 3 were also effective in normalizing most of these stress parameters, however compounds 4, 5 & 8 were ineffective in normalizing these parameters,.

2. 2

   Diarrhoea

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to LEKSHMI UMD (2011)

     Excerpt This study has proved scientifically the ancient claim that the whole plant of E alsinoïdes has antiinflammatory, antipyretic & antidiarrhoeal activities. The ethanolic extract of the whole plant of Evolvulus alsinoïdes L.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Whole plant.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to LEKSHMI UMD (2011)

     Excerpt This study has proved scientifically the ancient claim that the whole plant of E alsinoïdes has antiinflammatory, antipyretic & antidiarrhoeal activities. The ethanolic extract of the whole plant of Evolvulus alsinoïdes L.

   • According to Cervenka Department of Pharmaceutical Botany & Ecology, Faculty of Pharmacy, Charles Univ, Hradec Kralove, Czech Republic F (2008)

     Excerpt Evolvulus alsinoïdes (Convolvulaceae) is a plant used in traditional medicine of East Asia in many indications & has known nootropic & anti-inflammatory activity.

   • According to Reddy PA (2013)

     Excerpt The chloroform & Ethyl acetate extracts of the plant have significant anti-inflammatory activity by both methods that is carrageenan & formalin induced paw oedema in rats at 200 & 400mg/kg body weight. The aim of the study was to highlight the anti-inflammatory activity of Evolvulus alsinoïdes, it belongs to the family Convolvulaceae & commonly known as Shankpushpi.

   • According to -Mulukuri NVL (2017)

     Excerpt It has also been found effective in anxiety, neurosis, & memory invigoration & used in cerebral abnormalities, epilepsy, insomnia, burning sensation, Oedema, urinary disorders, & snakebites. Evolvulus alsinoïdes (Shankpushpi) is a reputed drug of Ayurveda & reported as a brain tonic, nervine tonic, & laxative.

   • According to Khan A (2016)

     Excerpt Therapeutic uses of Sankhaholi EA, mentioned in the Unani medicine are alexiteric (Mufarreh), cardiac tonic (Muqawwi-e Qalb), brain tonic (Muqawwi-e Dimag), digestive (Hazim) Musaffi-e-Khoon (blood purifier), general tonic (Muqawwi-e-am), diuretic (Mudirr-e-Baul), anti-inflammatory (Muhallil-e-waram), hypoglycemic (Dafa-e-Ziabitus), & antihypertensive (Dafye Imtella).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.