Ficus carica (Fig-frans) : medicinal properties in alcoholic extraction

Ficus carica (Fig-frans, French fig tree, Mexican medlar, Figuier de France, Néflier du Mexique) — family Moracées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 71 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of colorectal, liver, laryngeal and breast cancer

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Bad-Gujar SB (2014)

     Excerpt Conclusion: FC has emerged as a good source of traditional medicine for the treatment of various ailments such as anemia, cancer, diabetes, leprosy, liver diseases, paralysis, skin diseases, & ulcers. Ficus carica Linn (Moraceae) has been used in traditional medicine for a wide range of ailments related to digestive, endocrine, reproductive, & respiratory systems.

   • According to Mostapha K (n.d.)

     Excerpt The current study sought to screen, for the first time, a Ficus carica variety from the Shandong province of China against hepatocellular (HepG2) cells. Thus, it suggests that FLA may be a potential source of new drugs in the treatment of liver cancer.

   • According to Madrigal-Santillan E (2024)

     Excerpt Different parts of Ficus plants (root, stem bark, latex, leaves, pulp & fruits) contain bioactive compounds [flavonoids (flavanols, flavones, flavonols, isoflavones, chalcones, anthocyanins), phenolic acids (hydroxycinnamic acids, hydroxybenzoic acids), phytosterols, terpenes (triterpenes, tetraterpenes, diterpenes, sesquiterpenes, monoterpenes), coumarins, hydroxybenzoates, phenylpropanoids, chlorins, pheophytins, megastigmanes, chitinases, organic acids, fatty acids, amino acids, alkaloids, glycosides] which together, are currently useful to more than 30 traditional ethnomedical uses. This first review (Part 1), compiles information from published research (in vitro, in vivo & clinical studies) on its antimicrobial, antifungal, antiviral, anti-helminthic, hypoglycemic, hypolipidemic, hepatoprotective, anti-inflammatory, analgesic, & antipyretic properties; as well as its possible adverse and/or toxicological effects.

   • According to RUFA I UZ (2015)

     Excerpt The objective of this study was therefore to determine the antiproliferative activity and non-Toxic effect of dried preserved fruit extracts of Ficus carica on estrogen/progesterone receptor positive breast cancer cell (MCF-7) & mouse epithelial cell (3T3). These finding suggest that crude extracts of Ficus carica fruit have antiproliferative effect on the estrogen/progesterone receptor positive breast cancer cells.

   • According to Park S (2013)

     Excerpt The edible fruit of common fig (Ficus carica) or just the fig has been traditionally used for treating hemorrhoids, Insect stings, gout, ulcers, & skin infections such as warts and viruses. Tumor necrosis factor-α level also decreased significantly in all groups tested.

2. 2

   Type II diabetes mellitus

   Plant part used: fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Gilani AH (2008)

     Excerpt 119:1–5, 2008.-Ethnopharmacol Relevance: The ripe dried fruit of Ficus carica commonly known as “Fig” has medicinal value in traditional system of medicine for its use in gastrointestinal & inflammatory disorders. Gilani AH et al, Ethnopharmacological studies on antispasmodic & antiplatelet activities of Ficus carica.

   • According to Ramgopa Mopuri (2016)

     Excerpt Ramgopa Mopuri et al, Antidiabetic & Antiobesity activity of Ficus carica: In vitro experimental studies, Diabetes & Metabolism, 45(4), 2016-Aim : The present study was aimed to investigate the role of Ficus carica L. The ethanolic extract of F carica fruit was significantly (P < 0.05) more active than all other extracts & parts of the plant in terms of antioxidative, antidiabetic & anti-obesogenic activities.

   • According to Paramanya A (2023)

     Excerpt Among medicinal plants, FC has been widely used since ancient times & possesses many health-promoting activities like antidiabetic, antioxidant, antiobesity, anti-inflammatory, etc. In this book chapter, the importance of FC phytochemicals in preventing diabetes, glycation, oxidative stress, & secondary complication of diabetes will be reviewed.

   • According to Madrigal-Santillan E (2024)

     Excerpt Different parts of Ficus plants (root, stem bark, latex, leaves, pulp & fruits) contain bioactive compounds [flavonoids (flavanols, flavones, flavonols, isoflavones, chalcones, anthocyanins), phenolic acids (hydroxycinnamic acids, hydroxybenzoic acids), phytosterols, terpenes (triterpenes, tetraterpenes, diterpenes, sesquiterpenes, monoterpenes), coumarins, hydroxybenzoates, phenylpropanoids, chlorins, pheophytins, megastigmanes, chitinases, organic acids, fatty acids, amino acids, alkaloids, glycosides] which together, are currently useful to more than 30 traditional ethnomedical uses. This first review (Part 1), compiles information from published research (in vitro, in vivo & clinical studies) on its antimicrobial, antifungal, antiviral, anti-helminthic, hypoglycemic, hypolipidemic, hepatoprotective, anti-inflammatory, analgesic, & antipyretic properties; as well as its possible adverse and/or toxicological effects.

   • According to WANG W (2023)

     Excerpt In this research, the ultrasound-assisted extraction (UAE) conditions of the water-soluble polysaccharide (FCPS) from Ficus carica fruits were optimized using the response surface methodology. Meanwhile, FCPS effectively improved liver-related insulin resistance by promoting glucose consumption in hepatocytes & activated the immune response through activation of murine bone marrow-derived dendritic cells (DCs) & upregulation of interleukin 6 (IL6) & interleukin 12 (IL-12) expression.

3. 3

   Arthritis, osteoarthritis, rheumatism

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Paramanya A (2023)

     Excerpt Among medicinal plants, FC has been widely used since ancient times & possesses many health-promoting activities like antidiabetic, antioxidant, antiobesity, anti-inflammatory, etc.

   • According to ZHANG T (2024)

     Excerpt FC polysaccharides (FPs) are one of the key bioactive constituents of FC demonstrating various biological activities such as antioxidative, immunomodulatory, anti-inflammatory, & antitumor effects, among others. carica), commonly referred to as the fig tree, has received considerable attention due to its delectable and nutritious fruits.

   • According to Patil V (2011)

     Excerpt Leaves, Indian Jl of Nat Prod & Resources, 2(2) :151-5, 2011.-The aim of the present study was to explore the probable anti-inflammatory effect of petroleum ether (PEE), chloroform (CE) & ethanol (EE) extracts obtained from the leaves of Ficus carica. Patil V et al, Evaluation of anti-inflammatory activity of Ficus carica Linn.

   • According to Madrigal-Santillan E (2024)

     Excerpt This first review (Part 1), compiles information from published research (in vitro, in vivo & clinical studies) on its antimicrobial, antifungal, antiviral, anti-helminthic, hypoglycemic, hypolipidemic, hepatoprotective, anti-inflammatory, analgesic, & antipyretic properties; as well as its possible adverse and/or toxicological effects. Different parts of Ficus plants (root, stem bark, latex, leaves, pulp & fruits) contain bioactive compounds [flavonoids (flavanols, flavones, flavonols, isoflavones, chalcones, anthocyanins), phenolic acids (hydroxycinnamic acids, hydroxybenzoic acids), phytosterols, terpenes (triterpenes, tetraterpenes, diterpenes, sesquiterpenes, monoterpenes), coumarins, hydroxybenzoates, phenylpropanoids, chlorins, pheophytins, megastigmanes, chitinases, organic acids, fatty acids, amino acids, alkaloids, glycosides] which together, are currently useful to more than 30 traditional ethnomedical uses.

   • According to Abdel-Rahman R (2021)

     Excerpt Several studies have evaluated the beneficial properties of certain pharmaceutical molecules extracted from Ficus carica (FC). Natural extracted ingredients are evolutionarily selected molecules & are used to control inflammation & cancerous progression & transformation.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.