Ficus pumila (Ivy) : medicinal properties in alcoholic extraction

Ficus pumila (Ivy, Lierre) — family Moracées.

Scientific synonyms : Ficus repens-hort.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 39 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to THAMOTHARAN G (2013)

     Excerpt Objective: To find out the hypoglycaemic & hypolipidemic activities of ethanol leaf extract of Ficus Pumila is the main objective of the present study. Animals were treated with ethanol extract of Ficus Pumila (EEFP) and standard drug Glibenclamide for 21 days.

   • According to Qi Z (n.d.)

     Excerpt Accumulated studies have demonstrated that F pumila has multiple therapeutic activities, including antioxidant, anti-inflammatory, antibacterial, antitumor, hypoglycemic, & cardiovascular protective effects. Ficus pumila has been used as a functional plant for a long time in East Asia, especially its fruits, as a dietary component in Japan & parts of China.

   • According to GONDA K (2025)

     Excerpt (4) Conclusions: FP extract, ingested by patients who developed diabetes after COVID-19 infection, stimulated insulin secretion capacity & improved insulin resistance,. In this study, we investigated the effects of Ficus pumila L.

   • According to Suzuki K (2020)

     Excerpt We found that Ooitabi (Ficus pumila L.), a plant native to Okinawa, was useful for hypertension. Results: After 3 months, there were significant reductions in body mass index, systolic & diastolic blood pressure, total cholesterol, low‐density lipoprotein cholesterol, γ‐glutamyltrans peptidase, uric acid & ratio of blood vessel insulin resistance.

   • According to Xiao WL (n.d.)

     Excerpt Ficus pumila (Moraceae) has been used as a beverage or herbal medicine for treating diabetes, neuralgia, diarrhea, rheumatic arthralgias & high blood pressure in traditional Chinese medicine [1]. pumila was invest W 264.7 macrophages with IC50 value of 30.65 mM [16], while 5 was uniquely acquired from Taxus mairei & Cestrum parqui [17, 18].

2. 2

   Hepatitis, cirrhosis, fatty liver disease

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Larbie C (2018)

     Excerpt Ficus pumila has been reported to be rich in phenols, hepatoprotective & antiproliferative on leukemic cancer cells. The results suggest that hydro-ethanolic extract of F pumila leaves protect against gentamicin-induced nephrotoxicity in female Wistar albino rats,.

   • According to Larbie C (2016)

     Excerpt The general objective of the study was to determine the hepatoprotective effect of 50% hydroethanolic extract of Ficus Pumila on carbon tetrachloride (CCl 4) induced liver damage in rats. In this work, liver damage was induced in experimental animals by administering 1 ml/kg CCl 4 orally, after which the rats were treated with 50% hydroethanolic extract of FP & Silymarin, a standard hepatoprotective drug.

   • According to Torkornoo D (2015)

     Excerpt This study sought to evaluate the heavy metal content of the raw powder & extract of the plant, the phytochemical constituents, antioxidant effect by the use of DPPH assay, the total phenolic content using Folin Ciocalteu assay & the cytotoxic effect using the MTT Assay of Ficus pumila ethanolic extract, methanolic & hydro fractions on liver cancer cells (HepG2), Leukemic cells (Jurkat) & normal liver cells (Chang).

   • According to Liao CR (2012)

     Excerpt This study investigated possible analgesic & anti-inflammatory mechanisms of the methanol extract of Ficus pumila (FP(MeOH)). This study indicated anti-inflammatory mechanism of FP(MeOH) may be due to declined levels of NO & MDA in the edema paw through increasing the activities of SOD, GPx, & GRd in the liver.

   • According to Suzuki K (2020)

     Excerpt We found that Ooitabi (Ficus pumila L.), a plant native to Okinawa, was useful for hypertension. Of 3814 Japanese patients who underwent medical check‐ups in Okinawa, 38 individuals with high blood pressure, dyslipidaemia, liver dysfunction & gout visited our hospital as outpatients & were asked to drink Ishimaki tea.

3. 3

   Adjuvant treatment for leukaemia

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Larbie C (2015)

     Excerpt The objective for this study was, therefore, to determine the antiproliferative activity as well as phytochemical, total phenolic content (TPC), and antioxidant activity of the stem and leaf extracts (FPS and FPL) of Ficus Pumila (L.) using standard methods. Conclusion: These findings suggest that crude extracts of FPS & FPL have antiproliferative effect on the leukemia cells.

   • According to Qi Z (n.d.)

     Excerpt Accumulated studies have demonstrated that F pumila has multiple therapeutic activities, including antioxidant, anti-inflammatory, antibacterial, antitumor, hypoglycemic, & cardiovascular protective effects. Ficus pumila has been used as a functional plant for a long time in East Asia, especially its fruits, as a dietary component in Japan & parts of China.

   • According to Éphraïm PL (2009)

     Excerpt (Fig): Ethnobotany & potential as anticancer & anti-inflammatory agents.

   • According to Larbie C (2018)

     Excerpt Ficus pumila has been reported to be rich in phenols, hepatoprotective & antiproliferative on leukemic cancer cells. The results suggest that hydro-ethanolic extract of F pumila leaves protect against gentamicin-induced nephrotoxicity in female Wistar albino rats,.

   • According to LARBIE C (2016)

     Excerpt LARBIE C et al, ACUTE & SUB-CHRONIC TOXICITY OF AQUEOUS ETHANOLIC EXTRACT OF FICUS PUMILA LEAVES IN RATS, Eur J of Biomedical & Pharmaceut Sci, 3(8) :22-7, 2016-Abstract; -Ficus Pumila (creeping fig) is a popular ornamental plant in the tropical region. In an attempt to certify safety & support its medical & healthcare use, acute & Subchronic toxicity studies were carried out on the hydroethanolic leaf extracts of F Pumila in animals at doses of 100 mg/kg, 250 mg/kg & 500 mg/kg body weight using standard methods.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.