Genipa americana (Genipa) : medicinal properties in alcoholic extraction

Genipa americana (Genipa, Jénipa) — family Rubiacées.

Scientific synonyms : Gardenia genipa Sw., G americana var. americana, G americana var. caruto (Kunth) K.Schum., G caruto Kunth.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 63 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Escherichia coli, Staphylococcus aureus, S. intermedius, S. haemolyticus, Pseudomonas aeruginosa, MRSA and MLSB-Staphylococcus

   Plant part used: sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sousa Abreu PO (2023)

     Excerpt Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, MRSA & MLSB Staphylococcus hominis & Staphylococcus haemolyticus & Staphylococcus species were used as infective & biofilm-forming microorganisms. The aim of this study was to evaluate the disinfectant action & biofilm biomass reduction of the ethanolic extract of Genipa americana fruit.

   • According to Hurtado-Colmenares L (2024)

     Excerpt Genipap (Genipa americana L.), also known as caruto, is a fruit native to Central & South America & presents a novel source of a crosslinking substance containing genipin for biopolymers in various applications. The extracted GA oil shows a high phenolic content & remarkable nonhemolytic, antioxidant, & antimicrobial activity.

   • According to Chel-Guerrero LD (2022)

     Excerpt (Guava), Genipa americana L.

   • According to Gabas G (2015)

     Excerpt The ethanolic extract was tested against clinical isolates of Staphylococcus intermedius & Pseudomonas aeruginosa which were obtained from dogs presenting dermatitis. Genipa americana is widely distributed throughout the tropical, parts of the subtropical areas of Latin America & the savannah transition zone.

   • According to Campos Codignoto PS (2011)

     Excerpt The antimicrobial action on Escherichia coli & Staphylococcus aureus was performed by the agar diffusion & the microdilution methods ² by agar diffusion method against Candida albicans, C parapsilosis, C glabrata & Candida krusei. This study aimed to determine the in vitro toxicity of Genipa Americana & its antiviral & antimicrobial activities.

2. 2

   Fungal infection: Candida albicans, C. parapsilosis, C. glabrata and Candida krusei

   Plant part used: Aerial parts.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hurtado-Colmenares L (2024)

     Excerpt Genipap (Genipa americana L.), also known as caruto, is a fruit native to Central & South America & presents a novel source of a crosslinking substance containing genipin for biopolymers in various applications. The extracted GA oil shows a high phenolic content & remarkable nonhemolytic, antioxidant, & antimicrobial activity.

   • According to Campos Codignoto PS (2011)

     Excerpt The antimicrobial action on Escherichia coli & Staphylococcus aureus was performed by the agar diffusion & the microdilution methods ² by agar diffusion method against Candida albicans, C parapsilosis, C glabrata & Candida krusei. This study aimed to determine the in vitro toxicity of Genipa Americana & its antiviral & antimicrobial activities.

   • According to Chel-Guerrero LD (2022)

     Excerpt (Guava), Genipa americana L.

   • According to Sousa Abreu PO (2023)

     Excerpt The aim of this study was to evaluate the disinfectant action & biofilm biomass reduction of the ethanolic extract of Genipa americana fruit. The ethanolic extract of GA did not show optimal disinfectant action in the simulated critical environment; however, considering the reported antimicrobial action of this extract, more studies should be considered to find the best formula to improve this extract's disinfectant efficacy.

   • According to Gabas G (2015)

     Excerpt Genipa americana is widely distributed throughout the tropical, parts of the subtropical areas of Latin America & the savannah transition zone. We studied the presence of polyphenols & tested the antimicrobial & antioxidant activities of ethanol extract of GA Leaves were harvested in UPIS, Lagoa Bonita Farm, Planaltina-DF, Brazil.

3. 3

   Swine viral infection: SuHV-1 (Aujeszky’s disease)

   Plant part used: Pest control and veterinary products.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Hurtado-Colmenares L (2024)

     Excerpt Genipap (Genipa americana L.), also known as caruto, is a fruit native to Central & South America & presents a novel source of a crosslinking substance containing genipin for biopolymers in various applications. The extracted GA oil shows a high phenolic content & remarkable nonhemolytic, antioxidant, & antimicrobial activity.

   • According to Chel-Guerrero LD (2022)

     Excerpt (Guava), Genipa americana L.

   • According to Campos Codignoto PS (2011)

     Excerpt This study aimed to determine the in vitro toxicity of Genipa Americana & its antiviral & antimicrobial activities. Instead, the leaves & branch extracts showed antiviral activity against SuHV-1, with a viral inhibition of 73 & 79%, respectively, but no inhibition on EHV-1.

   • According to Sousa Abreu PO (2023)

     Excerpt The aim of this study was to evaluate the disinfectant action & biofilm biomass reduction of the ethanolic extract of Genipa americana fruit. The ethanolic extract of GA did not show optimal disinfectant action in the simulated critical environment; however, considering the reported antimicrobial action of this extract, more studies should be considered to find the best formula to improve this extract's disinfectant efficacy.

   • According to Gabas G (2015)

     Excerpt Genipa americana is widely distributed throughout the tropical, parts of the subtropical areas of Latin America & the savannah transition zone. We studied the presence of polyphenols & tested the antimicrobial & antioxidant activities of ethanol extract of GA Leaves were harvested in UPIS, Lagoa Bonita Farm, Planaltina-DF, Brazil.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.