Gliricidia sepium (Gliséria) : medicinal properties in alcoholic extraction

Gliricidia sepium (Gliséria) — family Fabacées.

Scientific synonyms : Robinia rosea-Mill, Robinia maculata-HBK, R. variegata-Schlecht, R. sepium-Jacq, longocharpus maculata-DC, gliciridia maculata-Steud, G. lambii-Fernald.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 54 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Bacterial infection: Staphylococcus aureus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to JOSE B (2010)

     Excerpt Essential oils from leaf & flower of Gliricidiasepium were tested for antibacterial activity against ten bacterial strains: Bacillus cereus, Enterobacter faecalis, Salmonella paratyphi, Staphylococcus aureus, Escherichia coli, Streptococcus faecalis, Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa & Serratia marcescens by ‘agar well diffusion’ method. The remarkable antibacterial activity exhibited by the leaf oil can be attributed to the synergic effect of the antimicrobial agents present in it.

   • According to Mathur A (2010)

     Excerpt The antimicrobial activity & minimum inhibitory concentration (MIC) of various plant extracts in different solvents such as ethanol (98%), hexane (99%) & distilled water of plants traditionally used as medicines as Bidens pilosa L., Bixa orellana L., Cecropia peltata L., Cinchona officinalis L., Gliricidia sepium, Jacaranda mimosifolia, Justicia secunda Vahl., Piper pulchrum, P. & Spilanthes americana were evaluated against five bacteria Staphylococcus aureus, Streptococcus hemolytic, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli & fungus Candida albicans.

   • According to Nazli R (2008)

     Excerpt Gliricidia sepium is an exotic plant belonging to the family Fabaceae. Using well diffusion method the antibacterial activity of ethanol extract against E.

   • According to Boboye B (2012)

     Excerpt The methanol, ethanol & petroleum ether soluble crude & fractions extract of Gliricidia sepium & Spathodea campanulata leaf were examined for antibacterial activities, phytochemicals & possible sources of antioxidant. The antibacterial activity of the crude & fractions were carried out against nine clinical bacteria isolates using the agar well & disc diffusion methods respectively.

   • According to Raju R (2021)

     Excerpt Three common medicinal plants in the Philippines, Gliricidia sepium (madre de cacao), Melothria pendula (wild pipino), & Pithecellobium dulce (Camachile), were studied to determine their phytochemical components. These secondary metabolites present on the leaf extract of the aforementioned plants have various pharmacological properties such as analgesic, anti-diarrheal, anti-inflammatory, & antimicrobial.

2. 2

   Fungal infection: Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mathur A (2010)

     Excerpt The antimicrobial activity & minimum inhibitory concentration (MIC) of various plant extracts in different solvents such as ethanol (98%), hexane (99%) & distilled water of plants traditionally used as medicines as Bidens pilosa L., Bixa orellana L., Cecropia peltata L., Cinchona officinalis L., Gliricidia sepium, Jacaranda mimosifolia, Justicia secunda Vahl., Piper pulchrum, P. & Spilanthes americana were evaluated against five bacteria Staphylococcus aureus, Streptococcus hemolytic, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli & fungus Candida albicans.

   • According to Nazli R (2008)

     Excerpt Gliricidia sepium is an exotic plant belonging to the family Fabaceae. Using well diffusion method the antibacterial activity of ethanol extract against E.

   • According to Boboye B (2012)

     Excerpt The methanol, ethanol & petroleum ether soluble crude & fractions extract of Gliricidia sepium & Spathodea campanulata leaf were examined for antibacterial activities, phytochemicals & possible sources of antioxidant. The antibacterial activity of the crude & fractions were carried out against nine clinical bacteria isolates using the agar well & disc diffusion methods respectively.

   • According to Raju R (2021)

     Excerpt Three common medicinal plants in the Philippines, Gliricidia sepium (madre de cacao), Melothria pendula (wild pipino), & Pithecellobium dulce (Camachile), were studied to determine their phytochemical components. These secondary metabolites present on the leaf extract of the aforementioned plants have various pharmacological properties such as analgesic, anti-diarrheal, anti-inflammatory, & antimicrobial.

   • According to JOSE B (2010)

     Excerpt The remarkable antibacterial activity exhibited by the leaf oil can be attributed to the synergic effect of the antimicrobial agents present in it. Essential oils from leaf & flower of Gliricidiasepium were tested for antibacterial activity against ten bacterial strains: Bacillus cereus, Enterobacter faecalis, Salmonella paratyphi, Staphylococcus aureus, Escherichia coli, Streptococcus faecalis, Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa & Serratia marcescens by ‘agar well diffusion’ method.

3. 3

   Oxidative stress

   Plant part used: Fruit.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to CACERES A (2012)

     Excerpt pepo, Erythrina berteroana, Fernaldia Pandurata, Gliricidia sepium, Lippia graveolens, Litsea guatemalensis, Manilkara sapota, Neurolaena lobata, Ocimum micranthum, Phlebodium pseudoaureum, Pimenta dioica, Piper auritum, Smilax domingensis, Solanum nigrescens, Spondias mombin, Tagetes lucida & Yucca éléphantipes). Antioxidant activity was evaluated by macro- & micro-quantification of total phenolics by Folin-Ciocalteu, total antioxidant capacity using DPPH, & Iron reducing power.

   • According to Oduola RA (2018)

     Excerpt Oduola RA et al, Use of Gliricidia sepium aqueous leaf extract as an antisickling agent: Oxidative stress biomarkers in wistar rats exposed to the extract, Int.

   • According to Gabule Ang A (2019)

     Excerpt Tithonia diversifolia & Gliricidia sepium are commonly growing in Bukidnon, Philippines. Material & Methods: Qualitative phytochemical screening & determination of Total Phenolic Content (TPC), Total Flavonoid Content (TFC), Total Antioxidant Capacity (TAC) & cytotoxicity of the ethanolic leaf extracts of T.

   • According to Boboye B (2012)

     Excerpt The methanol, ethanol & petroleum ether soluble crude & fractions extract of Gliricidia sepium & Spathodea campanulata leaf were examined for antibacterial activities, phytochemicals & possible sources of antioxidant. The antioxidant DPPH test was performed where appreciable level of both ferric reducing antioxidant properties & free radical scavenging activities were of better expression in SC than GS.

   • According to Ang AG (2019)

     Excerpt Tithonia diversifolia & Gliricidia sepium are commonly growing in Bukidnon, Philippines. Materials & Methods: Qualitative phytochemical screening & determination of Total Phenolic Content (TPC), Total Flavonoid Content (TFC), Total Antioxidant Capacity (TAC) & cytotoxicity of the ethanolic leaf extracts of T.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.