Hamelia patens (Flè-koray) : medicinal properties in alcoholic extraction

Hamelia patens (Flè-koray, Flower-Coral, Fleur-Corail) — family Rubiacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 15 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to PANDURANGAN A (2013)

     Excerpt Diabetes was confirmed after 5 days, after that Petroleum ether (PEHP) & Ethanolic extracts (EEHP) of Hamelia patens (100 & 400 mg/kg, body wt.) and the standard drug Glibenclamide (10 mg/kg, body wt.) were given orally in 0.5% Tween 80 daily for 20 days, except the normal and diabetic control group (n=6). Conclusion: From the result obtained in the present study, it is concluded that PEHP & EEHP (400 mg/kg, body wt.) possess better antidiabetic potential in alloxan induced diabetic rats.

2. 2

   Internal bacterial and fungal infections: Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella typhi, Aspergillus niger, Candida albicans

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Okoye EL (2014)

     Excerpt The antimicrobial activities against Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella typhi, Aspergillus niger and Candida albicans were evaluated using agar diffusion and broth dilution techniques in accordance with standard methods. Escherichia coli and Staphylococcus aureus were the most susceptible bacterial isolates to all the extracts used while Candida albicans was more susceptible to the extracts than the Aspergillus niger among the fungal isolates.

   • According to Khandelwal S (2012)

     Excerpt (Rubiaceae) Int J of Nat Prod Res, 1(3) :54-6, 2012.-The objective of the present investigation was to determine the Anthelmintic and antimicrobial activity of ethanolic extract of different parts (Leaf, stem and root) of Hamelia patens Jacq. Khandelwal S et al Anthelmintic&d antimicrobial activity of Hamelia patens Jacq.

3. 3

   Cancer: adjuvant treatment of breast cancer, lung cancer (non-small cell) and anaplastic astrocytoma

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vijay Raj B (n.d.)

     Excerpt Test groups were given standard Indomethacin (10mg/kg) and Hamelia patens leaf extract in 200mg/kg & 400mg/kg; after 1% Carrageenan (0.1 ml) injection. The present study investigates the anti-inflammatory activity of Hamelia patens leaf extracts using carrageenan induced paw edema in albino rats.

   • According to KUMAR S (2012)

     Excerpt In the present study we have done non-targeted analysis of extract from Hamelia patens by GC/MS & estimated the inhibitory concentration (IC50) of the extract in three human tumor cell lines MCF-7, H-460 & SF-268. In-vitro cytotoxic activity of HPAE on cancer cell lines were conducted by MTT assay.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.