Hemerocallis fulva (Red lily) : medicinal properties in alcoholic extraction

Hemerocallis fulva (Red lily, Lis wouj, Lys rouge) — family Asphodeliacées.

Scientific synonyms : Hemerocallis disticha Donn ex Sweet, H flava Suter, H lilioasphodelus var. fulva L., H crocea Lam..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 25 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for hepatocellular carcinoma: cultivar: Élégant Explosion

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ma T (2021)

     Excerpt Daylilies (Hemerocallis) are used medicinally in eastern Asia & extracts of the plant had been shown to inhibit cell proliferation & induce cancer cells to undergo differentiation. In our studies of the constituents of Hemerocallis fulva var.

   • According to Cichewicz RH (2004)

     Excerpt Daylilies (Hemerocallis) are used medicinally in eastern Asia & extracts of the plant had been shown to inhibit cell proliferation and induce cancer cells to undergo differentiation. In our studies of the constituents of Hemerocallis fulva var.

   • According to Li X (2021)

     Excerpt Meanwhile, modern pharmaceutical research has shown that many bioactive constituents display versatile pharmacological activities, such as anti-depression, antibacterial, anti-tumour, anti-oxidative, insecticide, sedative & hypnotic, thus providing a scientific basis for the further exploitation & utilisation of this important resource. Statistics as of 31 December 2020, showed that a total of 266 secondary metabolites including 110 volatile components, 41 flavonoids, 39 alkaloids, 29 terpenoids, 14 anthraquinones, 15 phenylpropanoids & 18 other types of compounds have been found in Hemerocallis plants.

   • According to Fu R (2020)

     Excerpt The in vitro cytotoxic activities of compounds 1 & 2 were studied against breast carcinoma MDA-MB-231, hepatocellular carcinoma HepG2 & lung carcinoma A549 cell lines. Two new phenanthrenes, Hemecitones A & B, were isolated from Hemerocallis fulva (L.) L.

   • According to Que F (2007)

     Excerpt Daylily (Hemerocallis fulva Linn.) flowers were hot air-dried & freeze-dried after harvest. Antioxidant proper- ties of water & ethanol extracts prepared from these dried flowers were evaluated in terms of total antioxidant activity, reducing capacity, & metal chelating activity.

2. 2

   Oxidative stress

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Mao LC (2013)

     Excerpt Daylily (Hemerocallis fulva Linn.) flowers were hot air-dried & freeze-dried after harvest. Water and ethanol extracts were prepared from these dried flowers & their antioxidant properties were evaluated using total antioxidant activity, reducing capacity, metal chelating activity, and DPPH & superoxide anion radical scavenging activities, comparing with standards.

   • According to Que F (2007)

     Excerpt Daylily (Hemerocallis fulva Linn.) flowers were hot air-dried & freeze-dried after harvest. Antioxidant proper- ties of water & ethanol extracts prepared from these dried flowers were evaluated in terms of total antioxidant activity, reducing capacity, & metal chelating activity.

   • According to Johnson J (2021)

     Excerpt Materials & Methods: BM & EE HF flowers extracts were prepared with aqueous ethanol & used to determine Total Phenolic Content (TPC), Total Flavonoid Content (TFC), Total Monomeric Anthocyanins (TMA), Condensed Tannins (CT) & antioxidant assays. Conclusion: With limited studies on polyphenol content & bioactivity of EE HF flower, these results provide preliminary evidence & contribute to the promotion of edible flowers as a potential dietary supplement & nutraceutical for use as functional foods.

   • According to Szewczyk K (2020)

     Excerpt The present study demonstrated that Hemerocallis cultivars contain significant amounts of phenolic compounds with good skin-related activities & could be interesting as novel sources of bioactive agents for the pharmaceutical, food & cosmetic industries. Hemerocallis plants are important vegetables with nutritional & health value, especially in eastern Asia, where they have been used as medicines to cure disease such as depression & inflammation for thousands of years.

   • According to Zhang Y (2004)

     Excerpt In studies of the aqueous methanol extracts of fresh H fulva leaves, 1′,2′,3′,4′-tetrahydro-5′-deoxy-pinnatanine (1), pinnatanine (2), roseoside (3), phlomuroside (4), lariciresinol (5), adenosine (6), quercetin 3-O-β-d-glucoside (7), quercetin 3,7-O-β-d-diglucopyranoside (8), quercetin 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranosol-7-O-β-d-gluco-pyranoside (9), isorhamnetin-3-O-β-d-6′-acetyl-gluco-pyranoside (10) & isorhamnetin-3-O-β-d-6′-acetylgalactopyranoside (11) were isolated. Compounds 3–5 & 7–11 were found to possess strong antioxidant properties, inhibiting lipid oxidation by 86.4, 72.7, 90.1, 79.7, 82.4, 89.3, 82.2, & 93.2%, respectively at 50 μg/mL.

3. 3

   Depression

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Lin SH (2013)

     Excerpt Daylily flower (金針花 Jīn Zhēn Huā ; the flower of Hemerocallis fulva) is traditionally used for soothing in Chinese dietary therapy. In this study, we investigated the antidepressant effects of ethanol extract of daylily flowers (DFEtoH) & rutin by forced swimming test (FST) & neurotransmitter metabolism of brain regions (frontal cortex, hippocampus, striatum, & amygdala).

   • According to Ma T (2021)

     Excerpt In our studies of the constituents of Hemerocallis fulva var. Daylilies (Hemerocallis) are used medicinally in eastern Asia & extracts of the plant had been shown to inhibit cell proliferation & induce cancer cells to undergo differentiation.

   • According to Li X (2021)

     Excerpt Meanwhile, modern pharmaceutical research has shown that many bioactive constituents display versatile pharmacological activities, such as anti-depression, antibacterial, anti-tumour, anti-oxidative, insecticide, sedative & hypnotic, thus providing a scientific basis for the further exploitation & utilisation of this important resource. Statistics as of 31 December 2020, showed that a total of 266 secondary metabolites including 110 volatile components, 41 flavonoids, 39 alkaloids, 29 terpenoids, 14 anthraquinones, 15 phenylpropanoids & 18 other types of compounds have been found in Hemerocallis plants.

   • According to Lin HY (2020)

     Excerpt This study aims to uncover the pharmacological mechanism of the antidepressant effect of Hemerocallis Radix (HR) through network pharmacology method. Its flower buds are known to have ability to clear away heat & dampness, detoxify, & relieve depression.

   • According to Szewczyk K (2019)

     Excerpt The horticultural cultivars of Hemerocallis (daylily) have been used to treat diseases such as insomnia, inflammation & depression, and also as a vegetable in eastern Asia. Taking into consideration the fact, that the volatile compounds in Hemerocallis cultivars have not been investigated to date, we decided to study the composition of the essential oils (EOs) from the aerial parts of ten varieties collecting in Poland.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.