Hibiscus rosa (Gwo-Kokliko) : medicinal properties in alcoholic extraction

Hibiscus rosa (Gwo-Kokliko, big poppy, gros Coquelicot) — family Malvacées.

Scientific synonyms : Hibiscus testalis-Salisb, H Boryanus-DC.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 26 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 52 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to SACHDEWA A (2013)

     Excerpt Blood glucose and total lipid levels were determined in streptozotocin induced diabetic rats after oral administration of an ethanol flower extract of H rosa sinensis. The Hypoglycemic activity of this extract is comparable to that of Glibenclamide but is not mediated through insulin release.

   • According to KAREL A (2022)

     Excerpt Hibiscus rosa-sinensis L. This study emphasizes the chemical composition, & uses of the plant for antioxidant & anti-diabetic activity as well as future prospects of harnessing its beneficial effects in the form of beverages.

   • According to SOHANI S (2021)

     Excerpt The medicinal value of the flower is described in the ancient science, Ayurveda & Chinese herbology A number of research studies proved that the different parts of Hibiscus rosa sinensis plants possesses Antioxidant, Antimicrobial, Antidiabetic, Antiulcer, Hepatoprotective, Antifertility, Antigenotoxic & Anti-inflammatory properties, which supports in treatment of countless diseases. Hibiscus rosa sinensis has been used in many herbal mix & drinks.

   • According to Venkatesh JS (2008)

     Excerpt Venkatesh JS et al, Antidiabetic activity of flowers of Hibiscus rosa sinensis, Fitoterapia, 79, (2) :79-81, 2008-Abstract:.

   • According to Mamun A (2013)

     Excerpt The present study was designed to investigate the effect of ethanolic extract of Hibiscus rosa sinensis (EHBS) leaves on alloxan-induced diabetes with Dyslipidemia in rats. Treatment of alloxan-induced diabetes with most effective observed dose (2.0 mg/kg body weight) of EHBS for 1 week significantly reduced glucose level, TC, TG & LDL-C, with the increase of HDL-C & weight of kidney, pancreas & liver when compared with diabetic rats.

2. 2

   Diabetes mellitus: type I

   Plant part used: Sheet. Mentioned synergistic association: Acanthus Montanus, Asystasia gangetica, Emilia coccinea-feuilles.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ojiako OA (2015)

     Excerpt The present study ascertained the capacities of crude aqueous & ethanolic leaf extracts of Acanthus Montanus, Asystasia gangetica, Emilia coccinea & Hibiscus rosa sinensis, as well as their Combinatorial formulations to ameliorate hyperglycemia in Type I diabetic rats. Individual hyperglycemic rats (HyGR) received separate doses of either 20 mg/kg bw/24 h of A Montanus (ACMO), A gangetica (ASGA), E coccinea (EMCO) or H rosa sinensis (HIRO), as well as their Combinatorial formulations (AAEH) for 14 days.

   • According to SACHDEWA A (2013)

     Excerpt Blood glucose and total lipid levels were determined in streptozotocin induced diabetic rats after oral administration of an ethanol flower extract of H rosa sinensis. The Hypoglycemic activity of this extract is comparable to that of Glibenclamide but is not mediated through insulin release.

   • According to Mamun A (2013)

     Excerpt The present study was designed to investigate the effect of ethanolic extract of Hibiscus rosa sinensis (EHBS) leaves on alloxan-induced diabetes with Dyslipidemia in rats. Treatment of alloxan-induced diabetes with most effective observed dose (2.0 mg/kg body weight) of EHBS for 1 week significantly reduced glucose level, TC, TG & LDL-C, with the increase of HDL-C & weight of kidney, pancreas & liver when compared with diabetic rats.

   • According to KAREL A (2022)

     Excerpt Hibiscus rosa-sinensis L. This study emphasizes the chemical composition, & uses of the plant for antioxidant & anti-diabetic activity as well as future prospects of harnessing its beneficial effects in the form of beverages.

   • According to SOHANI S (2021)

     Excerpt The medicinal value of the flower is described in the ancient science, Ayurveda & Chinese herbology A number of research studies proved that the different parts of Hibiscus rosa sinensis plants possesses Antioxidant, Antimicrobial, Antidiabetic, Antiulcer, Hepatoprotective, Antifertility, Antigenotoxic & Anti-inflammatory properties, which supports in treatment of countless diseases. Hibiscus rosa sinensis has been used in many herbal mix & drinks.

3. 3

   Cancer: adjuvant treatment for breast, pancreatic and prostate cancer

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rasul HO (2023)

     Excerpt The goal of this work was to screen a number of inhibitors produced from Hibiscus rosa-sinensis for possible target to inhibit the mTOR & to determine which has the greatest affinity for the receptor. By using Lipinski's rule of five to the chosen compounds, the ADMET profile & drug-likeness characteristics were further examined to assess the anti-breast cancer activity.

   • According to Khandare AD (2012)

     Excerpt To elucidate the ameliorative effect of hydroalcoholic extract of leaves of Hibiscus Rosa sinensis (HRS) in acetic acid induced experimental colitis in male Wistar rats. Ulcer area, ulcer index, spleen weight, colon weight to length ratio, macroscopic score, haematological parameters, colonic superoxide dismutase (SOD), glutathione (GSH), myeloperoxidase (MPO), Malondialdehyde (MDA), tumor necrosis factor-α (TNF-α), nitric oxide (NO) & histological changes were recorded after the treatment regimen of 11 days.

   • According to Olagbende-Dada SO (2007)

     Excerpt Cold aqueous extract of Hibiscus rosa-sinensis leaves is reported by local traditional practioners in Western Nigeria to be aphrodisiac. The gain in body & isolated sexual organs (testis, epididymis, seminal vesicle & prostate) weights were determined after treatment & compared to the value obtained from a fourth untreated group which served as the control.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.