Hyptis capitata (Kanmomiy) : medicinal properties in alcoholic extraction

Hyptis capitata (Kanmomiy, Ti-Sitwonnèl, Ti-ponpon, Chamomile, Little lemongrass, Little pompom, Camomille, petite citronnelle, Petit pompon) — family Lamiacées.

Scientific synonyms : Clinopodium capitatum (Jacq.) Sw., Hyptis decurrens (Blanco) Epling, H mariannarum Briq., H rhomboidea M.Martens & Galeotti, Mesosphaerum capitatum (Jacq.) Kuntze, Pycnanthemum decurrens Blanco, Thymus virginicus Blanco.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 34 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Fungal infection: Candida albicans

   Plant part used: Stem bark.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sumitha V (2021)

     Excerpt The present study focuses on the primary phytochemical analysis & evaluation of the antimicrobial activity of methanolic leaf extract of HC against bacterial strains such as Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli & fungal strains viz., Candida albicans, Aspergillus niger & Penicillium chrysogenum by agar well diffusion method. Moreover, the phytochemical screening revealed the presence of potential phytoconstituents which may account for the antibacterial activity of the promising medicinal herb, Hyptis capitata.

   • According to BRID H (2021)

     Excerpt The subtribe Hyptidinae contains approximately 400 Accepted species distributed in 19 genera (Hyptis, Europe, Condea, Cantinoa, Mesosphaerum, Cyanocephalus, Hypenia, Hyptidendron, Oocephalus, Medusantha, Gymneia, Marsypianthes, Leptohyphids, Martianthus, Asterohyptis, Eplingiella, Physominthe, Eriopidion & Rhaphiodon). Extracts, essential oils & isolated compounds showed a series of biological activities such as insecticide/repellent, antimicrobial & antinociceptive, justifying some of the popular uses of the plants.

   • According to To ‘Bungan N (2022)

     Excerpt Hyptis capitata is one of the important traditional medicinal plants, in which different parts of the plant are used in various countries in treating several diseases. The pharmacological study of HC showed that this plant has the potential to be developed as an antioxidant, antibacterial, antiviral & anticancer.

   • According to Kusuma IW (2014)

     Excerpt Antimicrobial activity against Propionibacterium acnes & Candida albicans was determined by an agar well diffusion method. The results showed that n-hexane, ethyl acetate & ethanol extracts of Cananga odorata, ethanolic extracts of Chromolaena odorata & Hyptis capitata & Ampelocissus cinnamomeae displayed good activity against P acnes at 25-400 microg/well of the extracts tested.

   • According to SUSANTI Y (2024)

     Excerpt Knotweed (Hyptis capitata) is a member of the genus Hyptis & the medicinal properties remain underexplored in scientific research. Phytochemical analysis showed several compounds with antibacterial potential, suggesting the need for further research of antibacterial activity against other pathogenic bacteria & exploration of additional biological activities.

2. 2

   Cancer: adjuvant treatment for hormone-dependent breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to To ‘Bungan N, (2022)

     Excerpt Ethanolic leaf extract of Hyptis capitata Jacq. As an initial screening for its anticancer potential, ethanolic leaf extract & F1 fraction were subjected to cytotoxicity test on T47D cells to obtain an IC50 value of 45.32±2.0 & >1000 µg/mL.

   • According to To ‘Bungan N (2022)

     Excerpt Hyptis capitata is one of the important traditional medicinal plants, in which different parts of the plant are used in various countries in treating several diseases. The pharmacological study of HC showed that this plant has the potential to be developed as an antioxidant, antibacterial, antiviral & anticancer.

   • According to Lee KH (1988)

     Excerpt Bioassay-directed fractionation of the cytotoxic antileukemic extracts of Prunella vulgaris, Psychotria serpens, & Hyptis capitata has led to the isolation of ursolic acid as one of the active principles. It also demonstrated marginal cytotoxicity in the KB & the human colon (HCT-8) & mammary (MCF-7) tumor cells.

   • According to To ‘Bungan N (2022)

     Excerpt Capitata have been reported to have potential anticancer properties. This study was conducted to determine the anticancer potential of the roots, stems, leaves, & flowers of H.C Organs of HC were extracted in stages using chloroform & continued with methanol to obtain eight extracts.

   • According to Sumitha V (2021)

     Excerpt The present study aims at the quantification of total phenols & flavonoids & the in vitro antioxidant potential of methanolic leaf extract of Hyptis capitata Jacq of Lamiaceae. The findings revealed that the significant amount of phenols & flavonoids might have attributed to the free radical scavenging activity of methanolic leaf extract of Capitata.

3. 3

   Osteoarthritis, arthritis, rheumatism, oedema

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Audrina M (2018)

     Excerpt One of the medical plants that can be -used as an anti-inflammation treatment is Semambu leaf (Hyptis capitata Jacq.). The test of the effectiveness of anti-inflammation was divided into your treatments which each treatment was consist of five mice which have been given negative control 0.5% CMC-Na suspension ;100 mg/KgBW, 200 mg/KgBW, 300 mg/Kg/BW of HC leaf extract.

   • According to SUMITHA V (2018)

     Excerpt The plant has some folkloric advantages such as anti-cough, antispasmodic, anti-inflammatory & wound healing properties. Hyptis capitata is a slightly aromatic folk medicinal perennial herb belongs to Lamiaceae, commonly called button-weed.

   • According to Nogodula JN (2012)

     Excerpt Hence, the Ethnopharmacologic practice of the knotweed (Hyptis capitata) was scientifically assessed for antibacterial activity, toxicity, mutagenicity & pharmacological screenings of crude leaf extract in formulation of ointment as treatment of MRSA infections.

   • According to Kashiwada Y (1998)

     Excerpt Oleanolic acid (1) was identified as an anti-HIV principle from several plants, including Rosa woodsii (leaves), Prosopis glandulosa (leaves & twigs), Phoradendron juniperinum (whole plant), Syzygium claviflorum (leaves), Hyptis capitata (whole plant), & Ternstromia gymnanthera (aerial part). capitata, was also identified as an anti-HIV agent (EC50 1.4 μg/mL, T.

   • According to Rupa D (2017)

     Excerpt Hyptis capitata Jacq. GC-MS analysis showed that HC leaves contain terpenoid compounds assumed to serve as anti-infective agents, including l-limonene, eugenol, farnesol isomers A, d-nerolidol, hexa-hydro farnesol & neo-phytadiene.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.