Jasminum sambac (Jasmen-darabi) : medicinal properties in alcoholic extraction

Jasminum sambac (Jasmen-darabi, Arabian jasmine, Jasmin d’Arabie) — family Oleacacées.

Scientific synonyms : Jasminum sambac-(L)-Soland.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 22 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 41 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rambabu B (2014)

     Excerpt The diabetic activity was studied by oral glucose tolerance test, alloxan induced diabetes, streptozotocin induced diabetes models. The present study was planned to evaluate the antidiabetic potential as well as antiulcer activity of flower extract of J.

   • According to Upaganlawar AB (2009)

     Excerpt Different extracts viz ethyl acetate (EAE) & water extract (WTE) of leaves of Jasminum sambac Linn (family: Oleaceae) were tested against alloxan induced diabetic rats. The result suggests the antidiabetic & lipid lowering activity of Jasminum sambac leaves extracts.

   • According to Yin Y (2014)

     Excerpt In this study, vasorelaxant effect of ethanol extract of jasmine flower (EEJ) on isolated rat thoracic aorta rings was investigated and [Ca 2+] was determined in vascular smooth muscle cells by laser scanning confocal microscope (LSCM). The result of aorta rings showed that EEJ could cause concentration-dependent relaxation of endothelium-intact rings precontracted with phenylephrine or KCl which was attenuated after preincubation of the rings with L-NAME and three different K+ channel inhibitors; however, indomethacin and Glibenclamide did not affect the vasodilatation of EEJ.

2. 2

   Cancer: - adjuvant treatment of liver and breast cancer

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Kalaiselvi M (2011)

     Excerpt In subchronic study, effect of multiple weekly dosing of 400 mg/kg [one-fifth of the maximum tolerated dose] of MEJS was investigated in mice for six weeks using hematological parameters, biochemical estimations of hepato-renal parameters, antioxidant status & histological observations of the tissue. In subchronic toxicity study it showed no significant alteration on any of the parameters, which was confirmed by the histological studies.

   • According to Rahman A (2011)

     Excerpt The ethanol extract of the dried leaves of Jasminum sambac was investigated for its possible analgesic & cytotoxic activities in animal models. The ethanol extract of J sambac was evaluated in vitro for antiproliferative activity against Hep-2, MCF-7 & Vero cell lines.

   • According to Kalaiselvi M (2013)

     Excerpt The anticancer activity of the ethanolic extract of Jasminum sambac [100 mg/kg bw] was investigated against Dalton's lymphoma ascites-induced lymphatic cancer in Swiss albino mice. DNA fragmentation occurred in the tumor-induced group of tissue & treatment with ethanolic extract reduced the DNA damage caused by lymphoma.

   • According to Kalaiselvi M (2012)

     Excerpt The present study was aimed to evaluate the anticancer effect of Jasminum sambac against Daltons ascites lymphoma induced Swiss albino mice in in vitro and in vivo model. The tumor cell proliferation inhibitory activity of methanolic extract showed dose dependent in both HeLa & mouse fibroblast cells.

   • According to Sengar N (2015)

     Excerpt Anti-inflammatory activity of EJS was assessed by carrageenan-induced rat paw oedema, cotton pellet-induced granuloma and Freund's adjuvant-induced arthritis models, while antipyretic activity was evaluated using Brewer's yeast induced pyrexia. EJS significantly (p<0.001) inhibited adjuvant-induced arthritis and also showed significant antipyretic activity.

3. 3

   Osteoarthritis, rheumatoid arthritis, oedema, rheumatism

   Plant part used: Flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sengar N (2015)

     Excerpt Anti-inflammatory activity of EJS was assessed by carrageenan-induced rat paw oedema, cotton pellet-induced granuloma and Freund's adjuvant-induced arthritis models, while antipyretic activity was evaluated using Brewer's yeast induced pyrexia. The study confirms the anti-inflammatory, analgesic and antipyretic activity of EJS which may be attributed to the presence of various phytoconstituents quantified especially hesperidin which have already been reported for its significant role in treatment of inflammation & associated problems.

   • According to Rambabu B (2014)

     Excerpt The ethanol extract of its flowers was investigated for its antiinflammatory & analgesic activities in animal models. The alcoholic extract at 400 mg/kg body weight reduced significantly the formation of oedema induced by carrageenan.

   • According to Hossain R (2015)

     Excerpt The objective of conducting this study is to investigate the phytochemical and pharmacological activities of both Ethanolic & Ethyl Acetate extracts of full bloomed flower of Jasminum sambac (Js) to rationalize its traditional uses as anti-inflammatory agent. Cotton pellet induced granuloma test on Wistar rat and Xylene induced ear edema test on Swiss albino mice were carried out to inspect anti-inflammatory effects of the both extracts of Js at 200 mg/kg and 400 mg/kg body weight.

   • According to Bhangale J (2012)

     Excerpt Bhangale J et al, Preliminary Study on Anti-Inflammatory & Analgesic Activities of Jasminum sambac (L) Aiton in experimental Animal Models.

   • According to Moloudi M.R (2018)

     Excerpt The traditional use of this plant has shown its analgesic, anti-depressant, anti-inflammatory, disinfectant, sedative & anti-spasmodic effects. On the other hand studies have shown the anticonvulsant & sedative effects of Jasminum sambac.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.