Lagerstroemia indica (Jèstram) : medicinal properties in alcoholic extraction

Lagerstroemia indica (Jèstram, Gestrame) — family Lythracées.

Scientific synonyms : Lagerstroemia indica-(L)-Kuntze, Murthugas indica-(L)-Kuntze.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 56 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for colorectal carcinoma

   Plant part used: flower.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to CHEN Y (2021)

     Excerpt A phytochemical investigation of the EtOH extract of the flowers of Lagerstroemia indica L. All the isolates were evaluated for their cytotoxic effects against human colon cancer cell (HCT-116), & compound 3 exhibited weak cytotoxicity with IC50 value of 28.4 μM.

   • According to YUE Z (2024)

     Excerpt (Lythraceae), known for its exquisite flowers & prolonged flowering period, is commonly employed in traditional medicinal systems across Asian countries, where it has always been consumed as tea or employed to address ailments such as diabetes, urinary disorders, coughs, fevers, inflammation, pain, & anesthesia. Extensive in vitro & in vivo experiments have examined the pharmacological activities of different extracts, revealing their potential in various domains, including but not limited to antidiabetic, anti-obesity, antitumor, antimicrobial, antioxidant, anti-inflammatory, analgesic, & hepatoprotective effects.

   • According to BEHERA A (2021)

     Excerpt This study evaluated the anticancer, antimicrobial, & hemolytic potential of zinc oxide nanoparticles (ZnO-NPs) synthesized from a novel medicinal plant Lagerstroemia indica. Thus, the synthesized ZnO-NPs from the medicinal plant LI could be used as an anticancer agent after further in vivo trials.

   • According to NISAR J (2025)

     Excerpt To assess the hepatoprotective effects of methanolic extract of Lagerstroemia indica leaves on carbon tetrachloride (CCl4)-induced liver damage in rats. Methods Fifty male Sprague Dawley rats were divided into five groups: the normal control, the CCl4 group, the CCl4 group treated with silymarin (200 mg/kg) or Lagerstroemia indica extract (200 and 400 mg/kg).

   • According to LEE KR (2015)

     Excerpt The purification of a MeOH extract from the stems of Lagerstroemia indica (Lythraceae) using repeated column chromatography afforded three new phenolic glycosides (1-3), & a new flavone derivative (4) along with fifteen known compounds (5-19). Compounds 1-19 were evaluated for their inhibitory activities on nitric oxide (NO) production in an activated murine microglial cell line & cytotoxic activities against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, & HCT-15).

2. 2

   Memory impairment, adjunctive treatment for Alzheimer’s disease

   Plant part used: leaf.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Elsawi SA (2018)

     Excerpt the present study aims to evaluate phytoconstituents of Lagerstromia indica (L.) & their effect on Alzheimer's disease (AD). The result of this investigation stated a promising effect of the 80% ethanolic extract (total extract) of LI as anti-Alzheimer's agent.

   • According to Maamoun (2018)

     Excerpt The present study aims to evaluate phytoconstituents of Lagerstroemia indica (L.) & their effect on Alzheimer's disease (AD). The result of this investigation stated a promising effect of the 80% ethanolic extract (total extract) of LI as anti-Alzheimer's agent.

   • According to AL-SNAFI AE (2019)

     Excerpt Lagerstroemia indica contained alkaloids, cardiac glycosides, tannins, saponins, sterols, triterpenes, anthraquinones, reducing compounds, flavonoids (flavanones/ dihydro-flavonols & chalcones) & phenolic glycosides (strosides A-C). LI showed anti-inflammatory, analgesic, antipyretic, antioxidant, anticancer, antimicrobial, anti-Alzheimer's, antidiabetic, hepatoprotective & antithrombin effects.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.